​​​MouseThe Mouse Cardiovascular Physiology Core provides services to assess cardiovascular function in mouse models and to provide validated surgical models of heart and vascular disease in mice to assess genetic or therapeutic interventions. We will work with investigators to design and implement the study along with any associated grant applications, animal protocol submissions and manuscript preparation. While the central focus of the facility is cardiovascular research, the techniques employed are often useful to investigators in other fields. Our Core staff will work with you to assess your needs and provide the necessary technical training and scientific assistance in animal protocol preparation. The Core runs on a fee-for-service model.  Accordingly, investigators will be responsible for the costs incurred for their projects and prior animal protocol approval by Penn IACUC.




Ling Lai, M.D., Ph.D.Ling Lai

     Director and Cardiac Surgeon
     Phone: 215-898-2656
     Email: linglai@pennmedicine.upenn.edu
     Surgical Suite: Smilow 11-222


Joanna Griffin, MS, RCS, RDCSJoanna

     Rodent Echocardiographer
     Phone: 215-573-3913
     Email: Joanna.Griffin@Pennmedicine.upenn.edu
     Echo Lab: Smilow 11-222


Ingrid Marti Pamies, PhDIngrid

     Mouse Echocardiographer (part-time)
     Email: ingridm@pennmedicine.upenn.edu



Marielle Scherrer-Crosbie, MD, PhDMarielle

     Faculty Core Advisor for Echocardiography
     Email: Marielle.Scherrer-Crosbie@pennmedicine.upenn.edu
     Office: South Pavilion 11-131


Daniel P. Kelly, MDDaniel Kelly

     Faculty Core Advisor for Cardiac Surgery and Physiology
     Email: dankelly@pennmedicine.upenn.edu
     Office: Smilow TRC 11-122




Teresa C. LeoneTeresa

     Associate Director of Scientific Administration and Operations, CVI
     Phone: 215-898-0768
     Email: terleone@pennmedicine.upenn.edu
     Office: Smilow 11-122A



Mouse Core Research


Mouse Core Research

Other services are available upon request.  Please email terleone@pennmedicine.upenn.edu.