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Gregory J. Nadolski, M.D.

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Assistant Professor of Radiology at the Hospital of the University of Pennsylvania
Co-Director, Penn Image Guided Interventions (PIGI) Laboratory
Active Radiologist, Penn Presbyterian Medical Center
Active Radiologist, Pennsylvania Hospital
Attending Radiologist, Hospital of the University of Pennsylvania
Attending Radiologist, Philadelphia Veteran's Affairs Medical Center
Director Research Oversight, Interventional Radiology University of Pennsylvania
Center for Lymphatic Imaging and Interventions, University of Pennsylvania
Chair IR/DR Residency Selection Committee, University of Pennsylvania
Department: Radiology

Contact information
Hospital of the University of Pennsylvania
Department of Radiology
1 Silverstein
3400 Spruce Street
Philadelphia, PA 19104
Office: 215.662.7892
Fax: 215.615.3545
Education:
B.S. (Biochemistry)
University of Wisconsin, Madison, WI , 2001.
M.D. (Medicine)
Indiana University School of Medicine, Indianapolis, IN , 2007.
MS (Translational Research)
University of Pennsylvania, 2017.
Post-Graduate Training
Intern, Surgery, DIRECT Pathway, Department of Radiology, Hospital of the University of Pennsylvania, Philadelphia, PA , 2007-2009.
Resident, Diagnostic Radiology, DIRECT Pathway, Department of Radiology, Hospital of the University of Pennsylvania, Philadelphia, PA , 2009-2011.
Fellow, Interventional Radiology, DIRECT Pathway, Department of Radiology, Hospital of the University of Pennsylvania, Philadelphia, PA , 2011-2012.
Resident, Diagnostic Radiology, DIRECT Pathway, Department of Radiology, Hospital of the University of Pennsylvania, Philadelphia, PA , 2012-2013.
Certifications
ACLS certified , 2007.
American Board of Radiology , 2013.
Certificate in Interventional Radiology/Diagnostic Radiology, 2017.
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Description of Clinical Expertise

My research and clinical interests include multimodality therapies for the treatment of hepatocellular carcinoma and liver dominant metastatic cancer.

I have initiated two clinical trials at the Hospital of the University of Pennsylvania for treating hepatocellular carcinoma. One involves combining transcatheter embolization with external beam radiation, and the other combines transcatheter embolization with an investigational oral chemotherapeutics.

Clinical Trials:
1. A Pilot Trial of Transarterial Chemoembolization With or Without Stereotactic Body Radiation Therapy for Hepatocellular Carcinoma Patients Awaiting Liver Transplantation, Hospital of the University of Pennsylvania (UPCC16213)

2. Phase I-II Clinical Trial of the Safety of Hydroxychloroquine Combined with Transarterial Chemoembolization for Unresectable Hepatocellular Carcinoma, Hospital of the University of Pennsylvania (UPCC22213)

My other area of clinical and research interest is lymphatic injury, dysfunction, and malformations. Clinically, I perform thoracic duct embolization to treat chylothorax. I participate in research investigating novel lymphatic interventions to treat chylothorax, chylous ascites, refractory ascites and protein losing enteropathy.

Description of Research Expertise

In addition to my research investigating lymphatic interventions and multimodality cancer therapies, I also conduct research on vascular remodeling as it relates to hemodialysis access malfunction and peripheral arterial disease.

In this research, I am investigating a minimally invasive near infrared imaging system to evaluate hemodialysis access. The goal of this research is to detect changes in blood vessels that lead to stenosis before it becomes symptomatic. Detection of such changes at any early stage could improve development and monitor response of therapies to treat vascular disease.

Selected Publications

Pieper CC, Hur S, Sommer CM, Nadolski G, Maleux G, Kim J, Itkin M.: Back to the Future: Lipiodol in Lymphography-From Diagnostics to Theranostics. Invest Radiol 54(9): 600-615, September 2019.

Alexander ES, Nadolski GJ, Soulen MC, Stavropoulos SW, Hunt SJ, Gade TP, Itkin M, Shamimi-Noori S.: Iatrogenic celiac and hepatic artery dissections during intra-arterial regional tumor therapies: a 16-year retrospective review. Abdominal Radiology Aug 2019 Notes: epub ahead of print.

Currie BM, Hoteit MA, Ben-Josef E, Nadolski GJ, Soulen MC.: Radioembolization-Induced Chronic Hepatotoxicity: A Single-Center Cohort Analysis. JVIR. epub ahead of print (eds.). July 2019 Notes: epub ahead of print.

Chick JFB, Nadolski GJ, Lanfranco AR, Haas A, Itkin M.: Dynamic Contrast-Enhanced Magnetic Resonance Lymphangiography and Percutaneous Lymphatic Embolization for the Diagnosis and Treatment of Recurrent Chyloptysis. J Vasc Interv Radiol 30(7): 1135-1139, July 2019.

Benjamin JL, Rychik J, Johnstone JA, Nadolski GJ, Itkin M.: Cost-Effectiveness of Percutaneous Lymphatic Embolization for Management of Plastic Bronchitis. World J Pediatr Congenit Heart Surg 10(4): 407-413, July 2019.

Tischfield DJ, Ackerman D, Noji M, Chen JX, Johnson O, Perkons NR, Nadolski GJ, Hunt SJ, Soulen MC, Furth EE, Gade TP.: Establishment of hepatocellular carcinoma patient-derived xenografts from image-guided percutaneous biopsies. Scientific Reports 9(1), July 2019.

Shi D, Kiefer RM, Nishiofuku H, Cortes A, Nadolski GJ, Hunt SJ, Avritscher R, Gade TPF.: Angiographic Atlas of the Visceral Vascular Anatomy in Translational Rat Models. JVIR June 2019 Notes: epub ahead of print.

Habibollahi P, Shamchi SP, Dʼsouza J, Weber CN, Langer JE, Nadolski GJ, Chauhan A.: Predictive Value of Abnormal Findings on Covered Transjugular Intrahepatic Portosystemic Shunt Baseline Doppler Sonography. Ultrasound Quarterly May 2019 Notes: epub ahead of print.

Patel V, McLaughlin SW, Shlansky-Goldberg R, Gade T, Bonshock R, Hunt S, Stavropoulos SW, Trerotola SO, Soulen MC, Nadolski G.: Complication rates of percutaneous biliary drainage in the presence of ascites. Abdominal Radiology 44(5): 1901-1906, May 2019.

B. Park, M. Silk, D. Kwon, G. Nadolski, S. Hunt, T. Gade: Registration of 3D holographic models of patient imaging onto a CT grid: assessment of manual and automatic techniques using HoloLens. Journal of Vascular and Interventional Radiology 30(3): S129, March 2019.

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Last updated: 09/03/2019
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