Perelman School of Medicine at the University of Pennsylvania

Geffen Laboratory of
Auditory Coding



Park, Y., Geffen, M.N. (2019) A Unifying Mechanistic Model of the Auditory Cortex with Inhibitory Subtypes. BioRXiv.

Aizenberg, M., Rolón-Martínez, S., Pham, Tuan., Rao, W., Haas, J., Geffen, M.N. (2019) A novel mechanism for amplification of sensory responses by the amygdala-TRN projections. BioRXiv.

Blackwell, J.M., Rao, W., De Biasi, M., Geffen, M.N. (2019) The role of feedback from the auditory cortex in shaping responses to sounds in inferior colliculus. BioRXiv.

Betzel, R.F., Wood, K.C., Angeloni, C.F., Geffen, M.N., Bassett, D.S. (2018) Stability of spontaneous, correlated activity in mouse auditory cortex. BioRXiv.

Gervain, J., Geffen, M.N. (2018) Efficient neural coding in auditory and speech perception. Trends in Neurosciences, published onlinepdf.

Angeloni, C., Geffen, M.N. (2018) Contextual modulation of sound processing in the auditory cortex. Current Opinion in Neurobiology, 49, 8–15. Article.pdf.

Briguglio, J.J., Aizenberg, M., Balasubramanian, V., Geffen, M.N. (2018) Cortical neural activity predicts sensory acuity under optogenetic manipulation. BioRXiv.  Journal of Neuroscience, 38 (8) 2094-2105. Article. 

Blackwell, J.M., Geffen, M.N. (2017) Progress and challenges for understanding the function of microcircuits in auditory processing. ​Nature Communications, 8: 2165. Article. pdf.

Natan, R.G., Rao, W., Geffen, M.N. (2017) Cortical interneurons ensure maintenance of frequency tuning following adaptation. Cell Reports, 21, 1-13. Articlepdf.

Wood, K.C., Blackwell, J.M., Geffen, M.N. (2017) Cortical inhibitory neurons control sensory processing. Current Opinion in Neurobiology, 46, 200-207. Article. pdf.

Natan, R.G., Isaac M. Carruthers, Laetitia Mwilambwe-Tshilobo, Geffen, M.N. (2017) Gain Control in the Auditory Cortex Evoked by Changing Temporal Correlation of Sounds. Cerebral Cortex, 27(3), 2385-2402. Pubmed. (FILE TOO LARGE) 

Gervain, J., Werker, J.F., Black, A., Geffen, M.N. (2016) The neural correlates of processing scale-invariant environmental sounds at birth. NeuroImage, 133:144-150. Pubmed. pdf.

Blackwell, J.M., Taillefumier, T.O., Natan, R.G., Carruthers, I.M., Magnasco, M.O., Geffen, M.N. (2016) Stable encoding of sounds over a broad range of statistical parameters in the auditory cortex. European Journal of Neuroscience, 43(6), 751–764. Pubmedpdf

​Aizenberg, M., Mwilambwe-Tshilobo, L., Briguglio, J.J., Natan, R.G., Geffen, M.N. (2015) Bi-directional regulation of innate and learned behaviors that rely on frequency discrimination by cortical inhibitory interneurons. PloS Biology, 13(12): e1002308. Pubmed. Article. pdf. (FILE TOO LARGE)

Natan, R.G., Briguglio, J.J., Mwilambwe-Tshilobo, L., Jones, S., Aizenberg, M., Goldberg, E.M., Geffen, M.N. (2015) Complementary control of sensory adaptation by two types of cortical interneurons. eLife, 10.7554/eLife.09868. PubmedArticle. pdf.

Carruthers, I.M., Laplagne, D.A., Jaegle, A., Briguglio, J.J. , Mwilambwe-Tshilobo, L., Natan, R.G., Geffen, M.N. (2015) Emergence of invariant representation of vocalizations in the auditory cortex. Journal of Neurophysiology, DOI 10.1152/jn.00095.2015. Pubmedpdf.

Mwilambwe-Tshilobo, L., Davis, A.J.O., Aizenberg, M., Geffen, M.N. (2015) Selective impairment in frequency discrimination in a mouse model of tinnitus.  PLoS One, DOI: 10.1371/journal.pone.0137749. Pubmedpdf.

Gervain, J., Werker, J.F., Geffen, M.N. (2014) Category-specific processing of scale-invariant sounds in infancy. (2014) PLoS One, 9(5): e96278. Pubmed. pdf.

Zaidi, Q., Victor, J.D., McDermott, J., Geffen, M.N., Bensmaia, S., Cleland, T.A. (2013) Perceptual Spaces: Mathematical structures to neural mechanisms. Journal of Neuroscience, 33(45), 17597-17602. Pubmed.  pdf.

Aizenberg, M., Geffen, M.N. (2013) Bidirectional effects of aversive learning on perceptual acuity are mediated by the sensory cortex. Nature Neuroscience, 16: 994-996. doi: 10.1038:nn.3443. Pubmed.  pdf.

Carruthers, I.M., Natan, R.G., Geffen, M.N. (2013) Encoding of ultra-sonic vocalizations in the rat auditory cortex. Journal of Neurophysiology, 109(7): 1912-1927. Pubmed. pdf.

Geffen, M.N., Gervain, J., Werker, J.F., Magnasco, M.O. (2011) Auditory perception of self-similarity in water sounds. Front. Integr. Neurosci. 5:15. Pubmedpdf.

---Before PENN---
Geffen, M.N., Broome, B.M., Laurent, G., Meister, M. (2009) Neural encoding of rapidly fluctuating odors. Neuron, 61(4), 570-586. Pubmedpdf.

Geffen, M.N., de Vries, S.E.J., and Meister, M. (2007) Retinal ganglion cells can rapidly change polarity from Off to On. PLoS Biology, 5(3), e65.  Pubmedpdf.

Andermann, M.L., Ritt, J., Neimark, M.A., Moore, C.I. (2004) Neural correlates of vibrissa resonance: band-pass and somatotopic representation of high-frequency stimuli. Neuron, 42, 451-463.  Pubmedpdf.

Neimark, M.A., Andermann, M.L., Hopfield, J.J. and Moore, C.I. (2003) Vibrissa resonance as a transduction mechanism for tactile encoding. J. Neuroscience 23(16), 6499-6509.  Pubmedpdf.