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Mehran Makvandi, PharmD, RPh, ANP

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Instructor A of Radiology
Instructor, University of Pennsylvania, Perelman School of Medicine, Department of Radiology, Philadelphia, PA
Department: Radiology

Contact information
Perelman School of Medicine
University of Pennsylvania
Department of Radiology
Nuclear Medicine and Clinical Molecular Imaging
231 S. 34th Street
Philadelphia, PA 19104
Office: 215-746-8755
Education:
N/A (Chemistry)
University of New Mexico, 2009.
PharmD. (Pharmacology)
University of New Mexico, 2013.
Post-Graduate Training
Training Internship - Nanoscience and Microsystems, University of New Mexico Sandia National Laboratories; Advanced Materials Lab, Albuquerque, NM, 2009-2009.
Postdoctoral Research Fellowship, University of Pennsylvania, Perelman School of Medicine, Philadelphia, PA, 2013-2016.
Certifications
Aseptic Technique , 2010.
Radiation Safety: Positron-emitting Isotopes , 2013.
Basic Life Support (BLS) certification , 2016.
ABSL-2 Working Safely with Laboratory Animals , 2016.
CITI, 2016.
Blood Borne Pathogens, 2016.
HITECH, 2016.
DOT Training for Highway Shippers and Transporters of Radiopharmaceuticals , 2016.
HIPAA , 2016.
Radiation Safety: Traditional, 2016.
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Selected Publications

Batra V, Makvandi M, Zuppa AF, Patel N, Elias J, Pryma DA, Maris JM.: Dexmedetomidine does not interfere with meta-iodobenzylguanidine (MIBG) uptake at clinically relevant concentrations. Pediatr Blood Cancer 64(4): e26268, April 2017.

Chan HS, Konijnenberg MW, Daniels T, Nysus M, Makvandi M, de Blois E, Breeman WA, Atcher RW, de Jong M, Norenberg JP. : Improved safety and efficacy of 213Bi-DOTATATE-targeted alpha therapy of somatostatin receptor-expressing neuroendocrine tumors in mice pre-treated with L-lysine. EJNMMI Res 6(1): 83, Dec 2016.

Lee I, Lieberman BP, Li S, Hou C, Makvandi M, Mach RH. : Comparative evaluation of 4 and 6-carbon spacer conformationally flexible tetrahydroisoquinolinyl benzamide analogues for imaging the sigma-2 receptor status of solid tumors. Nucl Med Biol 43(11): 721-731, Aug 2016.

Makvandi M, Xu K, Lieberman BP, Anderson RC, Sander Effron S, Winters H, Zeng C, McDonald ES, Pryma DA, Greenberg RA, and Mach RH. : A radiotracer strategy to quantify PARP-1 expression in vivo provides a biomarker that can enable patient selection for PARP inhibitor therapy. Cancer Research 76(15): 4516-24, Aug 2016.

Anderson RC, Makvandi M, Xu K, Lieberman BP, Zeng C, Pryma DA, Mach RH.: Iodinated benzimidazole PARP radiotracer for evaluating PARP1/2 expression in vitro and in vivo. Nucl Med Biol 43(12): 752-758, Aug 2016.

Edmonds CE, Makvandi M, Lieberman BP, Xu K, Zeng C, Li S, Hou C, Lee H, Greenberg RA, Mankoff DA, and Mach RH. : [18F]FluorThanatrace uptake as a marker of PARP1 expression and activity in breast cancer. Am J Nucl Med Mol Imaging 6(1): 94-101, Jan 2016.

Makvandi M, Lieberman BP, LeGeyt B, Hou C, Mankoff DA, Mach RH and Pryma DA. : The pre-clinical characterization of an alpha-emitting sigma-2 receptor targeted radiotherapeutic. Nuclear Medicine and Biology 43(1): 25-41, Jan 2016.

Mehran Makvandi: Poly(ADP-ribose) Polymerase 1 as a novel target for alpha-particle therapy in High-Risk Neuroblastoma. AACR - DNA damage and Repair, Montreal Canada 2016 Notes: Poster Presentation.

Mehran Makvandi: A radiotracer strategy to quantify PARP-1 expression as a predictive biomarker for PARP inhibitor therapy 4th annual scientific symposium, Basser Center for BRCA 2016 Notes: Poster Presentation.

Makvandi M, Anderson RC, Hou C, Xu K, Greenberg RA, Maris JM, Mach RH and Pryma DA. : Poly(ADP-ribose) Polymerase-1 as a novel target for alpha particle therapy. 42nd annual Pendergrass Symposium. Philadelphia, PA 2016 Notes: Poster Presentation.

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Last updated: 11/15/2017
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