Recent CVI Research

Nesrine Bouhrira, Alexia Vite, and Kenneth Margulies

Distinct cytoskeletal regulators of mechanical memory in cardiac fibroblasts and cardiomyocytes

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Igor Makhlin, Biniyam Demissei, Nick Wilcox, and Bonnie Ky

Statins Do Not Significantly Affect Oxidative Nitrosative Stress Biomarkers in the PREVENT Randomized Clinical Trial

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Parisha Shah and Rajan Jain

A genome-wide CRISPR screen identifies BRD4 as a regulator of cardiomyocyte differentiation

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Zoltan Arany

Peripartum Cardiomyopathy

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Zoltan Arany, Boa Kim

Endothelial lipid droplets suppress eNOS to link high fat consumption to blood pressure elevation

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Zoltan Arany, Marc Bornstein

Comprehensive quantification of metabolic flux during acute cold stress in mice

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Zoltan Arany, Benjamin Prosser, Quentin McAfee

Truncated titin protein in dilated cardiomyopathy incorporates into the sarcomere and transmits force

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Tomoya Sakamoto, Daniel Kelly

Cardiac Maturation

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Xiaolong Zhu, Ioana Soaita, Zoltan Arany, and Michael Simons

Acetate controls endothelial-to-mesenchymal transition

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Daniel Baker, Zoltan Arany, Joseph Baur, Jonathan Epstein, and Carl June

CAR T therapy beyond cancer: the evolution of a living drug

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Sharlene Day, Marcus Wagner, and Andrea Thompson

An Unbiased Screen Identified the Hsp70-BAG3 Complex as a Regulator of Myosin-Binding Protein C3

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Kiran Musunuru, Dominique Brooks, Mohamad-Gabriel Alameh, and Xiao Wang

Rapid and definitive treatment of phenylketonuria in variant-humanized mice with corrective editing

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Megan Blair and Zoltan Arany

Branched-chain amino acid catabolism in muscle affects systemic BCAA levels but not insulin resistance

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Elvin Leonard and Arndt Siekmann

Temporally and regionally distinct morphogenetic processes govern zebrafish caudal fin blood vessel network expansion

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Timothy Matsuura, Daniel Kelly

Ketones and the Heart: Metabolic Principles and Therapeutic Implications

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Tsunehisa Yamamoto, Daniel Kelly, Mitchell Lazar

RIP140 Deficiency Enhances Cardiac Fuel Metabolism and Protects Mice from Heart Failure

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Amy Lisanti

Developmental Care for Hospitalized Infants With Complex Congenital Heart Disease: A Science Advisory From the American Heart Association

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Jennifer Lewey

Challenges and opportunities to improving research in maternal cardiovascular health

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Parisha Shah and Rajan Jain

An atlas of lamina-associated chromatin across twelve human cell types reveals an intermediate chromatin subtype

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Estibaliz Castillero, Giovanni Ferrari, and Robert Levy

Decreased serotonin transporter activity in the mitral valve contributes to progression of degenerative mitral regurgitation

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David Frank, Prashant Chandrasekaran, and Nicholas Negretti

CXCL12 defines lung endothelial heterogeneity and promotes distal vascular growth

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Emily Flam, Kenneth Margulies, and Zoltan Arany

Integrated landscape of cardiac metabolism in end-stage human nonischemic dilated cardiomyopathy

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Senthil Selvaraj and Kenneth Margulies

Metabolomic Profiling of the Effects of Dapagliflozin in Heart Failure with Reduced Ejection Fraction: DEFINE-HF

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Kristina Li, Shogo Waga, Bridget Gosis, and Zoltan Arany

Folliculin promotes substrate-selective mTORC1 activity by activating RagC to recruit TFE3

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Yanqing Anna Gong and Yi Fan

Endothelial plasticity drives aberrant vascularization and impedes cardiac repair after myocardial infarction

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Eliot Peyster and Kenneth Margulies

Computational Analysis of Routine Biopsies Improves Diagnosis and Prediction of Cardiac Allograft Vasculopathy

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Bridget Gosis and Zoltan Arany

Inhibition of nonalcoholic fatty liver disease in mice by selective inhibition of mTORC1

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Roman Tsaryk and Arndt Siekmann

Shear stress switches the association of endothelial enhancers from ETV/ETS to KLF transcription factor binding sites

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Sharlene Day and Michael Ostap

Myosin modulators: emerging approaches for the treatment of cardiomyopathies and heart failure

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Elvin V. Leonard, Arndt Siekmann

Regenerating vascular mural cells in zebrafish fin blood vessels are not derived from pre-existing mural cells and differentially require Pdgfrb signalling for their development

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