Lauren Pantalone
Research Coordinator
Computational Biomarker Imaging Group (CBIG)
Center for Biomedical Image Computing & Analytics (CBICA)
Department of Radiology
Perelman School of Medicine
University of Pennsylvania
Richards Labs, Suite 700D
3700 Hamilton Walk
Philadelphia, PA 19104
Email
Educational Qualifications
M.S. in Public Health in Social and Behavioral Sciences, Temple University. Anticipated graduation May 2020
B.S. in Biochemistry, Jefferson University (Philadelphia University). 2014.
Publications
Conferences
• R. Navaratna, A. Gastounioti, M. Hsieh, L. Pantalone, M. Shelanski, E. F. Conant, and D. Kontos, "Associations between mammographic phenotypes and histopathologic features in ductal carcinoma in situ," SPIE Medical Imaging, San Diego, CA, USA, February 16-21, 2019
• A. Gastounioti, M. Hsieh, L. Pantalone, E. F. Conant, and D. Kontos, "Volumetric versus area-based density assessment: comparisons using automated quantitative measurements from a large screening cohort," SPIE Medical Imaging, Houston, TX, USA, February 10-15, 2018.
• Dong Wei, Susan Weinstein, Meng-Kang Hsieh, Lauren Pantalone, Despina Kontos, "Automatic segmentation of fibroglandular tissue in breast MRI using anatomy-driven three-dimensional spatial context," SPIE Medical Imaging, Houston, TX, USA, February 10-15, 2018.
• Nariman Jahani, Eric Cohen, Meng-Kang Hsieh, Susan P. Weinstein, Lauren Pantalone, Christos Davatzikos, Despina Kontos, "Deformable image registration as a tool to improve survival prediction after neoadjuvant chemotherapy for breast cancer: results from the ACRIN 6657/I-SPY-1 trial," Proc. SPIE 10575, Medical Imaging 2018: Computer-Aided Diagnosis, 105752S (27 February 2018); doi: 10.1117/12.2293720
• Dong Wei, Susan Weinstein, Meng-Kang Hsieh, Lauren Pantalone, Mitchell Schnall, Despina Kontos; Three-dimensional whole breast segmentation in sagittal MR images with dense depth field modeling and localized self-adaptation. Proc. SPIE 10133, Medical Imaging 2017: Image Processing, 1013314 (February 24, 2017); doi:10.1117/12.2248626.
• Andrew Oustimov, Aimilia Gastounioti, Meng-Kang Hsieh, Lauren Pantalone, Emily F. Conant, Despina Kontos; Convolutional neural network approach for enhanced capture of breast parenchymal complexity patterns associated with breast cancer risk. Proc. SPIE 10134, Medical Imaging 2017: Computer-Aided Diagnosis, 101340S (March 3, 2017); doi:10.1117/12.2254506.
• Aimilia Gastounioti, Andrew Oustimov, Meng-Kang Hsieh, Lauren Pantalone, Emily F. Conant, Despina Kontos; Mammographic phenotypes of breast cancer risk driven by breast anatomy. Proc. SPIE 10134, Medical Imaging 2017: Computer-Aided Diagnosis, 1013417 (March 3, 2017); doi:10.1117/12.2254630.
Abstracts
• Chitalia, R, Rowland, J, McDonald, E, Pantalone, L, Cohen, E, Gastounioti, A, Thomas, K, Bastiste, R, Feldman, M, Schnall, M, Conant, E, Kontos, D. Radiomic Phenotypes of Tumor Heterogeneity from Pre-Operative DCE-MRI Predicts Breast Cancer Recurrence after 10-Year Follow-Up: Phenotype Discovery and Independent Validation. Radiological Society of North America 2018 Scientific Assembly and Annual Meeting November 25-November 30, 2018. Chicago IL.
• Conant, E, Zuckerman, S, McDonald, E, Weinstein, S, Pantalone, L, Gastounioti, A, Kontos, D, Synnestvedt, M, Schnall, M, Hubbard, R. Six Years of Consecutive, Population-Based Screening with Digital Breast Tomosynthesis: Outcomes by Screening Year and by Screening Round. Radiological Society of North America 2018 Scientific Assembly and Annual Meeting November 25-November 30, 2018. Chicago IL.
• Gastounioti, A, Hsieh, M, Pantalone, L, Cohen, E, Hu, Y, Conant, E, Kontos, D. Volumetric versus Area-based Breast Density Assessment: Comparisons using Fully-Automated Quantitative Measures in a Large Screening Population. Radiological Society of North America 2018 Scientific Assembly and Annual Meeting November 25-November 30, 2018. Chicago IL.
• Gastounioti, Hsieh, M, Pantalone, L, Conant, E, Kontos, D. Fully-Automated Volumetric Breast Density Estimation from Digital Breast Tomosynthesis: A Case-Control Comparison to Area-Based Density Measures from Digital Mammography. Radiological Society of North America 2018 Scientific Assembly and Annual Meeting November 25-November 30, 2018. Chicago IL.
• Jahani, N, Cohen, E, Hsieh, M, Pantalone, L, Weinstein, S, Davatzikos, C, Kontos, D. Longitudinal Investigation of Tumor Heterogeneity in Breast DCE-MRI to Improve Early Response Assessment to Neoadjuvant Chemotherapy for Locally Advanced Breast Cancer: Results from the ACRIN 6657/I-SPY-1 Trial. Radiological Society of North America 2018 Scientific Assembly and Annual Meeting November 25-November 30, 2018. Chicago IL.
• Zuckerman, S, Hubbard, R, McDonald, E, Weinstein, S, Pantalone, L, Synnestvedt, M, Conant, E. Comparison of DM/Tomosynthesis and Synthesized DM/Tomosynthesis False Negative Cancers in a Population-Based Breast Cancer-Screening Program. Radiological Society of North America 2018 Scientific Assembly and Annual Meeting November 25-November 30, 2018. Chicago IL.
• Gastounioti, A, McCarthy, A, Pantalone, L, Synnestvedt, M, Kontos, D, Conant, E. The Effect of Screening Modality and Race on BI-RADS Breast Density in a Large Urban Screening Cohort. Radiological Society of North America 2018 Scientific Assembly and Annual Meeting November 25-November 30, 2018. Chicago IL.
• A. Gastounioti, M. Hsieh, E. Cohen, L. Pantalone, E. F. Conant, and D. Kontos, "Incorporating breast anatomy in radiomic machine learning for breast cancer risk estimation with digital mammograms," 30th Anniversary AACR Special Conference on Convergence: Artificial Intelligence, Big Data, and Prediction in Cancer, Newport, RI, USA, October 14-17, 2018
• Kontos, D, Winham, S, Oustimov, A, Pantalone, L, Hsieh, M, Gastounioti, A, Whaley, D, Hruska, C, Kerlikowske, K, Brandt, K, Conant, E, Vachon, C. Intrinsic Phenotypes of Breast Parenchymal Complexity: Implications Beyond Mammographic Density in Breast Cancer Risk Assessment. Radiological Society of North America 2017 Scientific Assembly and Annual Meeting November 26-December1, 2017. Chicago IL.
• Kontos, D, McDonald, E, Hsieh, M, Cohen, E, Chitalia, R, Jahani, N, Weinstein, S, Pantalone, L, Newitt, D, Hylton, N, DeMichele, A, Davatzikos, C. Phenotypic Biomarkers of Intra-Tumor Heterogeneity in Breast DCE-MRI Can Augment Tumor Volume Measures in Predicting Survival after Results from the ACRIN 6657/I-SPY-1 Trial. Radiological Society of North America 2017 Scientific Assembly and Annual Meeting November 26-December1, 2017. Chicago IL.
• Gastounioti, A, Hsieh, M, Pantalone, L, Cohen, E, Conant, E, Kontos, D. Standard-Dose versus Synthetic Digital Mammograms: Are There Differences in Automated Measurements of Breast Parenchymal Patterns? Radiological Society of North America 2017 Scientific Assembly and Annual Meeting November 26-December1, 2017. Chicago IL.
• Chitalia R, Rowland J, McDonald E, Pantalone L, Cohen E, Gastounioti A, Thomas K, et al. "Radiomic phenotypes of tumor heterogeneity from pre-operative DCE-MRI independently predict breast cancer recurrence after 10-year follow-up from primary invasive diagnosis." San Antonio Breast Cancer Symposium; Dec 5–9 2017; San Antonio, Texas.
• A. Gastounioti, E. Cohen, L. Pantalone, M. Hsieh, E.F. Conant, D. Kontos, "Associations of dense and fatty breast-tissue complexity with breast cancer risk: Preliminary evaluation using imaging biomarkers driven by breast morphology,” 2017 International Cancer Screening Network (ICSN) Meeting, Bethesda, MD, USA, June 19-21, 2017.
• A. Gastounioti, M. Hsieh, L. Pantalone, E.F. Conant, D. Kontos, "LIBRA: The Laboratory for Individualized Breast Radiodensity Assessment," 8th International Workshop on Breast Densitometry and Cancer Risk Assessment, San Francisco, CA, June 7-9, 2017.
• Brandt, K, Hsieh, M, Scott, C, Pantalone, L, Jensen, M, Winham, S, Whaley, D, Hruska, C, Wu, F, Norman, A, Pankratz, V, Oustimov, A, Conant, E, Kerlikowske, K, Kontos, D, Vachon, C. Validation Study of the Publically-Available Fully Automated “LIBRA” Software for Mammographic Density Estimation: Results from a Case-Control Study of Breast Cancer. Radiological Society of North America 2016 Scientific Assembly and Annual Meeting November 27-December 2, 2016, Chicago IL.
• Chen, L, Pantalone, L, Oustimov, A, Hsieh, M, Conant, E, Kontos, D. Parenchymal Pattern Analysis in Digital Mammograms versus Central Source Projection Tomosynthesis Images: A Case-Control Study for Breast Cancer Risk Estimation. Radiological Society of North America 2016 Scientific Assembly and Annual Meeting November 27-December 2, 2016, Chicago IL.
• Oustimov, A, Gastounioti, A, Hsieh, M, Pantalone, L, Conant, E, Kontos, D. Leveraging “Deep Learning” Methods to Elucidate and Incorporate Novel Breast Parenchymal Complexity Phenotypes to Enhance Breast Cancer Risk Assessment. Radiological Society of North America 2016 Scientific Assembly and Annual Meeting November 27-December 2, 2016, Chicago IL.
• Rowland, J, McDonald, E, Pantalone, L, Oustimov, A, Batiste, R, Thomas, K, Feldman, M, Schnall, M, Conant, E, Kontos, D. Pre-operative MRI Predicts Recurrence after Primary Invasive Breast Cancer Diagnosis Independently of Histopathology: Results from 10 Years of Follow-up of a Multi-Modality Imaging Trial Cohort. Radiological Society of North America 2016 Scientific Assembly and Annual Meeting November 27-December 2, 2016, Chicago IL.
• Conant, E, Oustimov, A, Pantalone, L, Weinstein, S, McDonald, E, Synnestvedt, M, Schnall, M. Three Consecutive Years of Screening with Digital Breast Tomosynthesis: Are the Outcomes Sustainable? Radiological Society of North America 2015 Scientific Assembly and Annual Meeting, November 29 - December 4, 2015, Chicago IL.
• Wu, J, Weinstein, S, Oustimov, A, Pantalone, L, Yu, N, Ou, Y, Rosen, M, DeMichele, A, Davatzikos, C, Kontos, D. Tumor Heterogeneity Patterns on DCE-MRI Parametric Response Maps May Augment Early Assessment of Neoadjuvant Chemotherapy in Locally Advanced Breast Cancer: A Pilot Study of ACRIN 6657/I-SPY 1. Radiological Society of North America 2015 Scientific Assembly and Annual Meeting, November 29 - December 4, 2015, Chicago IL.
• Oustimov, A, Conant, E, Pantalone, L, Keller, B, Hsieh, M, Kontos, D. Prediction of False-Negative Breast Cancer Screens with Digital Mammography: Preliminary evaluation of a Quantitative Breast Complexity Index. Radiological Society of North America 2015 Scientific Assembly and Annual Meeting, November 29 - December 4, 2015, Chicago IL.
• Keller, B, Chen, J, Pantalone, L, Ray, S, Synnestvedt, M, Conant, E, Kontos, D. Agreement between Breast Density Estimates from Standard versus Synthetic Digital Mammograms. Radiological Society of North America 2015 Scientific Assembly and Annual Meeting, November 29 - December 4, 2015, Chicago IL.
• Gastounioti, A, Keller, B, Pantalone, L, Hsieh, M, Oustimov, A, Conant, E, Kontos, D. Associations of Dense and Fatty Breast-Tissue Heterogeneity with Breast Cancer Risk: Preliminary Evaluation Using Parenchymal Texture Measurements Driven by Breast Anatomy. Radiological Society of North America 2015 Scientific Assembly and Annual Meeting, November 29 - December 4, 2015, Chicago IL.