For more news highlights about basic science research at PennMedicine, see the PennMedicine Benchmarks e-newsletter.
- Penn Study Describes First Steps in Basic Biological Process that Could be Harnessed to Make Therapeutic Cells
16 Apr 2015
Understanding the molecular signals that guide early cells in the embryo to develop into different types of organs provides insight into how tissues regenerate and repair themselves. By knowing the principles that underlie the intricate steps in this transformation, researchers will be able to make new cells at will for transplantation and tissue repair in such situations as liver or heart disease.
- Limber Lungs: One Type of Airway Cell Can Regenerate Another Lung Cell Type
13 Apr 2015
A new collaborative study describes a way that lung tissue can regenerate after injury. The team found that lung tissue has more dexterity in repairing tissue than once thought.
- Research Team from Penn Receives Vaccine Industry Excellence Award
10 Apr 2015
The laboratory of David Weiner, PhD, a professor of Pathology and Laboratory Medicine at the Perelman School of Medicine at the University of Pennsylvania, received the 2015 Vaccine Industry Excellence Award for Best Academic Research Team, at the World Vaccine Congress in Washington, DC this week.
- Penn Medicine Hospitals Receive Accreditation, Top Honor from the American College of Surgeons Commission on Cancer
9 Apr 2015
The American College of Surgeons Commission on Cancer (CoC) has awarded three-year accreditation to three Penn Medicine hospitals in recognition of their commitment to the highest level of quality cancer care.
- Penn Medicine, Abramson Cancer Center Team Continues Progress in Investigational Gene Therapy for Blood Cancers
7 Apr 2015
The University of Pennsylvania research team behind pioneering studies of an investigational personalized cellular therapy for blood cancers has announced that the United States Patent and Trademark Office has issued several new patents on technologies related to this therapy, known as CTL019.
- Penn Study Shows Risk of Breast and Ovarian Cancer May Differ By Type of BRCA1, BRCA2 Mutation
7 Apr 2015
In a study involving more than 31,000 women with cancer-causing mutations in the BRCA1 or BRCA2 genes, researchers at the Basser Center for BRCA, the Abramson Cancer Center, and the Perelman School of Medicine at the University of Pennsylvania, identified mutations that are associated with significantly different risks of breast and ovarian cancers.
- Abramson Cancer Center Patients Walk Hospital Halls to Thank Marrow Donors, Support Future Patients
3 Apr 2015
Patients recovering from a bone marrow transplant and/or searching for a bone marrow donor can’t participate with the masses in an upcoming walk/run in Philadelphia celebrating marrow donation, but that won’t stop them from lacing up their shoes.
- Penn Medicine Researchers "Smell" New Receptors that Could Underlie the Many Actions of the Anesthetic Drug Ketamine
1 Apr 2015
Penn Medicine researchers are continuing their work in trying to understand the mechanisms through which anesthetics work to elicit the response that puts millions of Americans to sleep for surgeries each day. Their most recent study looked at ketamine, an anesthetic discovered in the 1960s and more recently prescribed as an anti-depressant at low doses.
- Blinking Cells: Penn Neuroscientist-Led Team is Finalist in NIH "Follow that Cell" Challenge to Fund Single Cell Biology
1 Apr 2015
James Eberwine, PhD, the Elmer Holmes Bobst Professor of Systems Pharmacology and Experimental Therapeutics, at the Perelman School of Medicine at the University of Pennsylvania, was named one of 16 finalists in the first phase of the Follow that Cell Challenge funded by the National Institutes of Health (NIH).
- HIV Patients Experience Better Kidney Transplant Outcomes than Hepatitis C Patients, According to Penn Study
31 Mar 2015
HIV (human immunodeficiency virus)-positive kidney transplant patients experienced superior outcomes when compared to kidney transplant patients with Hepatitis C and those infected with both HIV and Hepatitis C, according to a study led by researchers at the Perelman School of Medicine at the University of Pennsylvania and published online in Kidney International.
- Odds of Reversing ICU Patients' Prior Preferences to Forgo Life-Sustaining Therapies Vary Widely Across the U.S., according to Penn Study
30 Mar 2015
Intensive care units across the United States vary widely in how they manage the care of patients who have set preexisting limits on life-sustaining therapies, such as authorizing do-not-resuscitate (DNR) orders and prohibiting interventions such as feeding tubes or dialysis, according to new research from the Perelman School of Medicine at the University of Pennsylvania.
- Ken Burns Cancer Documentary to Feature Story of First Pediatric Patient to Receive Penn's Modified T Cell Therapy for Leukemia
30 Mar 2015
The story of the first pediatric patient to receive an experimental cellular therapy developed by researchers at the University of Pennsylvania will be featured in this week’s PBS documentary, “Cancer: The Emperor of All Maladies.”
- Malnourished Patients are More Likely to Suffer Postoperative Complications than Morbidly Obese Patients Following Knee, Hip Replacement, Penn Study Finds
27 Mar 2015
Malnourished patients are more likely to have complications following total knee or hip replacement surgeries than morbidly obese patients,according to new research from researchers at the Perelman School of Medicine at the University of Pennsylvania.
- Most NFL Players with Injuries to the Midfoot Return to Game Action, Penn Medicine Study Finds
27 Mar 2015
Nearly 93 percent of National Football League (NFL) athletes who sustained traumatic injuries to the midfoot returned to competition less than 15 months after injury and with no statistically significant decrease in performance, according to new research from the Perelman School of Medicine at the University of Pennsylvania.
- Roseroot Herb Shows Promise as Potential Depression Treatment Option, Penn Team Finds
26 Mar 2015
Rhodiola rosea (R. rosea), or roseroot, may be a beneficial treatment option for major depressive disorder (MDD), according to results of a study in the journal Phytomedicine led by Jun J. Mao, MD, MSCE, associate professor of Family Medicine, Community Health and Epidemiology and colleagues at the Perelman School of Medicine of University of Pennsylvania.
- Penn Medicine Experts Unveil Two New Ways to Identify Joint Replacement Patients at Risk for Post-Operative Complications
25 Mar 2015
Orthopedic surgeons from the Perelman School of Medicine at the University of Pennsylvania have developed two new prediction tools aimed at identifying total hip and knee replacement patients who are at-risk of developing serious complications after surgery.
- Penn Scientist Given Prestigious Award for Young Orthopaedic Researchers
25 Mar 2015
Robert L. Mauck, PhD, an associate professor of Orthopaedic Surgery at the Perelman School of Medicine at the University of Pennsylvania, is one of four scientists given awards by the Kappa Delta Sorority and the Orthopaedic Research and Education Foundation at the 2015 Annual Meeting of the American Academy of Orthopaedic Surgeons in Las Vegas.
- Penn Medicine Study: In Debated Surgical Procedure, Technique Trumps Technology
25 Mar 2015
A team of orthopedic surgeons from the Perelman School of Medicine at the University of Pennsylvania has found that modern technology for healing distal femur fractures is as safe and effective as its more established alternative, without a potential shortfall of the older approach.
- Media Toolkit: Penn Medicine at the American Academy of Orthopaedic Surgeons 2015 Annual Meeting
25 Mar 2015
Experts from the Perelman School of Medicine at the University of Pennsylvania will be moderating panels, serving as discussants and presenting research findings on the latest advances in orthopaedic surgery, research and education at the 2015 American Academy of Orthopaedic Surgerons Annual Meeting in Las Vegas, March 24-28, 2015.
- Penn Medicine Experts Offer Suggestions for Nudging Children toward Healthier Food Choices
23 Mar 2015
Strategies aimed at reducing childhood obesity should acknowledge individuals’ rational taste preferences and apply insights from behavioral economics to design choice architecture that increases their likelihood of success, say two physician-scientists from the Perelman School of Medicine at the University of Pennsylvania and the Center for Health Incentives and Behavioral Economics in an editorial published in JAMA Pediatrics.
- Genomewide Screen of Learning in Zebrafish Identifies Enzyme Important in Neural Circuit
23 Mar 2015
Researchers at the Perelman School of Medicine at the University of Pennsylvania describe the first set of genes important in learning in a zebrafish model in the journal Neuron this week. “Using an in-depth analysis of one of these genes, we have already revealed an important relevant signaling pathway,” says senior author Michael Granato, PhD, a professor of Cell and Developmental Biology.
- Penn Medicine Researchers Pinpoint Potential New Drug Target for Protection against Certain Neurodegenerative Diseases
20 Mar 2015
Penn Medicine researchers have discovered that hypermethylation - the epigenetic ability to turn down or turn off a bad gene implicated in 10 to 30 percent of patients with Amyotrophic Lateral Sclerosis (ALS) and Frontotemporal Degeneration (FTD) - serves as a protective barrier inhibiting the development of these diseases.
- Penn Medicine Study Finds Being Near Greened Vacant Lots Lowers Heart Rates
19 Mar 2015
Greening vacant lots may be associated with biologic reductions in stress, according to a new study from the Perelman School of Medicine at the University of Pennsylvania.
- Doctors of Tomorrow to Learn their Future at Emotion-Filled Match Day Ceremony at the Perelman School of Medicine
19 Mar 2015
Exhilaration. Stress. Drama. It’s all part of the annual Match Day experience for America’s graduating medical students. On Friday, March 20 at 12:00 pm, 159 medical students from the Perelman School of Medicine at the University of Pennsylvania, will find out, one by one, where they are headed for their residency training for the next three or more years.