Graduate Group in Genomics and Computational Biology

GCB Home » Faculty » Functional genomics

  Name Research
Yoseph Barash The lab develops machine learning algorithms that integrate high-throughput data (RNASeq, CLIPSeq , PIPSeq, etc.) to infer RNA biogenesis and function, followed by
experimental verifications of inferred mechanisms.
Roberto Bonasio Non-coding RNAs and regulation of gene expression
Dustin Brisson The effects of genomic variation in microbial pathogen populations on infectivity and invasiveness
Casey Brown Our research focuses on how genotypes produce phenotypes and how they vary and evolve.
Maja Bucan Genetic dissection of complex behaviors in mice and human; Functional genomics, Bipolar disorder, Autism
Rick Bushman Gene therapy for human diseases
Russ Carstens Study of the molecular mechanisms of alternative splicing. Identification of global
changes in splicing during the epithelial-mesenchymal transition (EMT).
Sara Cherry Genetic and mechanistic studies of viral-host interactions
Lewis Chodosh Genetically engineered mouse models for breast cancer initiation, metastasis, and recurrence. Normal developmental biology of the mammary gland. Tumor dormancy. Stem cells in breast cancer and mammary development. Oncogenes and tumor suppressors in breast cancer. Genomics and computational biology. Non-invasive imaging
Jennifer Phillips-Cremins
Epigenetics | Genomics | Systems and Synthetic Bioengineering | Experimental Neuroscience | Molecular and Cellular Engineering
Scott Diamond Dr. Diamond researches biotechnologies in several key areas: endothelial mechanobiology, blood clot dissolving therapies, blood systems biology, nonviral gene therapy, and high
throughput drug discovery.
James Eberwine Molecular basis of neuronal adaptation with emphasis on the following adaptive processes; tetanic potentiation, glucocorticoid-induced, age-induced as well as opiate-induced adaptation
Beverly Emanuel I am a human geneticist investigating several diseases caused by abnormalities of human chromosomes, particularly chromosome 22.
Robert Babak Faryabi

With the help of computational biology, we investigate the role of epigenetic dysregulation in development and maintenance of lymphomagenesis.

Casey Greene Tissue-specific effects of variants across multiple phenotypes.
Brian Gregory Mechanisms and regulation of RNA silencing pathways
Elizabeth Grice Microbial regulation of host/skin gene expression
Blanca Himes Identification of transcript expression signatures associated with chronic pulmonary diseases and their treatment outcomes.
Qihong Huang 1) Functional genomics in metastasis
2) Non-coding RNA in tumor development
and metastasis
3) Selective chemotherapies
Klaus Kaestner Integrative analsysis of epigenomic datasets for the study of diabetes and colon cancer
Junhyong Kim Single cell genomics, systems biology of cell function, evolution of cell function, population genetics and phylogenetics
Mitch Lazar Epigenomic regulation of transcription and metabolism by nuclear receptors; mechanism
of obesity-associated insulin resistance and diabetes; circadian regulation of metabolism
Timothy Linksvayer The molecular basis of complex
social systems
John Maris Dr. Maris's research focuses on translational genomics and genetics of neuroblastoma.
John Murray Defining developmental regulatory networks and mechanisms
Kate Nathanson Evaluating functional variation in regards to loci associated with susceptibilty to testicular germ cell tumors
Allan Pack Dr. Pack is pursuing research on genetics/genomics of sleep and its disorders. His laboratory is conducting studies in Drosophila and mice and translating these
findings to humans.
Scott Poethig Genetic regulation of the juvenile-to-adult transition in plants. The developmental function of RNAi in plants
David Roos Studies in the Roos laboratory employ modern cell biological, molecular genetic, biochemical/pharmacological, immunological and genomic/bioinformatic techniques to study protozoan parasites, eukaryotic evolution, and the biology of host-pathogen interactions. 
Gerard Schellenberg  
Ophir Shalem

We focus on translational target discovery for a range of early and late onset neurodegenerative diseases.

Li Shen The central theme of the Shen lab is focused on developing computational and informatics methods for integrative analysis of multimodal imaging data, high throughput omics data, cognitive and other biomarker data, electronic health record data, and rich biological knowledge (e.g., pathways and networks), with applications to various complex disorders.
Chris Stoeckert Integrative analysis of high throughput datasets to study cell development, differentiation, and function.
Kai Tan Our lab is interested in Systems Biology of gene regulation in normal and disease development.
Sarah Tishkoff Identification of funtionally important genomic variation in regulatory and coding regions
Golnaz Vahedi Utilization of non-coding genome in response to immune activation
Doris Wagner Molecular mechanisms controlling developmental transitions in response to environmental and endogenous cues.
Kai Wang The research in our laboratory focuses on the development of bioinformatics methods to improve our understanding of the genetic basis of human diseases, and the integration of electronic health records and genomic information to facilitate genomic medicine on scale.
Li-San Wang Function and structure of Non-coding RNAs; discovery of enhancers and target genes
Hao Wu The Wu lab is interested in understanding how epigenetic processes regulate gene expression to establish and maintain cellular identity.
Zhaolan (Joe) Zhou Epigenetic Control of Genome Function in Brain Development and Disease
Xi Ying Xi Ying The long-term goal of our research is to elucidate alternative isoform complexity in mammalian transcriptomes and proteomes