Hydrogen-Deuterium exchange Mass Spectrometry (HX-MS)

This methodology is useful for measuring protein backbone dynamics and structure in purified proteins and complexes. Solvent accessibility is reflected in the ability of hydrogens in the structure to exchange with deuterium in solvent, as measured by mass spectrometry.

  • LTQ-Orbitrap equipped with customized chromatography for HX on front end.

This instrument is located within the department at 1007 Stellar-Chance Laboratory

Contact:

Leland Mayne

mayne@pennmedicine.upenn.edu

Location:

1007 Stellar-Chance Laboratories

Prices for Usage:

See FY18-19 Rate Schedule

 

Download a billing form:

.docx or .pdf