Emily Flam, Kenneth Margulies, and Zoltan Arany

Integrated landscape of cardiac metabolism in end-stage human nonischemic dilated cardiomyopathy

Zolt


Senthil Selvaraj and Kenneth Margulies

Metabolomic Profiling of the Effects of Dapagliflozin in Heart Failure with Reduced Ejection Fraction: DEFINE-HF

Senthil and Kenneth


Kristina Li, Shogo Waga, Bridget Gosis, and Zoltan Arany

Folliculin promotes substrate-selective mTORC1 activity by activating RagC to recruit TFE3

Zolt


Yanqing Anna Gong and Yi Fan

Endothelial plasticity drives aberrant vascularization and impedes cardiac repair after myocardial infarction

Gong


Eliot Peyster and Kenneth Margulies

Computational Analysis of Routine Biopsies Improves Diagnosis and Prediction of Cardiac Allograft Vasculopathy

Eliot


Bridget Gosis and Zoltan Arany

Inhibition of nonalcoholic fatty liver disease in mice by selective inhibition of mTORC1

Zolt


Roman Tsaryk and Arndt Siekmann

Shear stress switches the association of endothelial enhancers from ETV/ETS to KLF transcription factor binding sites

Arndt Siekmann


Sharlene Day and Michael Ostap

Myosin modulators: emerging approaches for the treatment of cardiomyopathies and heart failure

Sharlene and Michael


Elvin V. Leonard, Arndt Siekmann

Regenerating vascular mural cells in zebrafish fin blood vessels are not derived from pre-existing mural cells and differentially require Pdgfrb signalling for their development

Siekmann


Daniel Rader

A genome-first approach to rare variants in hypertrophic cardiomyopathy genes MYBPC3 and MYH7 in a medical biobank

Daniel Rader


Daniel Rader

Sortilin restricts secretion of apolipoprotein B-100 by hepatocytes under stressed but not basal conditions

Daniel Rader


Ayon Ibrahim, Michael Neinast, and Kristina Li

Insulin-stimulated adipocytes secrete lactate to promote endothelial fatty acid uptake and transport

Arany Lab


Joel Rurik, Jonathan Epstein, and Hamideh Parhiz

CAR T cells produced in vivo to treat cardiac injury

JR, JE, HP


Zoltan Arany, Benjamin Prosser, and Quentin McAfee

Truncated titin proteins in dilated cardiomyopathy

Zolt


Sharlene Day and Anjali Owens

Valsartan in early-stage hypertrophic cardiomyopathy: a randomized phase 2 trial

Sharlene


Wonho Kim, Ricardo Linares-Saldana, Nikhita Bolar, and Rajan Jain

BRD4 orchestrates genome folding to promote neural crest differentiation

Rajan Jain


Zoltan Arany

Laminar Flow on Endothelial Cells Suppresses eNOS O-GlcNAcylation to Promote eNOS Activity

Zoltan Arany


Steven Keller and Mark Kahn

Genetic blockade of lymphangiogenesis does not impair cardiac function after myocardial infarction

Steven Keller


Zoltan Arany

Thymic stromal lymphopoietin induces adipose loss through sebum hypersecretion

Zoltan Arany


Daniel Rader

Associations of HDL metrics with coronary artery calcium score and density among women traversing menopause

Daniel Rader


Rajat Deo

COVID-19 and Cardiac Arrhythmias

Rajan Deo


Kiran Musunuru

In vivo CRISPR base editing of PCSK9 durability lowers cholesterol in primates

Kiran Musunuru


Senthil Selvaraj

Atrial Fibrillation and Ischemic Stroke with the Amyloidogenic V122I Transthyretin Variant among Black Americans

senthil


Rahul Goli & Zoltan Arany

Genetic and Phenotypic Landscape of Peripartum Cardiomyopathy

Zoltan


Aileen Ren & Mark Kahn

PIK3CA and CCM mutations fuel cavernomas through a cancer-like mechanism

Mark Kahn


Jarod Zepp & Edward Morrisey

Genomic, epigenomic, and biophysical cues controlling the emergence of the lung alveolus

Morrisey


Parisha Shah, Wenjian Lv, Kiran Musunuru, & Rajan Jain

Pathogenic LMNA variants disrupt cardiac lamina-chromatin interactions and de-repress alternative fate genes

All


Rohan Palanki & Michael Mitchell

Delivery technologies for in utero gene therapy

Rohan


John Greenwood & Benjamin Abella

Low Microcirculatory Perfused Vessel Density and High Heterogeneity are Associated with Increased Intensity and Duration of Lactic Acidosis After Cardiac Surgery with Cardiopulmonary Bypass

Greenwood


Sharlene Day

2020 AHA/ACC Guideline for the Diagnosis and Treatment of Patients with Hypertrophic Cardiomyopathy

Day


Jordana Cohen & Julio Chirinos

Continuation versus discontinuation of renin-angiotensin system inhibitors in patients admitted to hospital with COVID-19: a prospective, randomized, open-label, blinded endpoint trial

Chirinos


Timothy Matsuura & Daniel Kelly

Ketone Ester Treatment Improves Cardiac Function and Reduces Pathologic Remodeling in Preclinical Models of Heart Failure

Kelly