Perelman School of Medicine at the University of Pennsylvania

Center for Research on Reproduction and Women's Health

Samantha F Butts

faculty photo
Associate Professor of Obstetrics and Gynecology at the Hospital of the University of Pennsylvania
Attending Physician, Department of Obstetrics and Gynecology, Division of REI, Hospital of the University of Pennsylvania, Philadelphia, PA
Attending Physician, Reproductive Surgical Facility, Hospital of the University of Pennsylvania, Philadelphia, PA
Member, Center for Research on Reproduction and Women's Health
Associate Scholar, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania
Member, Center for Excellence in Environmental Toxicology, Endocrine Disruptors Core
Member, Council of the Penn Forum for Women Faculty
Member, University of Pennsylvania Academic Planning and Budget Committee
Department: Obstetrics and Gynecology

Contact information
Penn Fertility Care
Center for Reproductive Medicine and Surgery
University of Pennsylvania Medical Center
3701 Market Street, 8th Floor
Philadelphia, PA 19104
Office: 215-662-2975
Fax: 215-349-5512
BA (History and Science-cum laude)
Harvard University, Cambridge MA, 1994.
Harvard University School of Medicine, Boston, MA, 1998.
University of Pennsylvania School of Medicine, Philadelphia, PA, 2006.
Post-Graduate Training
Resident in Obstetrics and Gynecology, The Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, 1998-2002.
Fellow in Reproductive Endocrinology and Infertility, The Hospital of the University of Pennsylvania, Philadelphia, PA, 2002-2005.
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Description of Research Expertise

Environmental Reproductive Toxicology; Reproductive Health Disparities; Reproductive Senescence; In Utero Programming of Ovarian Function and Somatic Growth

Description of Clinical Expertise

Reproductive Surgery, In Vitro Fertilization, Early Menopause, Diminished Ovarian Reserve, Ovulation Induction

Selected Publications

Butts SF, Seifer DB, Koelper N, Senapati S, Sammel MD, Hoofnagle AN, Kelly A, Krawetz SA, Santoro N, Zhang H, Diamond M, Legro RS: Vitamin D deficiency is associated with poor ovarian stimulation outcome in PCOS but not unexplained infertility. Journal of Clinical Endocrinology and Metabolism 104: 369-378, 2019.

Shaffer RM, Ferguson KK, Sheppard L, James-Todd J, Butts S, Chandrasekaran S, Swan SH, Barrett ES, Nguyen R, Bush N, McElrath TF, Sathyanarayana S: Maternal urinary phthalate metabolites in relation to gestational diabetes and glucose intolerance during pregnancy. Environment International 123: 588-596, 2019.

Chan JL, Senapati S, Johnson LNC, DiGiovanni L, Voong C, Butts SF, Domchek SM.: Risk factors for sexual dysfunction in BRCA mutation carriers following risk-reducing salpingo-oophorectomy. Menopause 2018 Notes: epub ahead of print July 16, 2018.

Price JT, Zimmerman LD, Lee S, Butts SF.: Race and route of hysterectomy: investigating disparities in minimally invasive gynecological surgery. American Journal of Obstetrics and Gynecology 217: e1-10, November 2017 Notes: Selected by the journal Obstetrics and Gynecology as one of the top articles on disparities published in 2018:

Sathyanarayana S, Butts S, Wang C, Barrett E, Nguyen R, Schwartz SM, Haaland W, Swan S.: Early pregnancy phthalate exposure in relation to sex steroid hormone concentrations and birth outcomes Journal of Clinical Endocrinology and Metabolism(102), March 2017 Notes: Selected for the Endocrine Society Thematic Issue on Pediatric Endocrinology, July, 2018.

Garin M, Butts SF, Sarwer DB, Allison KC, Dokras A: Ghrelin is Independently Associated with Anti-Mullerian Hormone Levels in Overweight and Obese but not Lean Women with Polycystic Ovary Syndrome. Clinical Endocrinology 55(3): 907-913, March 2017.

Feldman RA, O'Neill K, Butts SF, Dokras A: Antimullerian hormone levels and cardiometabolic risk in young women with polycystic ovary syndrome. Fertil Steril 107(1): 276-281, January 2017.

Suneeta Senapati MD MSCE, Mary D Sammel ScD, Samantha F. Butts MD MSCE, Peter Takacs, MD PhD, Karine Chung MD MSCE, Kurt T Barnhart MD MSCE: Predicting First Trimester Pregnancy Outcome: Derivation of a Multiple Marker Test. Fertility and Sterility 106: 1725-1732, 2016.

Hansen K, He ALW, Styer AK, Wild RA, Butts S, Engmann L, Diamond MP, Legro RS, Coutifaris C, Alvero R, Robinson RD, Casson P, Christman GM, Huang H, Santoro N, Eisenberg E, Zhang H.: Predictors of Pregnancy and Live-Birth in Couples with Unexplained Infertility following Ovarian Stimulation-Intrauterine Insemination Fertil Steril 105(6): 1575-1583. 2016.

McLaren JF, Barnhart KT, Sammel MD, Appleby DH, Butts SF: Success of the two-dose methotrexate protocol for treatment of ectopic pregnancy in women with a history of prior ectopic pregnancy. J Reprod Med 59(4): 379-384, August 2014.

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Last updated: 03/22/2019
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