Research Description

My research interests are focused on the regulation of metabolism by hormones and nutrients, with a particular emphasis on the master regulators of organismal metabolism, insulin and glucose. Alterations in insulin and glucose signaling underlie metabolic disease and lead to the development of deadly vascular and neuronal complications. Through the use of various techniques encompassing molecular biology, biochemistry, metabolomics, genome-wide transcriptional techniques and whole-animal physiology, the long-term goals of my research program are to decipher the underlying mechanisms driving metabolic deregulation during disease and identify new therapies that improve metabolic control.

Diversity & Inclusion Initiatives

• Dr. Titchenell is particularly involved and committed to training the next generation of biomedical scientists. He is an active member of graduate education at Penn and serve on numerous committees including admission, thesis and examination committees. Additionally, Dr. Titchenell is passionate about supporting underrepresented minorities (URM) in biomedical science and is actively engaged in mentoring students and postdoctoral fellows from underrepresented backgrounds in his laboratory. Providing high-quality mentorship and training to students/fellows is an integral part of Dr. Titchenell’s academic mission