Jinbo Chen, Ph.D.
Professor of Biostatistics in Biostatistics and Epidemiology
Senior Scholar, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania Perelman School of Medicine
Senior Scholar, Institute of Biomedical Informatics, University of Pennsylvania Perelman School of Medicine
Associate Director, Penn Center for Precision Medicine
Associate Director, Penn Medicine Biobank
Director, Statistical Center for Translational Research in Medicine (SC-TRM)
Lead Biostatistician, Penn Medicine Biobank (PMBB)
Member, Senior Scientific Advisory Committee, Penn Center for AI and Data Science for Integrated Diagnostics
Member, Executive Faculty Committee, Penn Medicine AI2D center
Department: Biostatistics and Epidemiology
Graduate Group Affiliations
Contact information
University of Pennsylvania Perelman School of Medicine,
Department of Biostatistics, Epidemiology and Informatics
203 Blockley Hall
423 Guardian Drive
Philadelphia, PA 19104
Department of Biostatistics, Epidemiology and Informatics
203 Blockley Hall
423 Guardian Drive
Philadelphia, PA 19104
Office: 215-746-3915
Fax: 215-573-1050
Fax: 215-573-1050
Email:
jinboche@upenn.edu
jinboche@upenn.edu
Publications
Links
Search PubMed for articles
CCEB > Statistical Genetics and Genomics
Center for Clinical Epidemiology and Biostatistics Faculty
Search PubMed for articles
CCEB > Statistical Genetics and Genomics
Center for Clinical Epidemiology and Biostatistics Faculty
Education:
B.S. (Physics)
Beijing Normal University, P.R. China, 1992.
M.S. (Biostatistics)
University of Washington, Seattle, WA, 1999.
Ph.D. (Biostatistics)
University of Washington, Seattle, WA, 2002.
Permanent linkB.S. (Physics)
Beijing Normal University, P.R. China, 1992.
M.S. (Biostatistics)
University of Washington, Seattle, WA, 1999.
Ph.D. (Biostatistics)
University of Washington, Seattle, WA, 2002.
Description of Research Expertise
Dr. Jinbo Chen’s primary areas of research include the development of statistical methods for designing and analyzing two-phase epidemiologic studies, methodological and collaborative work in genetic association studies of complex diseases, and the development and evaluation of risk prediction models. Dr. Chen has published numerous methods papers on haplotype analysis using data from cohort, nested case-control, and matched case-control designs, methods on exploring gene-gene and gene-environment interactions, and efficient methods for screening SNPgenotypes. Her recent work has focused on design and analyses issues arising from studies of complex genetic and environmental effects on pregnancy-related and early-life disorders. Dr. Chen has been collaborating with researchers on dissecting genetic and environmental influences on the risk of biliary tract cancer, childhood leukemia, preterm birth, food allergy, and cardio-metabolic and cardiovascular diseases.
Selected Publications
Chen J, Chatterjee N: Haplotype-based association analysis in cohort and nested case-control studies. Biometrics 62(1): 28-35, 2006.Chen J, Pee D, Ayyagari R, Graubard B, Schairer C, Byrne C, Benichou J, Gail, MH: Projecting absolute invasive breast cancer risk in white women with a model that includes mammographic density. Journal of the National Cancer Institute 98(17): 1215-1226, 2006.
Chen J, Peters U, Foster C, Chatterjee N: A haplotype-based test of association using data from cohort and nested case-control epidemiological studies. Human Heredity 58(1): 18-29, 2004.
Chen J, Breslow NE: Semiparametric efficient estimation for the auxiliary outcome problem with the conditional mean model. Canadian Journal of Statistics 32(4): 359-372, 2004.
Sakado LC, Gao YT, Chen BE, Chen J, Rosenberg P, Rashid A, Deng J, Shen MC, Wang BS, Han TQ, Zhang BH, Cohen-Webb H, Yeager M, Welsh R, Chanock S, Fraumeni JF, Hsing AW: Prostaglandin-endoperoxide synthase 2(PTGS2) gene polymorphisms and risk of biliary tract cancer and gallstones: A population-based study in Shanghai, China. Carcinogenesis 27(6): 1251-1256, 2006.
Engels EA, Chen J, Viscidi RP, Shah KV, Daniel RW, Chatterjee N, Klebanoff MA : Poliovirus vaccination during pregnancy, maternal seroconversion to Simian virus 40, and risk of childhood cancer. American Journal of Epidemiology 160(4): 306-316, 2004.
Baccarelli A, Hou L, Chen J, Lissowska J, El-Omar EM, Grillo P, Giacomini SM, Yaeger M, Bernig T, Zatonski W, Fraumeni JF Jr, Chanock SJ, Chow WH: Mannose-binding lectin-2 genetic variation and stomach cancer risk. International Journal of Cancer 119(8): 1970-1975, 2006.
Engels EA, Brock MV, Chen J, Gillison M, Hooker C, Moore RD: Elevated incidence of lung cancer among HIV-infected individuals. Journal of Clinical Oncology 24(9): 1383-1388, 2006.
Fossa SD, Chen J, Schonfeld S, McGlynn K, McMaster M, Gail MH, Travis LB: Risk of contralateral testicular cancer: a population-based study of 29,515 U.S. men. Journal of the National Cancer Institute 97(14): 1056-1066, 2005.
Engels EA, Chen J, Hartge P, Cerhan JR, Davis S, Severson RK, Cozen W, Viscidi RP: Antibody responses to simian virus 40 T antigen: a case-control study of non-Hodgkin’s lymphoma. Cancer Epidemiology, Biomarkers & Prevention 14(2): 521-524, 2005.