Clinical Assessment Interview for Negative Symptoms (CAINS)

On behalf of the Collaboration to Advance Negative Symptom Assessment in Schizophrenia, thank you for expressing interest in the Clinical Assessment Interview for Negative Symptoms (CAINS). The CANSAS investigators are pleased to disseminate the training for the CAINS instrument to be used in other research projects and for clinical purposes; sharing this type of information is a basic part of furthering scientific knowledge. Our goal in this endeavor is to facilitate research and further clarify the understanding of negative symptoms in schizophrenia. Please note that the CAINS is copyrighted and is for research and clinical purposes in academic, industrial and clinical settings; however, it is not for commercial use.

Before providing access to the CAINS training materials, we ask that you complete the form on the next page. In addition, we ask that you provide assurance that:

  • You are a qualified investigator, or working with a qualified investigator, or a clinician;
  • Your studies will be conducted with approval of an Institutional Review Board, or similar regulatory body, and with oversight for protection of human participants. You will be asked to affirm this when completing the request form;
  • Any publications generated from studies using the CAINS reference their origin. Specific citation information is provided below and should be consulted as you prepare your manuscript or presentation. Once published, we would appreciate receiving reprints of any publications using the CAINS.
Citations for Publications
  • Forbes, C., Blanchard J.J., Bennett, M., Horan, W.P., Kring, A.M., Gur, R.E. (2010). Initial Development and Preliminary Validation of a New Negative Symptom Measure: The Clinical Assessment Inventory for Negative Symptoms. Schizophrenia Research, 124, 36-42.
  • Blanchard, J.J., Kring, A.M., Horan, W.P., Gur, R.E. (2011). Toward the Next Generation of Negative Symptom Assessments: The Collaboration for the Advancement of Negative Symptom Assessment in Schizophrenia. Schizophrenia Bulletin, 37, 291-299.
  • Horan, W.P., Kring, A.M., Gur, R.E., Reise, S.P., Blanchard, J.J. (2011). Development and Psychometric Validation of the Clinical Assessment Interview for Negative Symptoms (CAINS). Schizophrenia Research, 132, 140-145.
  • Kring, A. M., Gur, R. E., Blanchard, J. J., Horan, W. P., Reise, S. P., & (2013). The Clinical Assessment Interview for Negative Symptoms (CAINS): Final development and validation. American Journal of Psychiatry, 170, 165-172.

Our research team will review all requests. Please note that the review process will take approximately 2 weeks. We will contact you when the review is complete. Upon approval of your request, we will provide:

  • Account access to view the training online
  • The training manual, instrument (PDF), gold standard ratings (excel)
  • Note that the manual and instrument may also be obtained from one of the CANSAS investigators (email addresses below).
  • If a translation is planned please let us know so we can inform you if the CAINS is already translated to the language of interest and recommend methodological standards.

Except in established collaborations, we cannot provide any additional support. Specifically, we will not assume responsibility for:

  • Analysis of data produced by our scale;
  • Integrity of individual studies conducted with our materials but outside of our laboratory;
  • Interpretation of results.

Again, thank you for expressing interest in the CAINS instrument. If these conditions are acceptable, please click on the button below that says "I Agree", and fill out the following form. We can then proceed with our review process. Should you have further questions or requests, please contact us via email (

Best regards,

The CANSAS Investigators
Jack Blanchard , Ph.D., University of Maryland
Raquel E. Gur , M.D., Ph.D., University of Pennsylvania
William Horan , Ph.D., University of California, Los Angeles
Ann Kring , Ph.D, University of California, Berkeley

I will not provide the access code or ratings to other individuals beyond my immediate team. Please click on "I Agree" request access to download the training materials and videos.

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