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Rong Zhou, PhD

faculty photo
Research Associate Professor of Radiology
Member, Institute of Translational Medicine and Therapeutics (ITMAT) , University of Pennsylvania
Member, Institute of Regenerative Medicine, University of Pennsylvania
Full Member of the Abramson Cancer Center, ACC of the University of Pennsylvania
Department: Radiology

Contact information
198 John Morgan Building
3620 Hamilton Walk
Philadelphia, PA 19104
Office: (215)-746-8747
Fax: 215-573-2113
Lab: (215)-746-8752
BS (Biomedical Engineering)
Shanghai Jiao Tong University, 1987.
PhD (Biophysics /Magnetic Resonance)
State University of New York at Buffalo, 1998.
Post-Graduate Training
Postdoctoral Fellow, University of Pennsylvania, 1998-2000.
Research Associate, University of Pennsylvania, 2000-2001.
Permanent link
> Perelman School of Medicine   > Faculty   > Details

Description of Research Expertise

Magnetic resonance imaging (MRI) and spectroscopy (MRS)
Developing imaging markers (MRI/S and PET) of metabolic signatures of cancer and heart failure.
Developing in vivo imaging markers for assessing therapeutic responses.
Stem cells and cardiac repair

Selected Publications

Zhou R, Pantel AR, Li S, Lieberman BP, Ploessl K, Choi H, Blankemeyer E, Lee H, Kung HF, Mach RH, Mankoff DA: [18F](2S,4R)4-Fluoroglutamine PET Detects Glutamine Pool Size Changes in Triple Negative Breast Cancer in Response to Glutaminase Inhibition. Cancer Research 77(6): 1476-1484, Feb 2017 2017.

Zhou R, Bansal N, Leeper DB, Glickson JD : Intracellular acidification of human melanoma xenografts by respiratory inhibitor meta-iodobenzylguanidine plus hyperglycemia: a 31P magnetic resonance spectroscopy study. Cancer Research 60: 3532-3536, 2000.

Zhou R, Mazurchuk R, and Straubinger RM: Anti-vasculature effects of doxorubicin-containing liposomes in an intracranial rat brain tumor model. Cancer Research 62: 2561-2566, 2002.

Choi H, Liu T, Nath K, Zhou R* and Chen IW*: Peptide nanoparticle with pH-sensing cargo solubility enhances cancer drug efficiency Nano Today 13: 15-22, 2017 Notes: * Co-corresponding authors.

Liu T, Choi H, Zhou R*, Chen I* (*co-corresponding authors): RES Blockade: A Strategy for Boosting Efficiency of Nanoparticle Drug. Nano Today 10: 11-21, February 2015.

Zhou R, Acton PD, Ferrari VA: Imaging Stem Cells Implanted in Infarcted Myocardium. Journal of American College of Cardiology 48(10): 2094-2106, 2006.

Qiao H, Zhang H, Zheng Y, Ponde DE, Shen D, Gao F, Bakken A, Schmitz A, Kung HF, Ferrari VA, and Zhou R: Embryonic Stem Cell Grafting in Normal and Infarcted Myocardium: Serial Assessment with MR Imaging and PET Dual Detection. Radiology 250(3): 821-829, 2009.

Zhang H, Qiao H, Frank RS, Huang B, Propert KJ, Margulies S, Ferrari VA, Epstein JA, Zhou R. : Spin-Labeling Magnetic Resonance Imaging Detects Increased Myocardial Blood Flow After Endothelial Cell Transplantation in the Infarcted Heart. Circulation: Cardiovascular Imaging. 5: 210-217, 2012.

Qiao H, Zhang H, Yamanaka S, Patel VV, Petrenko NB, Huang B, Muenz LR, Ferrari VA, Boheler KR and Zhou R: Long-term Improvement in Post-Infarct Left Ventricular Global and Regional Contractile Function Mediated by Embryonic Stem Cell-Derived Cardiomyocytes. Circulation: Cardiovascular Imaging 4(1): 33-41, 2011.

Li LZ*, Zhou R*, Xu HN, Moon L, Zhong T, Kim EJ, Qiao H, Reddy R, Leeper D, Chance B, Glickson JD.: Quantitative magnetic resonance and optical imaging biomarkers of melanoma metastatic potential. Proc Natl Acad Sci USA 106(16): 6608-13, 2009 Notes: *equal contributing 1st authors.

Zhou R, Idiyatullin D, Moeller S, Corum C, Zhang H, Qiao H, Zhong J, Garwood M : SWIFT Detection of SPIO Labeled Stem Cells Grafted in the Myocardium. Magnetic Resonance in Medicine 63: 1154-1161, 2010.

Zhou R, Thomas DT, Qiao H, Bal H, Choi SR, Alavi A, Ferrari VA, Kung HF and Acton PD.: In vivo Detection of Stem Cells Grafted in the Infarcted Rat Myocardium. Journal of Nuclear Medicine 46: 816-822, 2005.

Zhou R, Pickup S, Yankeelov T, Springer Jr. CS, Glickson JD : Simultaneous measurement of AIF and tumor pharmacokinetics in mice by dynamic contrast enhanced imaging: effects of transcytolemmal water exchange. Magnetic Resonance in Medicine 52: 248-257, 2004.

Zhou R, Steve Pickup, Jerry Glickson, Craig Scott and Victor Ferrari : Assessment of Global and Regional Myocardial Function in the Mouse Using Cine and Tagged MRI. Magnetic Resonance in Medicine 49: 760-764, 2003.

Kostetskii I, Li J, Xiong Y, Zhou R, Ferrari VA, Patel VV, Molkentin JD, Radice GL: Induced deletion of the N-Cadherin gene in the heart leads to dissolution of the intercalated disc structure. Circulation Research 96: 346-354, 2005.

Kook H, Lepore JJ, Gitler AD, Lu MM, Wing-Man Yung W, Mackay J, Zhou R, Ferrari V, Gruber P, and Epstein JA: Cardiac hypertrophy and histone deacetylase-dependent transcriptional repression mediated by the atypical homeodomain protein Hop. J Clin Invest 112: 863-871, 2003.

Abtahian F, Guerriero A, Lu M, Zhou R, Mocsai A, Myers E, Huang B, Jackson D, Ferrari VA, Tybulewicz V, Lowell CA, Lepore JJ, Koretzky GA, and Kahn M: Separation of blood and lymphatic vascular networks is regulated by the hematopoietic signaling proteins SLP-76 and SYK. Science 299: 247-251, 2003.

Auricchio A, Zhou R, Wilson J, Glickson J: In vivo detection of gene expression in liver by 31P nuclear magnetic resonance spectroscopy employing creatine kinase as a marker gene. Proceeding of National Academy of Science (USA) 98: 5205-5210, 2001.

Lowell AN, Qiao H, Liu T, Ishikawa T, Zhang H, Oriana S, Wang M, Ricciotti E, FitzGerald GA, Yamakoshi Y and Zhou R: Functionalized Low-Density Lipoprotein Nanoparticles for in Vivo Enhancement of Atherosclerosis on Magnetic Resonance Images. Bioconjugate Chemistry 23: 2313-2319, 2012.

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Last updated: 12/20/2017
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