Penn Center for AIDS Research

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Clinical Core

Ian Frank, M.D.

Ian Frank, M.D.
Director, Clinical Core
 franki@pennmedicine.upenn.edu
 215-662-7419

Website


Vincent Lo Re III, M.D., MSCE

Vincent Lo Re III, M.D., MSCE
Co-Director, Clinical Core
 vincentl@pennmedicine.upenn.edu
 215-573-5964

Website


Elizabeth Lowenthal, M.D., MSCE

Elizabeth Lowenthal, M.D., MSCE
Co-Director at CHOP, Clinical Core
 lowenthale@email.chop.edu
 267-426-2306

Website


The mission of the Penn CFAR Clinical Core is to promote and support patient-oriented research related to HIV infection and its co-morbidities.

The Clinical Core maintains longitudinal Adult/Adolescent and Pediatric Databases that include information on over 3,100 HIV-infected men, women, adolescents, and children receiving care in University of Pennsylvania affiliated hospitals. These databases contain patient demographics, clinical and therapeutic information, and behavioral and psychosocial data. Data on adults can be linked to the University of Pennsylvania Data Store, which contains diagnoses, medication lists, laboratory and radiology test results, procedures, and healthcare utilization data from all inpatient and outpatient encounters within the University of Pennsylvania Health System. The CFAR Databases can be linked to Adult/Adolescent and Pediatric Repositories that contain stored plasma, serum and cells. Additional types of patient specimens can be collected by request.

These resources are available to promote interdisciplinary and translational HIV research across the University of Pennsylvania, Children's Hospital of Philadelphia, and Wistar Institute campus, and also are available to non-Penn CFAR members.

Notable Services

To request Clinical Core Services, please complete the Query Request Form. Questions concerning guidance in competing the form should be directed to:
Debbie Gudonis
Clinical Core Research Coordinator 
Email: Debbie.Gudonis@uphs.upenn.edu 
Phone: 215-360-0470

Questions concerning study design or availability of services should be directed to Ian Frank, Director, Clinical Core or Vin Lo Re, Co-Director, Clinical Core.

The Penn AIDS Clinical Trials Unit (ACTU) carries out clinical trials studying new treatments against HIV infection, AIDS, and AIDS-related opportunistic infections. For additional information regarding current studies conducted by the Penn ACTU, visit the AIDS Clinical Trials Unit (ACTU) website.
 


Database Access

The Clinical Core provides access to CFAR investigators who want to directly query the Database and Specimen Repository either in preparation for research (e.g., to check for the availability of specimens in the Adult/Adolescent Specimen Repository with specified characteristics) or the carry out retrospective studies with existing data. 

To access the database please follow the steps below:

1. Please contact Amy Onorato to receive a username and password.

2. Once your username and password have been received, Click here to access the database

3. Review the FAQ sheet for instructions on accessing and utilizing the data.

If you require a more complex query than you can perform on your own or need more guidance in accessing the data, please complete the Query Request Form. Questions concerning guidance in completing the form should be directed to Debbie Gudonis, Clinical Core Research Coordinator. Questions concerning study design or availability of services should be directed to Ian Frank, Director, Clinical Core or Vin Lo Re, Co-Director, Clinical Core.


Specimen Repository Access, Procurement of Fresh Specimens, Consultations, & Specimen Processing and Storage

The Clinical Core provides access to CFAR investigators who want to directly query the Database and Specimen Repository either in preparation for research (e.g., to check for the availability of specimens in the Adult/Adolescent Specimen Repository with specified characteristics) or the carry out retrospective studies with existing data. Click here to access the database. Please contact Amy Onorato to receive a username and password. 

If you require a more complex query than you can perform on your own or need more guidance in accessing the data, please complete the Query Request Form. Questions concerning guidance in completing the form should be directed to Debbie Gudonis, Clinical Core Research Coordinator. Questions concerning study design or availability of services should be directed to Ian Frank, Director, Clinical Core, or Liz Lowenthal & Vin Lo Re, Co-Directors of the Clinical Core. Questions specifically about the pediatric repository should be directed to Liz Lowenthal or Richard Tustin.


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