Andrew Matamoros, PhD
Department of Pathology and Laboratory Medicine,
University of Pennsylavnia
2008 B.A. Interdepartmental Biology and Psychology – University of Delaware, Newark, DE
2012 M.S. Molecular and Cellular Neuroscience – Delaware State University, Dover, DE
2018 Ph.D. Molecular and Cellular Biology and Genetics – Drexel University College of Medicine, Philadelphia, PA
2018-Present PennPORT fellow, Department of Pathology and Laboratory Medicine — Children’s Hospital of Philadelphia, Philadelphia, PA
Research Mentor: Dr. Yuanquan Song, Ph.D.
Research Topic: I am using a drosophila in vivo injury model to study nerve regeneration using a two-photon and confocal microscope. I am currently exploring how a microtubule associated protein, tubulin polymerization-promoting protein, may be upregulated following injury to promote regeneration of an injured neuron’s axon.
Teaching Interests: Introductory Biology, Cell Biology, Neuroscience, Development of the Nervous System, Axon Guidance, Nerve Injury and Neurodegeneration
Matamoros AJ, Tom VJ, Wu D, Rao Y, Sharp DJ, Baas PW. Knockdown of fidgetin improves regeneration of injured axons by a microtubule-based mechanism. (Submitted - In Review)
Austin TO, Matamoros AJ, Friedman JM, Friedman AJ, Nacharaju P, Yu W, Sharp DJ, Baas PW. Nanoparticle delivery of fidgetin siRNA as a microtubule-based therapy to augment nerve regeneration. Scientific Reports. 2017 Aug;7(1):9675.
Baas PW, Rao AN, Matamoros AJ, Leo L. Stability properties of neuronal microtubules. Cytoskeleton (Hoboken). 2016 Sep;73(9):442-60.
Matamoros AJ, Baas PW. Microtubules in health and degenerative disease of the nervous system. Brain Res Bull. 2016 Sep;126(Pt 3):217-225.
Baas PW, Matamoros AJ. Inhibition of kinesin-5 improves regeneration of injured axons by a novel microtubule-based mechanism. Neural Regen Res. 2015 Jun;10(6):845-9.