The Robert A. Groff Endowed Professor and Vice Chairman for Research and Education in Neurosurgery
Douglas H. Smith, MD, is the Robert A. Groff Endowed Professor Neurosurgery and Director of the Center for Brain Injury and Repair at the University of Pennsylvania. In addition, Prof. Smith is the Scientific Director of the Big 10/ Ivy league Colaboration on Concussion and he also serves as a member on the Scientific Advisory Boards of the US National Football League (NFL), the National Collegiate Athletic Association (NCAA)-DoD consortium on concussion and the International Concussion Society. In addition, the U.S. State Department asked him to lead an investigation into neurological deficits induced in members of the embassy in Cuba, which led to a newly discovered disorder, “Havana Syndrome.” Prof. Smith’s group has established that damage to brain networks and specifically, diffuse axonal injury (DAI), represents key pathological processes underlying concussion symptoms and that the extent of acute axonal pathology is predictive of cognitive outcome. In addition, his group has discovered mechanisms of concussion and more severe TBI that lead to progressive neurodegeneration, including chronic traumatic encephalopathy. These collective efforts are represented in over 250 published scientific reports earning an h-index of over 85. His awards include the Dorothy Russell medal, the highest honor conveyed by the British Neuropathological Society and the William Osler Patient Oriented Research Award from the University of Pennsylvania.
Senior Research Investigator
Jean-Pierre received his PhD in Biomedical Engineering from Rutgers University, his MS in Biomedical Engineering from Drexel University and his BSc in Aeronautical Engineering from the University of Witwatersrand in South Africa. His research interests involve investigating the increased risk of dementia following traumatic brain injury events.
Post-Doctoral Researcher, Faculty Instructor
MD, Virginia Commonwealth University School of Medicine
Residency, Neurological Surgery, Yale-New Haven Hospital
Fellowship, Pediatric Neurosurgery, Children's Hospital of Philadelphia
Fellowship, Pediatric Spinal Deformity, Columbia University College of Physicians & Surgeons
BM, Capital Medical University, China
PhD, Department of Pathology and Anatomical Sciences, University of Missouri
BASc in Biology, Technion - Israel Institute of Technology, Israel
M.A.Sc in Medical Microbiology and Bacteriology, Bar-Ilan University, Israel
PhD in Pharmacology, Bar-Ilan University, Israel
Ishak received his PhD in Mechanical Engineering from The University of Texas at Arlington and BSc in Mechanical Engineering from Bangladesh University of Engineering and Technology. His research interests consist of experimental and computational modeling of axonal cytoskeletal components and associated biomolecules in traumatic brain injury (TBI).
Jingwen received her Master and PhD degree in Chemical Engineering at University of Missouri-Columbia. Her research background is biomaterial science and engineering.
Research interest: investigating changes in calcium synchronicity after traumatic axonal injury.
Hongmei received her medical degree from Bethune Medical School in China.
Research Interest: Network changes following in vitro axonal injury.
BA in Biology, Ursinus College
Research Interest: Determining injury thresholds following in vitro axonal injury
BA in Biology, Goucher College
Research Interest: Providing immunohistochemistry support for small and large animal tissue samples.
BS in Neuroscience, High Point University
BA in Philosophy, High Point University
University of Pennsylvania, C’22
Candidate for BA in Neuroscience
Minor Studies: Health Care Management, Chemistry, and Music