Kristina Cole

faculty photo
Assistant Professor of Pediatrics at the Children's Hospital of Philadelphia
Department: Pediatrics

Contact information
The Children's Hospital of Philadelphia
Colket Translational Research Building, Room 3054
3501 Civic Center Boulevard
Philadelphia, PA 19104
Education:
BS (Chemistry)
Dickinson College, 1992.
PhD (Pathology)
University of Maryland, 1999.
MD (Medicine)
University of Maryland, 2001.
Permanent link
 

Description of Itmat Expertise

Identification of therapeutic targets in pediatric cancer.

Selected Publications

Shuen AY, Lanni S , B. Panigrahi, Edwards M, Yu L, Campbell BB, Mandel A, Zhang C, Nataliya Zhukova N, Alharbi M, Nisreen Amayiri N, Mark Bernstein M, Berry S, Alberto Broniscer A, Bowers D, Carroll S, Cole KA, Constantini S, Crooks B, Rina Dvir R, Farah R, Hijiya N, George B, Laetsch TW, Larouche V, Lindhorst S, Luiten RC, Magimairajan V, Mason G, Mason W, Mordechai O, Mushtaq N, Nicholas G, Oren M, Palma L, Pedroza LA, Rapp J, Ramdas J, Samuel D, Schneider KW, Seeley A, Semotiuk K, Shamvil A, Sumerauer D, Toledano H, Tomboc P, Wierman M, Van Damme A, Lee Y, Zapotocky M, Zorzi A, Bouffet E, Durno C, Andrew SE, Aronson M, Gallinger S, Foulkes WD, Malkin D, Tabori U and Pearson CE: A functional repair assay for the diagnosis of constitutional mismatch repair deficiency from non-neoplastic tissue. J Clinical Oncology in press 2018.

Capasso M, McDaniel LD, Cimmino F, Cirino A, Formicola D, Russell MR, Raman P, Cole KA, Diskin SJ: The functional variant rs34330 of CDKN1B is associated with risk of neuroblastoma. J Cell Mol Med 21(12): 3224-3230, December 2017.

Campbell B, Light N, Fabrizio D, Zatzman M, Fuligni F, de Borja R, Davidson S, Edwards M, Elvin JA, Hodel KP, Zahurancik WJ, Suo Z, Lipman T, Wimmer W, Kratz CP, Bowers DC, Laetsch TW, Dunn GP, Johanns TM, Grimmer MR, Smirnov IV, Larouche V, Samuel D, Bronsema A, Osborn M, Stearns D, Raman P, Cole KA, Storm PB, Yalon M, Opocher E, Mason G, Thomas GA, Sabel M, George B, Ziegler DS, Lindhorst S, Issai VM, Constantini Si, Toledano H, Elhasid R, Farah R, Dvir R, Dirks P, Huang A, Galati MA, Chung J, Ramaswamy V, Irwin MS, Aronson M, Durno C, Taylor MD, Rechavi G, Maris JM, Bouffet E, Hawkins C, Costello JF, Meyn MS, Pursell ZF, Malkin D, Tabori U, Shlien A: Comprehensive Analysis of Hypermutation in Human Cancer. Cell 171(5): 1042-1056, November 2017.

Hart LS, Rader J, Raman P, Batra V, Russell MR, Tsang M, Gagliardi M, Chen L, Martinez D, Li Y, Wood A, Kim S, Parasuraman S, Delach S, Cole KA, Krupa S, Boehm M, Peters M, Caponigro G, Maris JM: Preclinical Therapeutic Synergy of MEK1/2 and CDK4/6 Inhibition in Neuroblastoma. Cancer Res 23(7): 1785-1796, April 2017.

Shah AC, Minturn JE, Li Y, Belasco JB, Phillips PC, Kang TI, Cole KA, Waanders AJ, Pollack R, Didomenico C, Wildes C, Fisher MJ: Carboplatin Rechallenge After Hypersensitivity Reactions in Pediatric Patients with Low-Grade Glioma. Pediatr Blood Cancer 63(1): 21-6, January 2016.

Russell M, Penikis A, Oldridge D, Alvarez-Dominguez J, McDaniel L, Diamond M, Padovan O, Raman P, Li Y, Wei J, Gnanachandran J, Zhang S, Seeger R, Asgharzadeh S, Khan J, Diskin S, Maris JM, Cole KA: CASC15-S is a tumor suppressor lncRNA at the 6p22 neuroblastoma susceptibility locus. Cancer Res 75(15): 3155-66, August 2015.

Tamhankar M, Paessler M, Kharlip J, Shekdar K, Burnham J and Cole K: A 16-year-old boy with a suprasellar mass. J Neuroophthalmol 34(3): 295-300, September 2014.

de Blank P, Cole K, Kersun L, Green A, Wilkes J, Belasco J, Bagatell R, Bailey L, Fisher M: FDG-PET in two cases of neurofibromatosis type 1 and atypical malignancies. Curr Oncol 21(2): 345–8, April 2014.

Khanna A, Kauko O, Bockelman C, Laine A, Schreck I, Partanen JI, Szwajda A, Bormann S, Bilgen T, Helenius M, Pokharel YR, Pimanda JE, Russel MR, Haglund C, Cole KA, Klefstrom J, Aittokallio T, Weiss C, Ristimaki A, Visakorpi T, Westermarck J: Chk1 targeting reactivates PP2A tumor suppressor activity in cancer cells. Cancer Res 73(22): 6757-69, November 2013 Notes: doi: 10.1158/0008-5472.CAN-13-1002. Epub 2013 Sep 26.

Rader J, Russell MR, Hart LS, Nakazawa MS, Belcastro LT, Martinez D, Li Y, Carpenter EL, Attiyeh EF, Diskin SJ, Kim S, Parasuraman S, Caponigro G, Schnepp RW, Wood AC, Pawel B, Cole KA, Maris JM: Dual CDK4/CDK6 inhibition induces cell-cycle arrest and senescence in neuroblastoma. Clin Cancer Res 19(22): 6173-82, November 2013.

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Last updated: 10/15/2018
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