Perelman School of Medicine at the University of Pennsylvania

Center for Preventive Ophthalmology and Biostatistics (CPOB)

John Kempen

John KempenJohn H. Kempen, M.D, M.H.S., M.P.H., Ph.D. is Associate Professor of Ophthalmology and Epidemiology, Director of the Ocular Inflammation Service at the Scheie Eye Institute/Department of Ophthalmology, and the Director of Ophthalmic Epidemiology at the Center for Preventive Ophthalmology and Biostatistics. Prior to assuming his current position, he served as Assistant Professor of Ophthalmology and Epidemiology, and as Director of the Public Health Ophthalmology program of the Dana Center for Preventive Ophthalmology, Wilmer Eye Institute/Department of Ophthalmology at the Johns Hopkins University. 

Dr. Kempen an American Board of Ophthalmology-certified Opthalmologist who has doctoral training in epidemiology, and masters-level training in biostatistics and public health.  He has completed research fellowships in clinical trials and in preventive ophthalmology.  He is a fellow of the American Academy of Ophthalmology, and a member of the American Uveitis Society, the International Uveitis Study Group, the Society for Clinical Trials, and the Association for Research in Vision and Ophthalmology.  He was appointed by President Bush to serve as a member of the Office of AIDS Research Advisory Council (2004-2008), and has numerous publications in the leading journals of his specialty.

Dr. Kempen has extensive experience in large-scale prospective and retrospective cohort studies and clinical trials.  He is Principal Investigator of the Systemic Immunosuppressive Therapy for Eye Diseases (SITE) Cohort Study, a multicenter study of approximately 10,000 patients with inflammatory eye diseases followed for up to 25 years for mortality using National Death Index linkage.  He is international vice-chair of the Multicenter Uveitis Steroid Treatment (MUST) trial, a national study comparing fluocinolone acetonide implant therapy to systemic therapy for treatment of intermediate, posterior, and panuveitis.  He served as director of the Johns Hopkins CMV Retinitis Cohort Study for approximately 6 years.  In addition, he has had leadership roles in the Studies of Ocular Complications of AIDS Research Group, a network studying ocular complications of HIV/AIDS for 8 years.  He served as a coordinator for the Eye Diseases Prevalence Research Group, combining data from population-based studies of the prevalence of major blinding eye diseases to generate national prevalence estimates for policy and research applications.  He also served as an epidemiological expert on two major AHRI-funded evidence-based review projects at the Johns Hopkins Evidence-Based Practice Center, regarding anesthesia for cataract surgery and combined surgery for glaucoma and cataract.

In addition to his research activities, Dr. Kempen is a clinically active ophthalmologist who serves as the regional specialist in Ocular Inflammation for the Delaware Valley.

Associate Professor
Phone: 215-662-8155