Cell & Molecular Biology Graduate Group


Epigenetics, Gene Regulatory Networks & Signal Integration

The following DSRB laboratories are interested in Epigenetics, Gene regulatory networks and Signal integration:

Montserrat Anguera Roles of long noncoding RNAs during early development and how their misregulation contributes to disease
Marisa Bartolomei The research in my laboratory focuses on the study of genomic imprinting and X inactivation in mice.
Maya Capelson Nuclear structure and its role in gene regulation; Spatial organization of the genome; Epigenetic memory of gene expression states
E. Bryan Crenshaw Analysis of the role of developmental regulatory factors during mouse embryogenesis.
Jonathan Epstein Transcriptional regulation of cardiac development and function using mouse models
Paul Gadue My laboratory studies cell fate decisions, focusing on endoderm and mesoderm specification using mouse and human embryonic stem (ES) cells and induced pluripotent stem (iPS) cells.
Rajan Jain Nuclear architecture, nuclear lamina, chromatin, epigenetics, genome organization, heart development, stem cell biology
Peter Klein Early vertebrate development and pattern formation, Wnt signaling, chromatin and epigenetic regulation of early development, hematopoietic stem cell biology, neural stem cells and neurogenesis, neuropharmacology of bipolar disorder, lithium and glycogen synthase kinase-3 (GSK-3).
Christopher Lengner The overarching goal of my research program is to gain an understanding of the molecular mechanisms that govern stem cell potency and how dysregulation of these mechanisms can contribute to disease onset and progression, including oncogenesis.
Sarah Millar Development of hair follicles, mammary glands, taste papillae and teeth; regeneration and neogenesis of hair follicles and teeth; hair follicle, mammary gland and dental stem cells; skin and mammary gland tumorigenesis; microRNA functions in embryonic and postnatal skin and mammary glands; functions of histone deacetylases in skin and hair follicle development and renewal.
Edward Morrisey lung development, cardiac development, vascular development, Wnt signaling, regulation of gene transcription, GATA factors, forkhead factors
Michael Parmacek Transcriptional programs that regulate cardiovascular development
Ling Qin Bone metabolism, stem cell biology, growth plate development, cancer bone metastasis, and signal transduction
Panteleimon Rompolas

Mechanisms of epithelial stem cell fate and plasticity in skin morphogenesis and regeneration.

Patrick Seale Our lab investigates the transcriptional pathways that control the development, differentiation and function of adipose cells in normal development and in obesity.
Nancy Speck Hematopoietic stem cells and leukemia using mouse models
Jeremy Wang Regulation of meiosis, silencing of transposable elements, piRNA biogenesis, DNA recombination, chromosome segregation, DNA double-strand break repair, chromosome synapsis, male infertility in humans.