Department of Psychiatry

Penn Behavioral Health

Key Publications

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Chopra, M.P., Zhang, H., Pless, K.A., Moye, J.A., Llorente, M.D., Oslin, D.W., & Spiro, A.  PTSD is a chronic, fluctuating disorder affecting the mental quality of life in older adults.  The American Journal of Geriatric Psychiatry: Official Journal of the American Association for Geriatric Psychiatry, 22(1):86-97, 2014.

Clarke, T.K., Weiss, A.R., Ferarro, T.N., Kampman, K.M., Dackis, C.A., Pettinati, H.M., O'Brien, C.P., Oslin, D.W., Lohoff, F.W., & Berrettini, W.H.  The dopamine receptor D2 (DRD2) SNP rs1076560 is associated with opioid addiction.  Annals of Human Genetics, 78(1):33-39, 2014.

Gelernter, J., Kranzler, H.R., Sherva, R., Almasy, L., Koesterer, R., Anton, R., Preuss, U.W., Ridinger, M., Rujescu, D., Wodarz, N., Zill, P., Han, S., Zhao, H., & Farrer, L.A.  Genome-wide association study of alcohol dependence: significant findings in African- and European-Americans including novel risk loci.  Molecular Psychiatry, 19:41-49, 2014.

Kranzler, H.R., Armeli, S., Feinn, R., Tennen, H., Gelernter, J., & Covault, J.  GRIK1 genotype moderates topiramate’s effects on daily drinking level, expectations of alcohol’s positive effects, and desire to drink.  International Journal of Neuropsychopharmacology (In Press).

Kranzler, H.R., Covault, J., Feinn, R., Armeli, S., Tennen, T., Arias, A.J., Gelernter, J., Oncken, C., Pond, T., & Kampman, K.M.  Topiramate treatment of heavy drinkers: moderation by a GRIK1 polymorphism.  American Journal of Psychiatry, 171:1-8, 2014.

Langleben, D.D., Ruparel, K., Elman, I., Loughead, J.W., Busch, E.L., Cornish, J., Lynch, K.G., Nuwayser, E.S., Childress, AR., & O'Brien, C.P.  Extended-release naltrexone modulates brain response to drug cues in abstinent heroin-dependent patients.  Addiction Biology, 19(2):262-271, 2014.

Maust, D.T., Oslin, D.W., & Marcus, S.C.  Effect of age on the profile of psychotropic users: results from the 2010 National Ambulatory Medical Care Survey.  Journal of the American Geriatrics Society, 62(2):358-364, 2014.

Oslin, D.W., Lynch, K.G., Maisto, S.A., Lantinga, L.J., McKay, J.R., Possemato, K., Ingram, E., Wierzbicki, M.  A randomized clinical trial of alcohol care management delivered in department of veterans affairs primary care clinics versus specialty addiction treatment.  Journal of General Internal Medicine, 29(1):162-168, 2014.

Wang, Z., Li, Y., Childress, AR., & Detre, J.A.  Brain Entropy Mapping using fMRI.  Plos One, 9(3): e89948, 2014.

Wetherill, R.R., Childress, AR., Jagannathan, K., Bender, J., Young, K.A., Suh, J.J., O’Brien, C.P., & Franklin, T.R.  Neural responses to subliminally presented cannabis and other emotionally evocative cues in cannabis-dependent individuals.  Psychopharmacology, 231(7):1397-1407, 2014.

Wetherill, R.R., Jagannathan, K., Lohoff, F.W., Ehrman, R., O’Brien, C.P., Childress, AR., & Franklin, T.R.  Neural correlates of attentional bias for smoking cues: modulation by variance in the dopamine transporter gene.  Addiction Biology, 19(2):294-304, 2014.

Wetherill, R.R., Jagannathan, K., Shin, J., & Franklin, T.R.  Sex differences in resting state neural networks of nicotine-dependent cigarette smokers.  Addictive Behaviors, 39(4):789-792, 2014.

Wetherill, R.R., Young, K.A., Jagannathan, K., Shin, J., O’Brien, C.P., Childress, AR., & Franklin, T.R.  The impact of sex on brain responses to smoking cues: a perfusion  fMRI study.  Biology of Sex Differences, 29(4):9, 2014.

Woody, G.E., Bruce, D., Korthuis, T.P., Chhatre, S., Hillhouse, M., Jacobs, P., Sorensen, J., Saxon, A., Poole, S., Metzger, D., & Ling, W.  HIV risk reduction with Buprenorphine-Naloxone or Methadone: findings from a randomized trial.  Journal of Acquired Immune Deficiency Syndrome, 66(3): 288-293, 2014.

Young, K., Franklin, T.R., Roberts, D., Jagannathan, K., Suh, J.J., Wetherill, R.R., Wang, Z., Kampman, K., O’Brien, C.P., & Childress, AR.  Nipping cue reactivity in the bud: Baclofen prevents limbic activation elicited by subliminal drug cues.  Journal of Neuroscience, 34(14): 5038-5043, 2014.
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Chakravorty, S., Grandner, M.A., Kranzler, H.R., Mavandadi, S., Kling, M.A.,
Perlis, M.L., & Oslin, D.W.  Insomnia in alcohol dependence: predictors of symptoms in a sample of veterans referred from primary care.  The American Journal on Addictions/American Academy of Psychiatrists in Alcoholism and Addictions, 22(3):266-270, 2013.

Chakravorty, S., Grandner, M.A., Mavandadi, S., Perlis, M.L., Sturgis, E.B., & Oslin, D.W.  Suicidal ideation in veterans misusing alcohol: relationships with insomnia symptoms and sleep duration.  Addictive Behaviors, 39(2):399-405, 2013.

Clarke, T.K., Crist, R.C., Kampman, K.M., Dackis, C.A., Pettinati, H.M., O'Brien, C.P., Oslin, D.W., Ferraro, T.N., Lohoff, F.W., & Berrettini, W.H.  Low frequency genetic variants in the μ-opioid receptor (OPRM1) affect risk for addiction to heroin and cocaine.  Neuroscience Letters, 542:71-75, 2013.

Crist, R.C., Ambrose-Lanci, L.M., Zeng, A., Yuan, C., Kampman, K.M., Pettinati, H.M., Oslin, D.W., O’Brien, C.P., Ferraro, T.N., Doyle, G.A., Lohoff, F.W., & Berrettini, W.H.  Case-control association study of WLS variants in opioid and cocaine addicted populations.  Psychiatry Research, 208(1):62-66, 2013.

Elkassabany, N., Speck, R.M., Oslin, D.W., Hawn, M., Chaichana, K., Sum-Ping, J., Sepulveda, J., Whitley, M., & Sakawi, Y.  Preoperative screening and case cancellation in cocaine-abusing veterans scheduled for elective surgery.  Anesthesiology Research and Practice 2013: 149892, 2013. doi: 10.1155/2013/149892. Epub 2013 Aug 28.

Foa, E.B., Yusko, D.A., McLean, C.P., Suvak, M.K., Bux, D.A., Oslin, D.W., O'Brien, C.P., Imms, P., Riggs, D.S., & Volpicelli, J.  Concurrent naltrexone and prolonged exposure therapy for patients with comorbid alcohol dependence and PTSD: a randomized clinical trial.  The Journal of the American Medical Association, 310(5):488-495, 2013.

Gelernter, J., Kranzler, H.R., Sherva, R., Koesterer, R., Almasy, L., Zhao, H., & Farrer, L.A.  Genomewide association study of opioid dependence and related traits: multiple associations mapped to calcium and potassium pathways.  Biological Psychiatry, 2013 Oct 19. [Epub ahead of print].

Gelernter, J., Sherva, R., Koesterer, R., Almasy, L., Zhao, H., Kranzler, H.R., & Farrer, L.  Genomewide association study of cocaine dependence and related traits: FAM53B identified as a risk gene.  Molecular Psychiatry, 2013 Aug 20. [Epub ahead of print].

Goldman, M., Szucs-Reed, R.P., Jagannathan, K., Ehrman, R.N., Wang, Z., Li, Y., Suh, J.J., Kampman, K., O’Brien, C.P., Childress, AR., & Franklin, T.R.  Reward-related brain response and craving correlates of marijuana cue exposure: a preliminary study in treatment-seeking marijuana-dependent subjects.  Journal of Addiction Medicine, 7(1):8-16, 2013.

Kampman, K.M., Pettinati, H.M., Lynch, K.G., Spratt, K., Wierzbicki, M.R., & O'Brien, C.P.  A double-blind, placebo-controlled trial of topiramate for the treatment of comorbid cocaine and alcohol dependence.  Drug Alcohol Dependence, 133(1):94-99, 2013.

Kranzler, H.R., Armeli, S., Covault, J., & Tennen, H.  Variation in OPRM1 moderates the effect of desire to drink on subsequent drinking and its attenuation by naltrexone treatment.  Addiction Biology, 18:193-201, 2013.

Kranzler, H.R., Armeli, S., Tennen, H., & Covault, J.  5-HTTLPR genotype and daily negative mood moderate the effects of sertraline on drinking intensity.  Addiction Biology, 18:1024-1031, 2013.

Magland, J.F. & Childress, AR.  Task-correlated facial and head movements in classifier-based real-time fMRI.  Journal of Neuroimaging, 1-8, 2013.

Pecoraro, A., Ewen, E., Horton, T., Mooney, R., Kolm, P., McGraw, P., & Woody, G.E.  Using the AUDIT-PC to predict alcohol withdrawal in hospitalized patients.  Journal of General Internal Medicine, 1-7, 2013.

Pecoraro, A., Fishman, M., Ma, M., Piralishvili, G., & Woody, G. E.  Pharmacologically assisted treatment of opioid-dependent youth.  Pediatric Drugs, 15(6):449-458, 2013.

Pecoraro, A., Royer-Malvestuto, C., Rosenwasser, B., Moore, K., Howell, A., Ma, M., & Woody, G.E.  Factors contributing to dropping out from and returning to HIV treatment in an inner city primary care HIV clinic in the United States. AIDS Care - Psychological and Socio-Medical Aspects of AIDS/HIV, 25(11):1399-1406, 2013. 

Peer, P., Rennert, L., Lynch, K.G., Farrer, F., Gelernter, J., & Kranzler, H.R.  Prevalence of DSM-IV and DSM-5 alcohol, cocaine, opioid, and cannabis use disorder diagnoses in a substance dependent sample.  Drug and Alcohol Dependence, 127:215-219, 2013.

Saxon, A.J., Ling, W., Hillhouse, M., Thomas, C., Hasson, A., Ang, A., et al.  Buprenorphine/Naloxone and methadone effects on laboratory indices of liver health: a randomized trial.  Drug and Alcohol Dependence, 128(1-2):71-76, 2013.

Strobel, B., McManus, L., Leong, S., Blow, F., Slaymaker, V., Berrettini, W., Gordon, A.J., O'Brien, C., Oslin, D.W.  A cross-sectional study of attitudes about the use of genetic testing for clinical care among patients with an alcohol use disorder.  Alcohol and Alcoholism (Oxford, Oxfordshire), 48(6):700-703, 2013.

Wang, A.L., Romer, D., Elman, I., Turetsky, B.I., Gur, R.C., & Langleben, D.D. Emotional graphic cigarette warning labels reduce the electrophysiological brain response to smoking cues.  Addiction Biology, 2013 Dec 15. doi: 10.1111/adb.12117 [Epub ahead of print].

Wang, A.L., Ruparel, K., Loughead, J.W., Strasser, A.A., Blady, S.J., Lynch, K.G., Romer, D., Cappella, J.N., Lerman, C., & Langleben, D.D.  Content matters: neuroimaging investigation of brain and behavioral impact of televised anti-tobacco public service announcements.  Journal of Neuroscience, 33(17):7420-7427, 2013.

Wang, Z., Sandhitsu, R., Das, S., Xie, X., Arnold, S.E., Detre, J.A., & Wolk, D.A. Arterial Spin Labeled MRI in Prodromal Alzheimer’s Disease: A multi-site study.  Neuroimage: Clinical, 2:630–636, 2013.

Woody, G.E. & Crits-Cristoph, P. Individual therapy for substance use disorders.  Gabbard’s Treatments of Psychiatric Disorders, 5th Edition; Ed Glen O. Gabbard, M.D., Arlington, VA, 2013.

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