Perelman School of Medicine at the University of Pennsylvania
The Beers Laboratory
Pulmonary, Allergy, and Critical Care Division of the University of Pennsylvania School of Medicine

University of Pennsylvania / School of Medicine / Beers Lab

Elena N. Atochina-Vasserman, M.D., Ph.D.

eavasserman

 

Senior Research Investigator

Lung Host Defense and Inflammation Core

University of Pennsylvania School of Medicine

Pulmonary, Allergy & Critical Care Division

Vernon and Shirley Hill Pavilion
Room H410C
380 S. University Ave.
Philadelphia, PA 19104-4539

Telephone: (215) 260-0569

Fax: (215) 893-4752

Email: atochina@mail.med.upenn.edu

Bio

M.D: Tomsk Medical School, Tomsk, Russia

Ph.D: Institute of Experimental Cardiology, Cardiology Research Center, Moscow, Russia.

Postdoctoral Fellowship: Institute for Environmental Medicine (IFEM), University of Pennsylvania, Philadelphia PA.

Research Fellowship: Pulmonary and Critical Care Division, University of Pennsylvania School of Medicine, Philadelphia PA.

Current: Senior Research Investigator, Pulmonary, Allergy, and Critical Care Division (PACCD) of the Department of Medicine at the University of Pennsylvania.

Research

The goal of my research is to better understand the molecular mechanisms involved in controlling Nitric Oxide (NO) signaling in the pathogenesis of both adult and neonatal pulmonary disease including ARDS, surfactant protein deficiencies, asthma and Hermansky Pudlak Syndrome. I am particularly interested in the function of NO in post-translational modification of the pulmonary surfactant, in particular, the lung collectins (SP-A and SP-D) and their functional consequences. Over the past decade our laboratory has investigated the role of SP-D in the pathophysiology of acute lung injury, bleomycin fibrosis, asthma, and Pneumocystis carinii lung infection. Our observations support the novel concept that SP-D plays a critical role in regulating innate immune responses within the lung. These findings are important because they may provide unique, novel therapeutical opportunities to control and manipulate the innate immune function in the lung.  

Recent Publications

 

 

Navigation