Partner Research Centers:


Center for Neurodegenerative Disease Research

CNDR 2018 Marian S. Ware Research Retreat

"The Molecular Biology of Aging and Neurodegeneration"

Thursday, October 25, 2018
8:30am — 4:30pm
Biomedical Research Building II/III Lobby and Auditorium
421 Curie Blvd, Philadelphia, PA 19104

 

 

 


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2018 Retreat Speakers

2018 Retreat Speakers:

  • Laura Ranum, PhD
  • Leeanne McGurk, PhD
  • Silvia Porta, PhD
  • Lin Guo, PhD
  • Shuying Sun, PhD
  • Rafaella Nativio, PhD
  • Jennifer Phillips-Cremins, PhD
  • Joshua Dubnau, PhD

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Agenda

8:30 AM

CONTINENTAL BREAKFAST & CHECK-IN

8:50 AM

WELCOME AND OVERVIEW

9:00 AM

Laura Ranum, PhD
University of Florida
"Targeting RAN proteins improves phenotypes in C9orf72 BAC ALS/FTD mice"

9:50 AM

Leeanne McGurk, PhD
University of Pennsylvania
"Poly (ADP-Ribose) Prevents Pathological Phase Separation of TDP-43 by Promoting Liquid
Demixing and Stress Granule Localization"

10:10 AM

Silvia Porta, PhD
University of Pennsylvania
"Patient-derived Frontotemporal Degeneration Brain Extracts Induce Formation and Spreading
of TDP-43 Pathology in vivo"

10:30 AM

BREAK

11:00 AM

Lin Guo, PhD
University of Pennsylvania
"Kapβ2 Reverses Aberrant Phase Transitions of ALS-linked Disease Proteins"

11:20 AM

Shuying Sun, PhD
Johns Hopkins University
"Understanding the repeat-associated non-AUG translation in C9ORF72-ALS/FTD"

12:10 PM

LUNCH & POSTERS

2:00 PM

Raffaella Nativio, PhD
University of Pennsylvania
"Epigenetic dysregulation in Alzheimer's disease"

2:20 PM

Jennifer Phillips-Cremins, PhD
University of Pennsylvania
"3D genome misfolding in trinucleotide repeat expansion disorders"

3:10 PM

Josh Dubnau, PhD
Stony Brook School of Medicine
"Retrotransposons and TDP-43 mediated neurodegeneration: the dangers of a Collyer's genome"

4:00 PM

WRAP UP & POSTER AWARDS

 

 

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Registration and Poster Submission

This event has passed.

 

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Parking and Directions

For directions to Biomedical Research Building or BRB 2/3, click here.
You can also access parking information at Penn Parking Services.

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Questions?

Questions? Please contact Kevin Davies at 215-662-4474 or daviesk@upenn.edu.

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