Ignore This Picture

GI Cancer Risk Evaluation Program (GI CREP)

Download the NEW PATIENT PACKET here.

Once you have completed the NEW PATIENT PACKET to the best of your ability, please return via:
Email (preferred): GIGenetics@uphs.upenn.edu or
Fax:215-349-5314 (Attn: GI CREP)

Download Frequently Asked Questions sheet here.

Attending Gastroenterologists:
Anil Rustgi, MD
Bryson Katona, MD, PhD
Kirk Wangensteen, MD, PhD

Genetic Counselors:
Amanda Brandt, MS, LCGC
Dana Clark, MS, MS, LCGC
Danielle McKenna, MS, LCGC
Jessica Long, MS, LCGC
Jacquelyn Powers, MS, LCGC

The GI Cancer Risk Evaluation Program (GI-CREP) offers information, evaluation, and follow-up for people who are at increased risk to develop gastrointestinal cancer due to a personal or family history of colon polyps, colon cancer or other gastrointestinal cancers (pancreatic, stomach, esophageal, liver). It is also important to note that a personal or family history of genitourinary cancers, such as ovarian, bladder, kidney, and uterine cancer, may contribute to an individuals risk of assessment.

Although most cancers happen by chance and occur at older ages, you may have an inherited risk of cancer in a family if you have:

  • Multiple relatives with the same type of cancer
  • Early age of diagnosis of colon polyps or colon cancer or another gastrointestinal cancer
  • Multiple relatives with colon polyps
  • Multiple relatives with different forms of cancer
  • Individuals who have more than one form of cancer

Penn's GI Cancer Risk Evaluation Program offers a team of experts in gastrointestinal medicine who are nationally recognized experts in the diagnosis and treatment of colon and other gastrointestinal cancers.  Our genetic counselors also have extensive experience in family history assessment, education and counseling for people with a personal/family history of cancer. During your initial visit our specialists help answer questions such as:

  • What is my level of risk for developing gastrointestinal cancer?
  • How can I protect myself?
  • What about my family members?
  • Would testing for the inherited forms of cancer be helpful?

Our specialists provide:

  • A review of your medical history
  • A physical examination and additional testing, as needed
  • Genetic counseling and genetic testing, when appropriate
  • Discussion of your personal risk and recommended risk-reduction strategies
  • A plan for ongoing monitoring for early detection and personal risk reduction


University of Pennsylvania | Perelman School of Medicine