Rexford S. Ahima

faculty photo
Professor of Medicine
Director , Penn Diabetes and Endocrinology Research Center Mouse Phenotyping, Physiology and Metabolism Core
Faculty, Institute of Neurological Sciences, University of Pennsylvania
Staff Endocrinologist, Hospital of the University of Pennsylvania
Staff Endocrinologist, Presbyterian Medical Center, Philadelphia, PA
Director, Weight Management and Metabolism Clinic, Presbyterian Medical Center, Philadelphia
Faculty Member, Neuroscience Graduate Group, University of Pennsylvania School of Medicine
Associate Director, Institute for Diabetes, Obesity and Metabolism, University of Pennsylvania
Director, Obesity Unit, Institute for Diabetes, Obesity and metabolism, University of Penn
Member of Diabetes Research Center Executive Committee, Perelman School of Medicine at the University of Pennsylvania
Department: Medicine

Contact information
Department of Medicine
Division of Endocrinology, Diabetes & Metabolism
12-104 Smilow Translational Research Center
3400 Civic Center Boulevard, Building 421
Philadelphia, PA 19104-6149
Office: (215) 573-1872
Fax: 215-746-8931
Lab: (215) 573-1874
B.Sc. (Endocrinology)
University of London, 1981.
University of Ghana Medical School, 1986.
Ph.D (Neuroscience)
Tulane University, New Orleans, LA, 1992.
Permanent link

Description of Research Expertise

Research Interests:
Metabolic effects of circadian disruption
Role of lipid droplet proteins in lipid and glucose metabolism
Role of myokines in glucose and lipid metabolism
Brain insulin signaling and dementia

Key words: Brain, liver, adipose, adipokine, neuroendocrine, insulin, neuropeptide, obesity, diabetes.

Description of Research:
My laboratory is interested in central and peripheral regulation of energy homeostasis, and glucose and lipid metabolism. Adipokines, myokines, cytokines and other factors affect feeding, energy expenditure and glucose and lipid metabolism, through endocrine and paracrine signaling the brain and peripheral organs. Understanding these complex pathways may lead to better diagnostic and therapeutic tools for obesity, diabetes and other metabolic diseases.

1. Connecting leptin sensitivity and metabolism in feeding entrainment
2. Genetic determinants of leanness
3. Brain insulin signaling and dementia
4. Role of IPMK in glucose and lipid metabolism

Laboratory personnel:
Fred Anokye-Danso, PhD; Laboratory Manager; Technical Director of Penn Diabetes Research Center MPPM Core
Xiaoyan Yi, MD; Research Specialist, Penn Diabetes Research Center MPPM Core
Charles Addo-Yobo, BA; Technician, Penn Diabetes Research Center MPPM Core
Laura Scolaro, PhD; Postdoctoral fellow
Kyewon Park, PhD; Postdoctoral fellow
Phoebe Dacha, MD; Postdoctoral fellow
Erin Beacham; Penn School of Engineering
Doreen Agboh, BA; Research Scientist
Rotonya Carr, MD; Assistant Professor of Medicine

Description of Other Expertise

Metabolic phenotyping of mouse models of obesity, diabetes and dyslipidemia



Description of Itmat Expertise

Neuroendocrinology of obesity
Brain metabolism
back to top
Last updated: 03/25/2016
The Trustees of the University of Pennsylvania