Small-Angle X-ray Scattering (SAXS)

The angular-dependent elastic scattering of X-rays from macromolecules at very low angles can provide quantitative information about the shape, size, and physical properties of macromolecules in solution at low resolution. Further, with more recent innovations in ab initio shape reconstruction and atomic modelling, this information can provide a rigorous test for available atomic molecules. The technique requires samples of the highest purity and monodispersity, as validated by other complementary measures. 

  • Rigaku PSAXS small-angle x-ray scattering system equipped with Osmic mirror optics, a 3-pinhole enclosed pre-flight path, an evacuated sample chamber with customized sample holder, adjustable sample-to-detector distances, and gas-filled multi-wire detector served by the aforementioned rotating anode generator. The accessible q (where q=4πsinθ/λ) is 0.0055 < q < 0.25 Å-1, sufficient for the characterization of particles with length scales upwards of 500 Å.  A dedicated computer for data collection and analysis using the Rigaku SAXSGUI software package operates the instrument.
Small angle x-ray scattering system

PSAXS SMALL-ANGLE X-RAY SCATTERING SYSTEM

This instrument is located in the Department X-ray Crystallography Facility at G11 Blockley Hall

Contact:

Kushol Gupta

kgupta@pennmedicine.upenn.edu

Location:

G11 Blockley Hall

Phone:

215-573-9968

Prices for Usage:

See FY18-19 Rate Schedule

 

Download a billing form:

.docx or .pdf