PET Brain Imaging of Dementia and Epilepsy
SPECT Brain Imaging of Parkinson's Disease
PET/CT Oncologic Imaging
PET Myocardial Imaging
Radionuclide Therapy
General Nuclear Medicine
Dr. Dubroff is clinician scientist who uses Positron Emission Tomography (PET) and Single Photon Emission Computed Tomography to better understand the molecular mechanisms of drug abuse, including nicotine dependence and opioid use disorder, as well as neurodegenerative disease, including Parkinson's and Alzheimer's diseases. He collaborates with investigators in the Departments of Psychiatry and Neurology. His studies are supported by the National Institute of Drug Abuse (NIDA), the National Heart, Lung, and Blood Institute (NHLBI), the Michael J. Fox Foundation, and industry.
Neuroreceptor PET Imaging
Molecular Imaging of Neurological and Psychiatric Disease
Addiction
Cardiac PET Imaging
Brain Plasticity
Selected Publications
Wetheril RR, Doot RK, Young AJ, Lee H, Schubert EK, Wiers CE, Leone FT, Mach RH, Kranzler HR, Dubroff JG: Using 18F-NOS PET Imaging to Measure Pulmonary Inflammation in Electronic and Combustible Cigarette Users: A Pilot Study. J Nucl Med jan 2023 Notes: doi: 10.2967/jnumed.122.264529. Online ahead of print.
Rojulpote C, Bhattaru A, Jean C, Patel V, Vidula M, Selvaraj S, Chandra A, Dubroff J, Peyster E, Clancy C, Patterson K, Marchlinski F, Rossman M, Goldberg L, and Bravo P
: Effect of Timing, Immunotherapy, and Biopsy-Status in Monitoring Therapy Response in Suspected Cardiac Sarcoidosis. JACC: Cardiovascular Imaging 15(11): 1944-1955, October 2022.
Love T, Shabalin A, Kember R, Docherty A, Zhou H, Koppelmans V, Gelernter J, Baker A, Hartwell E, Dubroff J, Zubieta JK, and Kranzler HR: Unique and Joint Associations of Polygenic Risk for Major Depression and Opioid Use Disorder with Endogenous Opioid System Function. Neuropsychopharmacology 47(10): 1784-90, Sep 2022 Notes: doi: 10.1038/s41386-022-01325-1.
Schroeder JA, Cao Q, Sotirchos VS,Gillman JA, Anderson T, Pilati S, Dubroff JG, Farwell M, Kozlov A, Korhonen K, Pryma DA, Pantel AR: Perfusion-only Imaging in Pregnant Women: A Comparative Reader Study with Implications for Practice Patterns. Medicine 101(39), Sep 2022.
Doot RK, Young AJ, Nasrallah IN, Wetherill RR, Siderowf A, Mach RH, Dubroff JG: [18F]NOS PET brain imaging suggests elevated neuroinflammation in
idiopathic Parkinson’s disease. Cells 11(19): 3081, Sep 2022.
Zuroff L, Wisseb LEM, Glenn T, Xie S, Nasrallah I, Habes M, Dubroff J, de Flores R, Xie L, Yushkevich P, Doshi J, Davatsikos C, Wolka DA, Dasa S, Mechanic-Hamilton D: Self- and partner-reported subjective memory complaints: association with objective cognitive impairment and risk of decline. JAD reports 6(1): 411-430, Jul 2022.
Phillips JS, Nitchie FJ, Da Re F, Olm CA, Cook PA, McMillan CT, Gee JC, Dubroff JG, Grossman M, Nasrallah IM: Rates of longitudinal change in 18F-flortaucipir PET vary by brain region, cognitive impairment, and age in atypical Alzheimer's disease. Alzheimer's & Dementia 18(6): 1235-47, Jun 2022 Notes: doi: 10.1002/alz.12456. Epub 2021 Sep 13.
Aamodt WW, Dubroff JG, Cheng G, Taylor B, Wood S, Duda JE, and Morley JF
: Gait abnormalities and non-motor symptoms predict abnormal dopaminergic imaging in presumed drug-induced parkinsonism
npj Parkinson's Disease 8(1): 53, Apr 2022.
Patterson KC, Rosenbach M, Bravo PE, Dubroff JG: Stable Extent of Recurrently Active Cardiac and Cutaneous Sarcoidosis. Front Med (Lausanne)
8(729229), Dec 2021 Notes: doi: 10.3389/fmed.2021.729229.
Selvaraj S, Khan MS, Wiener PC, de Feria A, Rojulpote C, Julien H,
Jacoby D, Litt H, Pryma D, Dubroff J, Guerraty MA, Bravo P: Incremental Prognostic Value of Visually Estimated Coronary Artery Calcium in Patients Undergoing Positron Emission Tomography Imaging. Open Heart 8(1), May 2021 Notes: doi: 10.1136/openhrt-2021-001648.
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Last updated: 03/21/2023
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