PennPORT
Helen Schmidt, Ph.D.
Department of Genetics,
University of Pennsylvania
Education:
2013 B.S. Biochemistry – University of Delaware, Newark, DE
2021 Ph.D. Human Genetics – Johns Hopkins University, Baltimore, MD
2021– Present Postdoctoral Researcher, Department of Genetics– University of Pennsylvania School of Medicine, Philadelphia, PA
Research Mentor: Meera Sundaram, Ph.D.
Research Topic: Using C. elegans model to investigate apical extracellular matrix assembly during epithelial tube formation on a single cell level
Teaching Interests: Using C. elegans model to investigate apical extracellular matrix assembly during epithelial tube formation on a single cell level
Publications:Young, A.F., Schmidt, H.F., Sundaram, M.V., 2022. Molecular lesions in alleles of the Caenorhabditis elegans lin-11 gene. MicroPubl Biol 2022.
Schmidt, H., Putnam, A., Rasoloson, D., Seydoux, G., 2021. Protein-based condensation mechanisms drive the assembly of RNA-rich P granules. eLife 10, e63698.
Smith, J., Calidas, D., Schmidt, H., Lu, T., Rasoloson, D., Seydoux, G., 2016. Spatial patterning of P granules by RNA-induced phase separation of the intrinsically-disordered protein MEG-3. Elife 5, e21337.
Paix, A., Schmidt, H., Seydoux, G., 2016. Cas9-assisted recombineering in C. elegans: genome editing using in vivo assembly of linear DNAs. Nucleic Acids Res. 44, e128.
Wang, J.T., Smith, J., Chen, B.-C., Schmidt, H., Rasoloson, D., Paix, A., Lambrus, B.G., Calidas, D., Betzig, E., Seydoux, G., 2014. Regulation of RNA granule dynamics by phosphorylation of serine-rich, intrinsically disordered proteins in C. elegans. Elife 3, e04591
Paix, A., Wang, Y., Smith, H.E., Lee, C.-Y.S., Calidas, D., Lu, T., Smith, J., Schmidt, H., Krause, M.W., Seydoux, G., 2014. Scalable and versatile genome editing using linear DNAs with microhomology to Cas9 Sites in Caenorhabditis elegans. Genetics 198, 1347–1356.
Schmidt, H.F., Sakowski, E.G., Williamson, S.J., Polson, S.W., Wommack, K.E., 2014. Shotgun metagenomics indicates novel family A DNA polymerases predominate within marine virioplankton. ISME J 8, 103–114.
E-mail: schmidth@pennmedicine.upenn.edu
© The Trustees of the University of Pennsylvania | Site best viewed in a supported browser. | Report Accessibility Issues and Get Help | Privacy Policy | Site Design: PMACS Web Team.