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- Pharmacology Research
- Neurodegeneration (amyloidogenesis, Alzheimer's disease, oxidative stress)
- Infectious disease (antibiotics, antimicrobial peptides,
antibiotic resistance, vancomycin)
- Cardiovascular disease (lipoprotein structure and function)
- Focus Areas
- Mechanisms and consequences of oxidative lipid membrane damage
- Protein-lipid interactions (involved in protein folding, misfolding, and amyloidogenesis)
- Rational drug design and molecular recognition
- Core Technologies
- Mass spectrometry (electrospray, triple-quadrupole, ion trap)
- Computational chemistry (molecular simulation, molecular graphics)
- Infrared spectroscopy (internal reflection, supported monolayers, 2D-IR-COSY)
- Fluorescence spectroscopy (steady state, time resolved)
- Clinical Pharmacology
- Infectious Diseases, Internal and Emergency Medicine
- Adverse drug reactions, drug-drug interactions, pharmacokinetics
(opioid narcotics, psychoactive agents, antibiotics, antiviral & HIV drugs, antiinflammatory agents, cardiovascular and antihypertensive agents)
- Clinicopathological correlation
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Paul H. Axelsen MD
1009C Stellar Chance Labs
University of Pennsylvania
422 Curie Boulevard
Philadelphia, PA 19104-6084
Office: 215-898-9238
Lab: 215-898-9766 |
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