Susan W Volk

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Associate Professor, Small Animal Surgery, University of Pennsylvania School of Veterinary Medicine

Contact information
Section of Surgery
Department of Clinical Studies - Philadelphia
University of Pennsylvania School of Veterinary Medicine
312 Hill Pavilion
380 S. University Ave
Philadelphia, PA 19104-4539
Office: 215-898-0635
Fax: 215-573-6050
University of Pennsylvania College of Arts and Sciences, 1991.
University of Pennsylvania, 1995.
University of Pennsylvania, 1998.
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Description of Research Expertise

The goals of the Volk laboratory are to understand regulatory mechanisms governing dynamic interactions between cells and their surrounding extracellular matrix in the wound healing-fibrosis-cancer progression triad and to apply this knowledge to develop innovative regenerative and oncologic therapies for veterinary and human patients.

Description of Itmat Expertise

The research interests of my laboratory focus on defining regulatory cues important to direct progenitor cell homing to sites of injury, as well as, in vitro and in vivo signals important to direct their differentiation into appropriate target cell types for use in tissue engineering strategies in human and veterinary medicine. Current work focuses on defining cellular and molecular mechanisms by which mesenchymal progenitor cells improve cutaneous wound repair and elucidating the role of the extracellular matrix in modulation of reparative and progenitor cell activities during tissue repair and regeneration.

Selected Publications

Rak Gregory D, Osborne Lisa C, Siracusa Mark C, Kim Brian S, Wang Kelvin, Bayat Ardeshir, Artis David, Volk Susan W: IL-33-Dependent Group 2 Innate Lymphoid Cells Promote Cutaneous Wound Healing. The Journal of investigative dermatology 136(2): 487-96, Feb 2016.

Han Ziying, Bart Stephen M, Ruthel Gordon, Vande Burgt Nathan H, Haines Kathleen M, Volk Susan W, Vite Charles H, Freedman Bruce D, Bates Paul, Harty Ronald N: Ebola virus mediated infectivity is restricted in canine and feline cells. Veterinary microbiology 182: 102-7, Jan 2016.

Shen Yu-I, Song Hyun-Ho G, Papa Arianne E, Burke Jacqueline A, Volk Susan W, Gerecht Sharon: Acellular Hydrogels for Regenerative Burn Wound Healing: Translation from a Porcine Model. The Journal of investigative dermatology 135(10): 2519-29, Oct 2015.

Glennie Nelson D, Yeramilli Venkata A, Beiting Daniel P, Volk Susan W, Weaver Casey T, Scott Phillip: Skin-resident memory CD4+ T cells enhance protection against Leishmania major infection. The Journal of experimental medicine 212(9): 1405-14, Aug 2015.

Brisson Becky K, Mauldin Elizabeth A, Lei Weiwei, Vogel Laurie K, Power Ashley M, Lo Albert, Dopkin Derek, Khanna Chand, Wells Rebecca G, Puré Ellen, Volk Susan W: Type III Collagen Directs Stromal Organization and Limits Metastasis in a Murine Model of Breast Cancer. The American journal of pathology 185(5): 1471-86, May 2015.

Miedel Emily L, Brisson Becky K, Hamilton Todd, Gleason Hadley, Swain Gary P, Lopas Luke, Dopkin Derek, Perosky Joseph E, Kozloff Kenneth M, Hankenson Kurt D, Volk Susan W: Type III collagen modulates fracture callus bone formation and early remodeling. Journal of orthopaedic research : official publication of the Orthopaedic Research Society 33(5): 675-84, May 2015.

Sebastian Anil, Iqbal Syed A, Colthurst James, Volk Susan W, Bayat Ardeshir: Electrical stimulation enhances epidermal proliferation in human cutaneous wounds by modulating p53-SIVA1 interaction. The Journal of investigative dermatology 135(4): 1166-74, Apr 2015.

Wormser C, Mariano A, Holmes E S, Aronson L R, Volk S W: Post-transplant malignant neoplasia associated with cyclosporine-based immunotherapy: prevalence, risk factors and survival in feline renal transplant recipients. Veterinary and comparative oncology Oct 2014.

Ud-Din Sara, Volk Susan W, Bayat Ardeshir: Regenerative healing, scar-free healing and scar formation across the species: current concepts and future perspectives. Experimental dermatology 23(9): 615-9, Sep 2014.

Volk Susan W, Shah Shalin R, Cohen Arthur J, Wang Yanjian, Brisson Becky K, Vogel Laurie K, Hankenson Kurt D, Adams Sherrill L: Type III collagen regulates osteoblastogenesis and the quantity of trabecular bone. Calcified tissue international 94(6): 621-31, Jun 2014.

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Last updated: 08/06/2018
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