Publications

Feb 2023

• Post-Translational Chemical Modifications of Amyloid-β Peptides by 4-Hydroxy-2-Nonenal. Kikuchi H, Takahashi M, Komatsu H, Axelsen PH. J Alzheimers Dis. 2023 Feb 7. doi: 10.3233/JAD-220940. Online ahead of print. PMID: 36776059
• Alteration in Cerebral Metabolism in a Rodent Model of Acute Sub-lethal Cyanide Poisoning. Alomaja O, Shofer FS, Greenwood JC, Piel S, Clayman C, Mesaros C, Kao SH, Shin SS, Ehinger JK, Kilbaugh TJ, Jang DH. J Med Toxicol. 2023 Feb 9. doi: 10.1007/s13181-022-00928-w. Online ahead of print. PMID: 36757579
• Gene-environment interactions increase the risk of paediatric-onset multiple sclerosis associated with household chemical exposures. Nasr Z, Schoeps VA, Ziaei A, Virupakshaiah A, Adams C, Casper TC, Waltz M, Rose J, Rodriguez M, Tillema JM, Chitnis T, Graves JS, Benson L, Rensel M, Krupp L, Waldman AT, Weinstock-Guttman B, Lotze T, Greenberg B, Aaen G, Mar S, Schreiner T, Hart J, Simpson-Yap S, Mesaros C, Barcellos LF, Waubant E. J Neurol Neurosurg Psychiatry. 2023 Feb 1:jnnp-2022-330713. doi: 10.1136/jnnp-2022-330713. Online ahead of print. PMID: 36725329
• Neutrophil-activating therapy for the treatment of cancer. Linde IL, Prestwood TR, Qiu J, Pilarowski G, Linde MH, Zhang X, Shen L, Reticker-Flynn NE, Chiu DK, Sheu LY, Van Deursen S, Tolentino LL, Song WC, Engleman EG. Cancer Cell. 2023 Feb 13;41(2):356-372.e10. doi: 10.1016/j.ccell.2023.01.002. Epub 2023 Jan 26. PMID: 36706760

Jan 2023

• PAQR8 promotes breast cancer recurrence and confers resistance to multiple therapies. Chen S, Paul MR, Sterner CJ, Belka GK, Wang D, Xu P, Sreekumar A, Pan TC, Pant DK, Makhlin I, DeMichele A, Mesaros C, Chodosh LA. Breast Cancer Res. 2023 Jan 3;25(1):1. doi: 10.1186/s13058-022-01559-3. PMID: 36597146 
• Correction to: Preliminary Research: Application of Non-Invasive Measure of Cytochrome c Oxidase Redox States and Mitochondrial Function in a Porcine Model of Carbon Monoxide Poisoning. Lewis A, Forti RM, Alomaja O, Mesaros C, Piel S, Greenwood JC, Talebi FM, Mavroudis CD, Kelly M, Kao SH, Shofer FS, Ehinger JK, Kilbaugh TJ, Baker WB, Jang DH. J Med Toxicol. 2023 Jan;19(1):53. doi: 10.1007/s13181-022-00913-3. PMID: 36508082 
• Modulation of TRPV2 by endogenous and exogenous ligands: A computational study. Feng S, Pumroy RA, Protopopova AD, Moiseenkova-Bell VY, Im W. Protein Sci. 2023 Jan;32(1):e4490. doi: 10.1002/pro.4490. PMID: 36327382
• Germline Mutations in Steroid Metabolizing Enzymes: A Focus on Steroid Transforming Aldo-Keto Reductases. Detlefsen AJ, Paulukinas RD, Penning TM. Int J Mol Sci. 2023 Jan 18;24(3):1873. doi: 10.3390/ijms24031873. PMID: 36768194 
• Role of Human Aldo-Keto Reductases and Nuclear Factor Erythroid 2-Related Factor 2 in the Metabolic Activation of 1-Nitropyrene via Nitroreduction in Human Lung Cells. Su AL, Penning TM. Chem Res Toxicol. 2023 Jan 24. doi: 10.1021/acs.chemrestox.2c00337. Online ahead of print. PMID: 36693016
• Chimeric Antigen Receptor T-Cell Therapy: Current Perspective on T Cell-Intrinsic, T Cell-Extrinsic, and Therapeutic Limitations. Brookens SK, Posey AD Jr. Cancer J. 2023 Jan-Feb 01;29(1):28-33. doi: 10.1097/PPO.0000000000000636. PMID: 36693155 
• Mendelian Randomization Analysis Reveals a Complex Genetic Interplay among Atopic Dermatitis, Asthma, and Gastroesophageal Reflux Disease. Ahn K, Penn RB, Rattan S, Panettieri RA Jr, Voight BF, An SS. Am J Respir Crit Care Med. 2023 Jan 15;207(2):130-137. doi: 10.1164/rccm.202205-0951OC. PMID: 36214830
• Cancer cells resistant to immune checkpoint blockade acquire interferon-associated epigenetic memory to sustain T cell dysfunction. Qiu J, Xu B, Ye D, Ren D, Wang S, Benci JL, Xu Y, Ishwaran H, Beltra JC, Wherry EJ, Shi J, Minn AJ. Nat Cancer. 2023 Jan;4(1):43-61. doi: 10.1038/s43018-022-00490-y. Epub 2023 Jan 16. PMID: 36646856
• An extended SARS-CoV-2 mRNA vaccine prime-boost interval enhances B cell immunity with limited impact on T cells. Nicolas A, Sannier G, Dubé M, Nayrac M, Tauzin A, Painter MM, Goel RR, Laporte M, Gendron-Lepage G, Medjahed H, Williams JC, Brassard N, Niessl J, Gokool L, Morrisseau C, Arlotto P, Tremblay C, Martel-Laferrière V, Finzi A, Greenplate AR, Wherry EJ, Kaufmann DE. iScience. 2023 Jan 20;26(1):105904. doi: 10.1016/j.isci.2022.105904. Epub 2022 Dec 29. PMID: 36594081 

December 2022

• A novel Oprm1-Cre mouse maintains endogenous expression, function and enables detailed molecular characterization of μ-opioid receptor cells. Mengaziol J, Dunn AD, Salimando G, Wooldridge L, Crues-Muncunill J, Eacret D, Chen C, Bland K, Liu-Chen LY, Ehrlich ME, Corder G, Blendy JA. PLoS One. 2022 Dec 19;17(12):e0270317. doi: 10.1371/journal.pone.0270317. eCollection 2022. PMID: 36534642
• Cell-type specific profiling of histone post-translational modifications in the adult mouse striatum. Carpenter MD, Fischer DK, Zhang S, Bond AM, Czarnecki KS, Woolf MT, Song H, Heller EA. Nat Commun. 2022 Dec 13;13(1):7720. doi: 10.1038/s41467-022-35384-1. PMID: 36513652
• Convergent actions of stress and stimulants via epigenetic regulation of neural circuitry. Murphy MD, Heller EA. Trends Neurosci. 2022 Dec;45(12):955-967. doi: 10.1016/j.tins.2022.10.001. Epub 2022 Oct 22. PMID: 36280459
• Germline intergenic duplications at Xq26.1 underlie Bazex-Dupré-Christol basal cell carcinoma susceptibility syndrome. Liu Y, Banka S, Huang Y, Hardman-Smart J, Pye D, Torrelo A, Beaman GM, Kazanietz MG, Baker MJ, Ferrazzano C, Shi C, Orozco G, Eyre S, van Geel M, Bygum A, Fischer J, Miedzybrodzka Z, Abuzahra F, Rübben A, Cuvertino S, Ellingford JM, Smith MJ, Evans DG, Weppner-Parren LJMT, van Steensel MAM, Chaudhary IH, Mangham DC, Lear JT, Paus R, Frank J, Newman WG, Zhang X. Br J Dermatol. 2022 Dec;187(6):948-961. doi: 10.1111/bjd.21842. Epub 2022 Sep 12. PMID: 35986704
• Role of Human Aldo-Keto Reductases in the Nitroreduction of 1-Nitropyrene and 1,8-Dinitropyrene. Su AL, Mesaros CA, Krzeminski J, El-Bayoumy K, Penning TM. Chem Res Toxicol. 2022 Dec 19;35(12):2296-2309. doi: 10.1021/acs.chemrestox.2c00271. Epub 2022 Nov 18. PMID: 36399404
• An End Point-Specific Framework for Read-Across Analog Selection for Human Health Effects. Moustakas H, Date MS, Kumar M, Schultz TW, Liebler DC, Penning TM, Salvito DT, Api AM. Chem Res Toxicol. 2022 Dec 19;35(12):2324-2334. doi: 10.1021/acs.chemrestox.2c00286. Epub 2022 Dec 2. PMID: 36458907 
• Expression of inducible factors reprograms CAR-T cells for enhanced function and safety. Smole A, Benton A, Poussin MA, Eiva MA, Mezzanotte C, Camisa B, Greco B, Sharma P, Minutolo NG, Gray F, Bear AS, Baroja ML, Cummins C, Xu C, Sanvito F, Goldgewicht AL, Blanchard T, Rodriguez-Garcia A, Klichinsky M, Bonini C, June CH, Posey AD Jr, Linette GP, Carreno BM, Casucci M, Powell DJ Jr. Cancer Cell. 2022 Dec 12;40(12):1470-1487.e7. doi: 10.1016/j.ccell.2022.11.006. PMID: 36513049
• Non-steroidal anti-inflammatory drugs as a targeted therapy for bone marrow failure in Ghosal Hematodiaphyseal Dysplasia.

  Brown TJ, Barrett NA, Meng H, Ricciotti E, McDonnell CM, Dancis A, Qualtieri JN, FitzGerald GA, Cotter M, Babushok DV. Blood. 2022 Dec 27:blood.2022018667. doi: 10.1182/blood.2022018667. Online ahead of print. PMID: 36574346

• A decline of protective apolipoprotein J and complement factor H concomitant with increase in C5a 3 months after cardiac surgery-Evidence of long-term complement perturbations. Laudanski K, Liu D, Gullipalli D, Song WC, Okeke T, Szeto WY. Front Cardiovasc Med. 2022 Dec 20;9:983617. doi: 10.3389/fcvm.2022.983617. eCollection 2022. PMID: 36606279

• Mapping the T cell epitopes of the M-type transmembrane phospholipase A2 receptor in primary membranous nephropathy. Zhang XD, Lin CX, Cui Z, Gu QH, Yan BJ, Liu L, Song WC, Shi Y, Debiec H, Ronco P, Zhao MH. Kidney Int. 2022 Dec 20:S0085-2538(22)01039-0. doi: 10.1016/j.kint.2022.11.021. Online ahead of print. PMID: 36549363

• Genomics and phenomics of body mass index reveals a complex disease network. Huang J, Huffman JE, Huang Y, Do Valle Í, Assimes TL, Raghavan S, Voight BF, Liu C, Barabási AL, Huang RDL, Hui Q, Nguyen XT, Ho YL, Djousse L, Lynch JA, Vujkovic M, Tcheandjieu C, Tang H, Damrauer SM, Reaven PD, Miller D, Phillips LS, Ng MCY, Graff M, Haiman CA, Loos RJF, North KE, Yengo L, Smith GD, Saleheen D, Gaziano JM, Rader DJ, Tsao PS, Cho K, Chang KM, Wilson PWF; VA Million Veteran Program; Sun YV, O'Donnell CJ. Nat Commun. 2022 Dec 29;13(1):7973. doi: 10.1038/s41467-022-35553-2. PMID: 36581621 

• Validating a Proteomic Signature of Severe COVID-19. Cosgriff CV, Miano TA, Mathew D, Huang AC, Giannini HM, Kuri-Cervantes L, Pampena MB, Ittner CAG, Weisman AR, Agyekum RS, Dunn TG, Oniyide O, Turner AP, D'Andrea K, Adamski S, Greenplate AR, Anderson BJ, Harhay MO, Jones TK, Reilly JP, Mangalmurti NS, Shashaty MGS, Betts MR, Wherry EJ, Meyer NJ. Crit Care Explor. 2022 Dec 1;4(12):e0800. doi: 10.1097/CCE.0000000000000800. eCollection 2022 Dec. PMID: 36479446 

• Author Correction: Decade-long leukaemia remissions with persistence of CD4⁺CAR T cells. Melenhorst JJ, Chen GM, Wang M, Porter DL, Chen C, Collins MA, Gao P, Bandyopadhyay S, Sun H, Zhao Z, Lundh S, Pruteanu-Malinici I, Nobles CL, Maji S, Frey NV, Gill SI, Loren AW, Tian L, Kulikovskaya I, Gupta M, Ambrose DE, Davis MM, Fraietta JA, Brogdon JL, Young RM, Chew A, Levine BL, Siegel DL, Alanio C, Wherry EJ, Bushman FD, Lacey SF, Tan K, June CH. Nature. 2022 Dec;612(7941):E22. doi: 10.1038/s41586-022-05376-8. PMID: 36477542 

November 2022

• Extra-cardiac BCAA catabolism lowers blood pressure and protects from heart failure. Murashige D, Jung JW, Neinast MD, Levin MG, Chu Q, Lambert JP, Garbincius JF, Kim B, Hoshino A, Marti-Pamies I, McDaid KS, Shewale SV, Flam E, Yang S, Roberts E, Li L, Morley MP, Bedi KC Jr, Hyman MC, Frankel DS, Margulies KB, Assoian RK, Elrod JW, Jang C, Rabinowitz JD, Arany Z. Cell Metab. 2022 Nov 1;34(11):1749-1764.e7. doi: 10.1016/j.cmet.2022.09.008. Epub 2022 Oct 11. PMID: 36223763
• Ruxolitinib and exemestane for estrogen receptor positive, aromatase inhibitor resistant advanced breast cancer. Makhlin I, McAndrew NP, Wileyto EP, Clark AS, Holmes R, Bottalico LN, Mesaros C, Blair IA, Jeschke GR, Fox KR, Domchek SM, Matro JM, Bradbury AR, Feldman MD, Hexner EO, Bromberg JF, DeMichele A. NPJ Breast Cancer. 2022 Nov 11;8(1):122. doi: 10.1038/s41523-022-00487-x. PMID: 36369506 
• A common SNP in Chrna5 enhances morphine reward in female mice. Brynildsen JK, Yang K, Lemchi C, Dani JA, De Biasi M, Blendy JA. Neuropharmacology. 2022 Nov 1;218:109218. doi: 10.1016/j.neuropharm.2022.109218. Epub 2022 Aug 13. PMID: 35973602
• BLIMP1 and NR4A3 transcription factors reciprocally regulate antitumor CAR T cell stemness and exhaustion. Jung IY, Narayan V, McDonald S, Rech AJ, Bartoszek R, Hong G, Davis MM, Xu J, Boesteanu AC, Barber-Rotenberg JS, Plesa G, Lacey SF, Jadlowsky JK, Siegel DL, Hammill DM, Cho-Park PF, Berger SL, Haas NB, Fraietta JA. Sci Transl Med. 2022 Nov 9;14(670):eabn7336. doi: 10.1126/scitranslmed.abn7336. Epub 2022 Nov 9. PMID: 36350986
• Reconstitution of human adrenocortical specification and steroidogenesis using induced pluripotent stem cells. Sakata Y, Cheng K, Mayama M, Seita Y, Detlefsen AJ, Mesaros CA, Penning TM, Shishikura K, Yang W, Auchus RJ, Strauss JF 3rd, Sasaki K. Dev Cell. 2022 Nov 21;57(22):2566-2583.e8. doi: 10.1016/j.devcel.2022.10.010. PMID: 36413950 
• Genome-wide association and multi-trait analyses characterize the common genetic architecture of heart failure. Levin MG, Tsao NL, Singhal P, Liu C, Vy HMT, Paranjpe I, Backman JD, Bellomo TR, Bone WP, Biddinger KJ, Hui Q, Dikilitas O, Satterfield BA, Yang Y, Morley MP, Bradford Y, Burke M, Reza N, Charest B; Regeneron Genetics Center; Judy RL, Puckelwartz MJ, Hakonarson H, Khan A, Kottyan LC, Kullo I, Luo Y, McNally EM, Rasmussen-Torvik LJ, Day SM, Do R, Phillips LS, Ellinor PT, Nadkarni GN, Ritchie MD, Arany Z, Cappola TP, Margulies KB, Aragam KG, Haggerty CM, Joseph J, Sun YV, Voight BF, Damrauer SM. Nat Commun. 2022 Nov 14;13(1):6914. doi: 10.1038/s41467-022-34216-6. PMID: 36376295
• Tumor factors stimulate lysosomal degradation of tumor antigens and undermine their cross-presentation in lung cancer. Lu Z, Chen J, Yu P, Atherton MJ, Gui J, Tomar VS, Middleton JD, Sullivan NT, Singhal S, George SS, Woolfork AG, Weljie AM, Hai T, Eruslanov EB, Fuchs SY. Nat Commun. 2022 Nov 4;13(1):6623. doi: 10.1038/s41467-022-34428-w. PMID: 36333297
• Divergent clonal differentiation trajectories of T cell exhaustion. Daniel B, Yost KE, Hsiung S, Sandor K, Xia Y, Qi Y, Hiam-Galvez KJ, Black M, J Raposo C, Shi Q, Meier SL, Belk JA, Giles JR, Wherry EJ, Chang HY, Egawa T, Satpathy AT. Nat Immunol. 2022 Nov;23(11):1614-1627. doi: 10.1038/s41590-022-01337-5. Epub 2022 Oct 26. PMID: 36289450
• Shared and distinct biological circuits in effector, memory and exhausted CD8⁺ T cells revealed by temporal single-cell transcriptomics and epigenetics. Giles JR, Ngiow SF, Manne S, Baxter AE, Khan O, Wang P, Staupe R, Abdel-Hakeem MS, Huang H, Mathew D, Painter MM, Wu JE, Huang YJ, Goel RR, Yan PK, Karakousis GC, Xu X, Mitchell TC, Huang AC, Wherry EJ. Nat Immunol. 2022 Nov;23(11):1600-1613. doi: 10.1038/s41590-022-01338-4. Epub 2022 Oct 21. PMID: 36271148

October 2022

• Cell contractility and Focal Adhesion Kinase control circumferential arterial stiffness. Roberts E, Xu T, Assoian R. Vasc Biol. 2022 Oct 1;4(1):28-39. doi: 10.1530/VB-22-0013. Online ahead of print. PMID: 36222505 
• Characterization and Quantification of Oxidized High Mobility Group Box 1 Proteoforms Secreted from Hepatocytes by Toxic Levels of Acetaminophen. Pirnie R, Gillespie KP, Weng L, Mesaros C, Blair IA. Chem Res Toxicol. 2022 Oct 17;35(10):1893-1902. doi: 10.1021/acs.chemrestox.2c00161. Epub 2022 Aug 3. PMID: 35922039 
• Nonredundant Rac-GEF control of actin cytoskeleton reorganization. Kazanietz MG, Cooke M, Garcia-Mata R. Trends Cell Biol. 2022 Oct;32(10):815-818. doi: 10.1016/j.tcb.2022.06.003. Epub 2022 Jun 23. PMID: 35753960
• Estimating the effect size of a hidden causal factor between SNPs and a continuous trait: a mediation model approach. Ding Z, Ritchie MD, Voight BF, Hwang WT. BMC Bioinformatics. 2022 Oct 13;23(1):420. doi: 10.1186/s12859-022-04977-4. PMID: 36229773 
• PPT1 inhibition enhances the antitumor activity of anti-PD-1 antibody in melanoma. Sharma G, Ojha R, Noguera-Ortega E, Rebecca VW, Attanasio J, Liu S, Piao S, Lee JJ, Nicastri MC, Harper SL, Ronghe A, Jain V, Winkler JD, Speicher DW, Mastio J, Gimotty PA, Xu X, Wherry EJ, Gabrilovich DI, Amaravadi RK. JCI Insight. 2022 Oct 24;7(20):e165688. doi: 10.1172/jci.insight.165688. PMID: 36278493
• SARS-CoV-2 infections elicit higher levels of original antigenic sin antibodies compared with SARS-CoV-2 mRNA vaccinations. Anderson EM, Li SH, Awofolaju M, Eilola T, Goodwin E, Bolton MJ, Gouma S, Manzoni TB, Hicks P, Goel RR, Painter MM, Apostolidis SA, Mathew D, Dunbar D, Fiore D, Brock A, Weaver J, Millar JS, DerOhannessian S; UPenn COVID Processing Unit; Greenplate AR, Frank I, Rader DJ, Wherry EJ, Bates P, Hensley SE. Cell Rep. 2022 Oct 18;41(3):111496. doi: 10.1016/j.celrep.2022.111496. PMID: 36261003 
• A boost with SARS-CoV-2 BNT162b2 mRNA vaccine elicits strong humoral responses independently of the interval between the first two doses. Tauzin A, Gong SY, Chatterjee D, Ding S, Painter MM, Goel RR, Beaudoin-Bussières G, Marchitto L, Boutin M, Laumaea A, Okeny J, Gendron-Lepage G, Bourassa C, Medjahed H, Goyette G, Williams JC, Bo Y, Gokool L, Morrisseau C, Arlotto P, Bazin R, Fafard J, Tremblay C, Kaufmann DE, De Serres G, Richard J, Côté M, Duerr R, Martel-Laferrière V, Greenplate AR, Wherry EJ, Finzi A. Cell Rep. 2022 Oct 25;41(4):111554. doi: 10.1016/j.celrep.2022.111554. Epub 2022 Oct 5. PMID: 36244343 
• Correction for Merenstein et al., "Signatures of COVID-19 Severity and Immune Response in the Respiratory Tract Microbiome". Merenstein C, Liang G, Whiteside SA, Cobián-Güemes AG, Merlino MS, Taylor LJ, Glascock A, Bittinger K, Tanes C, Graham-Wooten J, Khatib LA, Fitzgerald AS, Reddy S, Baxter AE, Giles JR, Oldridge DA, Meyer NJ, Wherry EJ, McGinniss JE, Bushman FD, Collman RG. mBio. 2022 Oct 26;13(5):e0229322. doi: 10.1128/mbio.02293-22. Epub 2022 Aug 31. PMID: 36043873 

September 2022

• Cocaine regulation of Nr4a1 chromatin bivalency and mRNA in male and female mice. Fischer DK, Krick KS, Han C, Woolf MT, Heller EA. Sci Rep. 2022 Sep 21;12(1):15735. doi: 10.1038/s41598-022-19908-9. PMID: 36130958 
• Mechanical strain stimulates COPII-dependent secretory trafficking via Rac1. Phuyal S, Djaerff E, Le Roux AL, Baker MJ, Fankhauser D, Mahdizadeh SJ, Reiterer V, Parizadeh A, Felder E, Kahlhofer JC, Teis D, Kazanietz MG, Geley S, Eriksson L, Roca-Cusachs P, Farhan H. EMBO J. 2022 Sep 15;41(18):e110596. doi: 10.15252/embj.2022110596. Epub 2022 Aug 8. PMID: 35938214 
• What structures did, and did not, reveal about the function of the epithelial Ca²⁺channels TRPV5 and TRPV6. Rohacs T, Fluck EC, De Jesús-Pérez JJ, Moiseenkova-Bell VY. Cell Calcium. 2022 Sep;106:102620. doi: 10.1016/j.ceca.2022.102620. Epub 2022 Jul 3. PMID: 35834842 
• Topical nitroglycerin to detect reversible microcirculatory dysfunction in patients with circulatory shock after cardiovascular surgery: an observational study. Greenwood JC, Talebi FM, Jang DH, Spelde AE, Tonna JE, Gutsche JT, Horak J, Acker MA, Kilbaugh TJ, Shofer FS, Augoustides JGT, Bakker J, Brenner JS, Muzykantov VR, Abella BS. Sci Rep. 2022 Sep 10;12(1):15257. doi: 10.1038/s41598-022-19741-0. PMID: 36088474 
• Quantification of Plasma 8-Isoprostane by High-Performance Liquid Chromatography with Tandem Mass Spectrometry in a Case-Control Study of Lung Cancer. Ma L, Sun D, Xiu G, Lazarus P, Vachani A, Penning TM, Whitehead AS, Muscat JE. Int J Environ Res Public Health. 2022 Sep 30;19(19):12488. doi: 10.3390/ijerph191912488. PMID: 36231826 
• ColocQuiaL: a QTL-GWAS colocalization pipeline. Chen BY, Bone WP, Lorenz K, Levin M, Ritchie MD, Voight BF. Bioinformatics. 2022 Sep 15;38(18):4409-4411. doi: 10.1093/bioinformatics/btac512. PMID: 35894642 
• Building effective collaborations for the study of COVID-19 across the severity spectrum. Agyekum RS, Abramoff BA, Wherry EJ, Meyer NJ. Nat Immunol. 2022 Sep;23(9):1287-1290. doi: 10.1038/s41590-022-01283-2. PMID: 35999396 

August 2022

• Characterization and Quantification of Oxidized High Mobility Group Box 1 Proteoforms Secreted from Hepatocytes by Toxic Levels of Acetaminophen. Pirnie R, Gillespie KP, Weng L, Mesaros C, Blair IA. Chem Res Toxicol. 2022 Aug 3. doi: 10.1021/acs.chemrestox.2c00161. Online ahead of print. PMID: 35922039
• A common SNP in Chrna5 enhances morphine reward in female mice. Brynildsen JK, Yang K, Lemchi C, Dani JA, De Biasi M, Blendy JA. Neuropharmacology. 2022 Aug 13:109218. doi: 10.1016/j.neuropharm.2022.109218. Online ahead of print. PMID: 35973602
• Germline intergenic duplications at Xq26.1 underlie Bazex-Dupré-Christol basal cell carcinoma susceptibility syndrome. Liu Y, Banka S, Huang Y, Hardman-Smart J, Pye D, Torrelo A, Beaman GM, Kazanietz MG, Baker MJ, Ferrazzano C, Shi C, Orozco G, Eyre S, van Geel M, Bygum A, Fischer J, Miedzybrodzka Z, Abuzahra F, Rübben A, Cuvertino S, Ellingford JM, Smith MJ, Evans DG, Weppner-Parren LJMT, van Steensel MAM, Chaudhary IH, Mangham DC, Lear JT, Paus R, Frank J, Newman WG, Zhang X. Br J Dermatol. 2022 Aug 20. doi: 10.1111/bjd.21842. Online ahead of print. PMID: 35986704
• Mechanical strain stimulates COPII-dependent secretory trafficking via Rac1. Phuyal S, Djaerff E, Le Roux AL, Baker MJ, Fankhauser D, Mahdizadeh SJ, Reiterer V, Parizadeh A, Felder E, Kahlhofer JC, Teis D, Kazanietz MG, Geley S, Eriksson L, Roca-Cusachs P, Farhan H. EMBO J. 2022 Aug 8:e110596. doi: 10.15252/embj.2022110596. Online ahead of print. PMID: 35938214
• Automating Predictive Toxicology Using ComptoxAI. Romano JD, Hao Y, Moore JH, Penning TM. Chem Res Toxicol. 2022 Aug 15;35(8):1370-1382. doi: 10.1021/acs.chemrestox.2c00074. Epub 2022 Jul 12. PMID: 35819939
• Air pollution and lung cancer survival in Pennsylvania. McKeon TP, Anil Vachani, Penning TM, Hwang WT. Lung Cancer. 2022 Aug;170:65-73. doi: 10.1016/j.lungcan.2022.06.004. Epub 2022 Jun 10. PMID: 35716633
• Single-cell transcriptomics and cell-specific proteomics reveals molecular signatures of sleep. Jha PK, Valekunja UK, Ray S, Nollet M, Reddy AB. Commun Biol. 2022 Aug 19;5(1):846. doi: 10.1038/s42003-022-03800-3. PMID: 35986171 
• A disturbed balance between blood complement protective factors (FH, ApoE) and common pathway effectors (C5a, TCC) in acute COVID-19 and during convalesce. Laudanski K, Okeke T, Siddiq K, Hajj J, Restrepo M, Gullipalli D, Song WC. Sci Rep. 2022 Aug 11;12(1):13658. doi: 10.1038/s41598-022-17011-7. PMID: 35953544 PMCID: PMC9366819

July 2022

• Free Radical Chain Reactions and Polyunsaturated Fatty Acids in Brain Lipids. Ng SCW, Furman R, Axelsen PH, Shchepinov MS.
  ACS Omega. 2022 Jul 14;7(29):25337-25345. doi: 10.1021/acsomega.2c02285. eCollection 2022 Jul 26. PMID: 35910174 PMCID: PMC9330197
• The Kinetics and (Dys)kinetics of Cancer Chronotherapy. Field JM, Sehgal A. Cancer Res. 2022 Jul 5;82(13):2357-2360. doi: 10.1158/0008-5472.CAN-21-3799. PMID: 35709495 PMCID: PMC9256782
• Targeted In Vivo Loading of Red Blood Cells Markedly Prolongs Nanocarrier Circulation. Glassman PM, Villa CH, Marcos-Contreras OA, Hood ED, Walsh LR, Greineder CF, Myerson JW, Shuvaeva T, Puentes L, Brenner JS, Siegel DL, Muzykantov VR. Bioconjug Chem. 2022 Jul 20;33(7):1286-1294. doi: 10.1021/acs.bioconjchem.2c00196. Epub 2022 Jun 16. PMID: 35710322
• Skin fibroblast metabolomic profiling reveals that lipid dysfunction predicts the severity of Friedreich's ataxia. Wang D, Ho ES, Cotticelli MG, Xu P, Napierala JS, Hauser LA, Napierala M, Himes BE, Wilson RB, Lynch DR, Mesaros C. J Lipid Res. 2022 Jul 16;63(9):100255. doi: 10.1016/j.jlr.2022.100255. Online ahead of print. PMID: 35850241 
• Conversion of Classical and 11-Oxygenated Androgens by Insulin-Induced AKR1C3 in a Model of Human PCOS Adipocytes. Paulukinas RD, Mesaros CA, Penning TM. Endocrinology. 2022 Jul 1;163(7):bqac068. doi: 10.1210/endocr/bqac068. PMID: 35560164
• Preliminary Research: Application of Non-Invasive Measure of Cytochrome c Oxidase Redox States and Mitochondrial Function in a Porcine Model of Carbon Monoxide Poisoning. Lewis AT, Forti RM, Alomaja O, Mesaros C, Piel S, Greenwood JC, Talebi FM, Mavroudis CD, Kelly M, Kao SH, Shofer FS, Ehinger JK, Kilbaugh TJ, Baker WB, Jang DH. J Med Toxicol. 2022 Jul;18(3):214-222. doi: 10.1007/s13181-022-00892-5. Epub 2022 Apr 28. PMID: 35482181 PMCID: PMC9198167
• What structures did, and did not, reveal about the function of the epithelial Ca2+ channels TRPV5 and TRPV6. Rohacs T, Fluck EC, De Jesús-Pérez JJ, Moiseenkova-Bell VY. Cell Calcium. 2022 Jul 3;106:102620. doi: 10.1016/j.ceca.2022.102620. Online ahead of print. PMID: 35834842 
• Red Blood Cell Anchoring Enables Targeted Transduction and Re-Administration of AAV-Mediated Gene Therapy. Zhao Z, Kim J, Suja VC, Kapate N, Gao Y, Guo J, Muzykantov VR, Mitragotri S. Adv Sci (Weinh). 2022 Jul 3:e2201293. doi: 10.1002/advs.202201293. Online ahead of print. PMID: 35780495
• Peripheral blood leukocyte mitochondrial DNA content and risk of lung cancer. Kennedy GT, Mitra N, Penning TM, Whitehead AS, Vachani A. Transl Lung Cancer Res. 2022 Jul;11(7):1268-1278. doi: 10.21037/tlcr-21-979. PMID: 35958326 PMCID: PMC9359958
• Characterization of the major single nucleotide polymorphic variants of aldo-keto reductase 1C3 (type 5 17β-hydroxysteroid dehydrogenase). Detlefsen AJ, Wangtrakuldee P, Penning TM. J Steroid Biochem Mol Biol. 2022 Jul;221:106121. doi: 10.1016/j.jsbmb.2022.106121. Epub 2022 Apr 28. PMID: 35489629
• The surfaceome of multiple myeloma cells suggests potential immunotherapeutic strategies and protein markers of drug resistance. Ferguson ID, Patiño-Escobar B, Tuomivaara ST, Lin YT, Nix MA, Leung KK, Kasap C, Ramos E, Nieves Vasquez W, Talbot A, Hale M, Naik A, Kishishita A, Choudhry P, Lopez-Girona A, Miao W, Wong SW, Wolf JL, Martin TG 3rd, Shah N, Vandenberg S, Prakash S, Besse L, Driessen C, Posey AD Jr, Mullins RD, Eyquem J, Wells JA, Wiita AP. Nat Commun. 2022 Jul 15;13(1):4121. doi: 10.1038/s41467-022-31810-6. PMID: 35840578 
• ColocQuiaL: A QTL-GWAS colocalization pipeline. Chen BY, Bone WP, Lorenz K, Levin M, Ritchie MD, Voight BF. Bioinformatics. 2022 Jul 27:btac512. doi: 10.1093/bioinformatics/btac512. Online ahead of print. PMID: 35894642
• Epigenomic and transcriptomic analyses define core cell types, genes and targetable mechanisms for kidney disease. Liu H, Doke T, Guo D, Sheng X, Ma Z, Park J, Vy HMT, Nadkarni GN, Abedini A, Miao Z, Palmer M, Voight BF, Li H, Brown CD, Ritchie MD, Shu Y, Susztak K. Nat Genet. 2022 Jul;54(7):950-962. doi: 10.1038/s41588-022-01097-w. Epub 2022 Jun 16. PMID: 35710981

June 2022

• Ultrasensitive Single Extracellular Vesicle Detection Using High Throughput Droplet Digital Enzyme-Linked Immunosorbent Assay. Yang Z, Atiyas Y, Shen H, Siedlik MJ, Wu J, Beard K, Fonar G, Dolle JP, Smith DH, Eberwine JH, Meaney DF, Issadore DA. Nano Lett. 2022 Jun 8;22(11):4315-4324. doi: 10.1021/acs.nanolett.2c00274. Epub 2022 May 19. PMID: 35588529
• Nonredundant Rac-GEF control of actin cytoskeleton reorganization. Kazanietz MG, Cooke M, Garcia-Mata R. Trends Cell Biol. 2022 Jun 23:S0962-8924(22)00142-8. doi: 10.1016/j.tcb.2022.06.003. Online ahead of print. PMID: 35753960
• Quantification of ruffle area and dynamics in live or fixed lung adenocarcinoma cells. Kreider-Letterman G, Cooke M, Goicoechea SM, Kazanietz MG, Garcia-Mata R. STAR Protoc. 2022 Jun 4;3(2):101437. doi: 10.1016/j.xpro.2022.101437. eCollection 2022 Jun 17. PMID: 35677607 
• Astrocyte ethanol exposure reveals persistent and defined calcium response subtypes and associated gene signatures. Kim HB, Lu Y, Oh SC, Morris J, Miyashiro K, Kim J, Eberwine J, Sul JY. J Biol Chem. 2022 Jun 16;298(8):102147. doi: 10.1016/j.jbc.2022.102147. Online ahead of print. PMID: 35716779 PMCID: PMC9293641
• TSABL: Trait Specific Annotation Based Locus predictor. Lorenz K, Thom CS, Adurty S, Voight BF. BMC Genomics. 2022 Jun 15;23(1):444. doi: 10.1186/s12864-022-08654-x. PMID: 35705896 
• Characterization of the genome and silk-gland transcriptomes of Darwin's bark spider (Caerostris darwini). Babb PL, Gregorič M, Lahens NF, Nicholson DN, Hayashi CY, Higgins L, Kuntner M, Agnarsson I, Voight BF. PLoS One. 2022 Jun 6;17(6):e0268660. doi: 10.1371/journal.pone.0268660. eCollection 2022. PMID: 35666730 PMCID: PMC9170102
• A multiancestry genome-wide association study of unexplained chronic ALT elevation as a proxy for nonalcoholic fatty liver disease with histological and radiological validation. Vujkovic M, Ramdas S, Lorenz KM, Guo X, Darlay R, Cordell HJ, He J, Gindin Y, Chung C, Myers RP, Schneider CV, Park J, Lee KM, Serper M, Carr RM, Kaplan DE, Haas ME, MacLean MT, Witschey WR, Zhu X, Tcheandjieu C, Kember RL, Kranzler HR, Verma A, Giri A, Klarin DM, Sun YV, Huang J, Huffman JE, Townsend Creasy K, Hand NJ, Liu CT, Long MT, Yao J, Budoff M, Tan J, Li X, Lin HJ, Chen YI, Taylor KD, Chang RK, Krauss RM, Vilarinho S, Brancale J, Nielsen JB, Locke AE, Jones MB, Verweij N, Baras A, Reddy KR, Neuschwander-Tetri BA, Schwimmer JB, Sanyal AJ, Chalasani N, Ryan KA, Mitchell BD, Gill D, Wells AD, Manduchi E, Saiman Y, Mahmud N, Miller DR, Reaven PD, Phillips LS, Muralidhar S, DuVall SL, Lee JS, Assimes TL, Pyarajan S, Cho K, Edwards TL, Damrauer SM, Wilson PW, Gaziano JM, O'Donnell CJ, Khera AV, Grant SFA, Brown CD, Tsao PS, Saleheen D, Lotta LA, Bastarache L, Anstee QM, Daly AK, Meigs JB, Rotter JI, Lynch JA; Regeneron Genetics Center; Geisinger-Regeneron DiscovEHR Collaboration; EPoS Consortium; VA Million Veteran Program, Rader DJ, Voight BF, Chang KM. Nat Genet. 2022 Jun;54(6):761-771. doi: 10.1038/s41588-022-01078-z. Epub 2022 Jun 2. PMID: 35654975 
• A multi-population phenome-wide association study of genetically-predicted height in the Million Veteran Program. Raghavan S, Huang J, Tcheandjieu C, Huffman JE, Litkowski E, Liu C, Ho YA, Hunter-Zinck H, Zhao H, Marouli E, North KE; VA Million Veteran Program, Lange E, Lange LA, Voight BF, Gaziano JM, Pyarajan S, Hauser ER, Tsao PS, Wilson PWF, Chang KM, Cho K, O'Donnell CJ, Sun YV, Assimes TL. PLoS Genet. 2022 Jun 2;18(6):e1010193. doi: 10.1371/journal.pgen.1010193. eCollection 2022 Jun. PMID: 35653334 
• Multi-phenotype analyses of hemostatic traits with cardiovascular events reveal novel genetic associations. Temprano-Sagrera G, Sitlani CM, Bone WP, Martin-Bornez M, Voight BF, Morrison AC, Damrauer SM, de Vries PS, Smith NL, Sabater-Lleal M. J Thromb Haemost. 2022 Jun;20(6):1331-1349. doi: 10.1111/jth.15698. Epub 2022 Mar 29. PMID: 35285134 

May 2022

• Bcl-xL Enforces a Slow-Cycling State Necessary for Survival in the Nutrient-Deprived Microenvironment of Pancreatic Cancer.
  Sela Y, Li J, Maheswaran S, Norgard R, Yuan S, Hubbi M, Doepner M, Xu JP, Ho ES, Mesaros C, Sheehan C, Croley G, Muir A, Blair IA, Shalem O, Dang CV, Stanger BZ. Cancer Res. 2022 May 16;82(10):1890-1908. doi: 10.1158/0008-5472.CAN-22-0431. PMID: 35315913 PMCID: PMC9117449
• Targeting vascular inflammation through emerging methods and drug carriers. Nong J, Glassman PM, Muzykantov VR. Adv Drug Deliv Rev. 2022 May;184:114180. doi: 10.1016/j.addr.2022.114180. Epub 2022 Mar 7. PMID: 35271986 
• Identification of spatio-temporal clusters of lung cancer cases in Pennsylvania, USA: 2010-2017. Camiña N, McWilliams TL, McKeon TP, Penning TM, Hwang WT. BMC Cancer. 2022 May 17;22(1):555. doi: 10.1186/s12885-022-09652-8. PMID: 35581566 PMCID: PMC9112439
• Genetic and epigenetic regulation of the NRF2-KEAP1 pathway in human lung cancer. Camiña N, Penning TM. Br J Cancer. 2022 May;126(9):1244-1252. doi: 10.1038/s41416-021-01642-0. Epub 2021 Nov 29. PMID: 34845361 

April 2022

• Deuterated docosahexaenoic acid protects against oxidative stress and geographic atrophy-like retinal degeneration in a mouse model with iron overload. Liu Y, Bell BA, Song Y, Zhang K, Anderson B, Axelsen PH, Bohannan W, Agbaga MP, Park HG, James G, Brenna JT, Schmidt K, Dunaief JL, Shchepinov MS. Aging Cell. 2022 Apr;21(4):e13579. doi: 10.1111/acel.13579. Epub 2022 Mar 8. PMID: 35257475 PMCID: PMC9009113
• Simultaneous Quantification of Mitochondrial Mature Frataxin and Extra-Mitochondrial Frataxin Isoform E in Friedreich's Ataxia Blood. Wang Q, Laboureur L, Weng L, Eskenazi NM, Hauser LA, Mesaros C, Lynch DR, Blair IA. Front Neurosci. 2022 Apr 28;16:874768. doi: 10.3389/fnins.2022.874768. eCollection 2022. PMID: 35573317 PMCID: PMC9098139 
• Overarching roles of diacylglycerol signaling in cancer development and antitumor immunity. Cooke M, Kazanietz MG. Sci Signal. 2022 Apr 12;15(729):eabo0264. doi: 10.1126/scisignal.abo0264. Epub 2022 Apr 12. PMID: 35412850 
• Added to pre-existing inflammation, mRNA-lipid nanoparticles induce inflammation exacerbation (IE). Parhiz H, Brenner JS, Patel PN, Papp TE, Shahnawaz H, Li Q, Shi R, Zamora ME, Yadegari A, Marcos-Contreras OA, Natesan A, Pardi N, Shuvaev VV, Kiseleva R, Myerson JW, Uhler T, Riley RS, Han X, Mitchell MJ, Lam K, Heyes J, Weissman D, Muzykantov VR. J Control Release. 2022 Apr;344:50-61. doi: 10.1016/j.jconrel.2021.12.027. Epub 2021 Dec 23. PMID: 34953981 PMCID: PMC8695324
• Structural insights into TRPV2 activation by small molecules. Pumroy RA, Protopopova AD, Fricke TC, Lange IU, Haug FM, Nguyen PT, Gallo PN, Sousa BB, Bernardes GJL, Yarov-Yarovoy V, Leffler A, Moiseenkova-Bell VY. Nat Commun. 2022 Apr 28;13(1):2334. doi: 10.1038/s41467-022-30083-3. PMID: 35484159 
• Structural basis of TRPV5 regulation by physiological and pathophysiological modulators. Fluck EC, Yazici AT, Rohacs T, Moiseenkova-Bell VY. Cell Rep. 2022 Apr 26;39(4):110737. doi: 10.1016/j.celrep.2022.110737. PMID: 35476976 PMCID: PMC9088182
• AKR1D1 knockout mice develop a sex-dependent metabolic phenotype. Gathercole LL, Nikolaou N, Harris SE, Arvaniti A, Poolman TM, Hazlehurst JM, Kratschmar DV, Todorčević M, Moolla A, Dempster N, Pink RC, Saikali MF, Bentley L, Penning TM, Ohlsson C, Cummins CL, Poutanen M, Odermatt A, Cox RD, Tomlinson JW. J Endocrinol. 2022 Apr 13;253(3):97-113. doi: 10.1530/JOE-21-0280. PMID: 35318963 

March 2022

• DNA methylation in Friedreich ataxia silences expression of frataxin isoform E. Rodden LN, Gilliam KM, Lam C, Rojsajjakul T, Mesaros C, Dionisi C, Pook M, Pandolfo M, Lynch DR, Blair IA, Bidichandani SI. Sci Rep. 2022 Mar 23;12(1):5031. doi: 10.1038/s41598-022-09002-5. PMID: 35322126 PMCID: PMC8943190 
• Dual Affinity to RBCs and Target Cells (DART) Enhances Both Organ- and Cell Type-Targeting of Intravascular Nanocarriers. Ferguson LT, Hood ED, Shuvaeva T, Shuvaev VV, Basil MC, Wang Z, Nong J, Ma X, Wu J, Myerson JW, Marcos-Contreras OA, Katzen J, Carl JM, Morrisey EE, Cantu E, Villa CH, Mitragotri S, Muzykantov VR, Brenner JS. ACS Nano. 2022 Mar 22;16(3):4666-4683. doi: 10.1021/acsnano.1c11374. Epub 2022 Mar 10. PMID: 35266686 PMCID: PMC9339245

February 2022

• Chronic Sleep Deprivation Blocks Voluntary Morphine Consumption but Not Conditioned Place Preference in Mice. Eacret D, Lemchi C, Caulfield JI, Cavigelli SA, Veasey SC, Blendy JA. Front Neurosci. 2022 Feb 17;16:836693. doi: 10.3389/fnins.2022.836693. eCollection 2022. PMID: 35250468 PMCID: PMC8892254 
• Progerin mislocalizes myocardin-related transcription factor in Hutchinson-Guilford Progeria syndrome. von Kleeck R, Castagnino P, Assoian RK. Vasc Biol. 2022 Feb 15;4(1):1-10. doi: 10.1530/VB-21-0018. eCollection 2022 Feb 1. PMID: 35441125 PMCID: PMC9012937
• Cytomegalovirus latent infection is associated with an increased risk of COVID-19-related hospitalization. Alanio C, Verma A, Mathew D, Gouma S, Liang G, Dunn T, Oldridge DA, Weaver JE, Kuri-Cervantes L, Pampena MB; UPenn COVID Processing Unit, Betts MR, Collman RG, Bushman FD, Meyer NJ, Hensley SE, Rader D, Wherry EJ. J Infect Dis. 2022 Feb 2:jiac020. doi: 10.1093/infdis/jiac020. Online ahead of print. PMID: 35134186
• Decade-long leukaemia remissions with persistence of CD4 + CAR T cells. Melenhorst JJ, Chen GM, Wang M, Porter DL, Chen C, Collins MA, Gao P, Bandyopadhyay S, Sun H, Zhao Z, Lundh S, Pruteanu-Malinici I, Nobles CL, Maji S, Frey NV, Gill SI, Tian L, Kulikovskaya I, Gupta M, Ambrose DE, Davis MM, Fraietta JA, Brogdon JL, Young RM, Chew A, Levine BL, Siegel DL, Alanio C, Wherry EJ, Bushman FD, Lacey SF, Tan K, June CH. Nature. 2022 Feb 2. doi: 10.1038/s41586-021-04390-6. Online ahead of print. PMID: 35110735
• Consequences of prefrontal tDCS on inhibitory control and reactive aggression. Weidler C, Habel U, Wallheinke P, Wagels L, Hofhansel L, Ling S, Blendy JA, Clemens B. Soc Cogn Affect Neurosci. 2022 Feb 3;17(1):120-130. doi: 10.1093/scan/nsaa158. PMID: 33227131 
• Activating RAC1 variants in the switch II region cause a developmental syndrome and alter neuronal morphology. Banka S, Bennington A, Baker MJ, Rijckmans E, Clemente GD, Ansor NM, Sito H, Prasad P, Anyane-Yeboa K, Badalato L, Dimitrov B, Fitzpatrick D, Hurst ACE, Jansen AC, Kelly MA, Krantz I, Rieubland C, Ross M, Rudy NL, Sanz J, Stouffs K, Xu ZL, Malliri A, Kazanietz MG, Millard TH. Brain. 2022 Feb 9:awac049. doi: 10.1093/brain/awac049. Online ahead of print. PMID: 35139179
• Combating Complement's Deleterious Effects on Nanomedicine by Conjugating Complement Regulatory Proteins to Nanoparticles. Wang Z, Hood ED, Nong J, Ding J, Marcos-Contreras OA, Glassman PM, Rubey KM, Zaleski M, Espy CL, Gullipali D, Miwa T, Muzykantov VR, Song WC, Myerson JW, Brenner JS. Adv Mater. 2022 Feb;34(8):e2107070. doi: 10.1002/adma.202107070. Epub 2022 Jan 11. PMID: 34910334 PMCID: PMC9062787
• Multi-Trait Genome-Wide Association Study of Atherosclerosis Detects Novel Pleiotropic Loci. Bellomo TR, Bone WP, Chen BY, Gawronski KAB, Zhang D, Park J, Levin M, Tsao N, Klarin D, Lynch J, Assimes TL, Gaziano JM, Wilson PW, Cho K, Vujkovic M, O'Donnell CJ, Chang KM, Tsao PS, Rader DJ, Ritchie MD, Damrauer SM, Voight BF. Front Genet. 2022 Feb 2;12:787545. doi: 10.3389/fgene.2021.787545. eCollection 2021. PMID: 35186008 

January 2022

• Neuronal Yin Yang1 in the prefrontal cortex regulates transcriptional and behavioral responses to chronic stress in mice. Kwon DY, Xu B, Hu P, Zhao YT, Beagan JA, Nofziger JH, Cui Y, Phillips-Cremins JE, Blendy JA, Wu H, Zhou Z. Nat Commun. 2022 Jan 10;13(1):55. doi: 10.1038/s41467-021-27571-3. PMID: 35013139 
• The A118G single-nucleotide polymorphism in OPRM1 is a risk factor for asthma severity. Kawakami K, Miyasaka T, Nakamura Y, Metoki H, Miyata S, Sato M, Sora I, Yamauchi K, Kawakami K, Blendy JA, Kawano T, Shimokawa H, Takayanagi M, Ohno I, Takahashi T. Allergol Int. 2022 Jan;71(1):55-65. doi: 10.1016/j.alit.2021.08.006. Epub 2021 Oct 27. PMID: 34688555
• Live Cell Genomics: Cell-Specific Transcriptome Capture in Live Single Cells from Complex Tissues. Lee J, Eberwine J. Methods Mol Biol. 2022;2383:617-626. doi: 10.1007/978-1-0716-1752-6_40. PMID: 34766318
• Structure of the ancient TRPY1 channel from Saccharomyces cerevisiae reveals mechanisms of modulation by lipids and calcium. Ahmed T, Nisler CR, Fluck EC 3rd, Walujkar S, Sotomayor M, Moiseenkova-Bell VY. Structure. 2022 Jan 6;30(1):139-155.e5. doi: 10.1016/j.str.2021.08.003. Epub 2021 Aug 27. PMID: 34453887
• Supramolecular arrangement of protein in nanoparticle structures predicts nanoparticle tropism for neutrophils in acute lung inflammation. Myerson JW, Patel PN, Rubey KM, Zamora ME, Zaleski MH, Habibi N, Walsh LR, Lee YW, Luther DC, Ferguson LT, Marcos-Contreras OA, Glassman PM, Mazaleuskaya LL, Johnston I, Hood ED, Shuvaeva T, Wu J, Zhang HY, Gregory JV, Kiseleva RY, Nong J, Grosser T, Greineder CF, Mitragotri S, Worthen GS, Rotello VM, Lahann J, Muzykantov VR, Brenner JS. Nat Nanotechnol. 2022 Jan;17(1):86-97. doi: 10.1038/s41565-021-00997-y. Epub 2021 Nov 18. PMID: 34795440 PMCID: PMC8776575

December 2021

• Fluck EC, Pumroy RA, Moiseenkova-Bell VY. Production and purification of TRPV2 and TRPV5 for structural and functional studies. Methods Enzymol. 2021;653:49-74. PMID: 34099181
• Kim J, Hong G, Mazaleuskaya L, Hsu JC, Rosario-Berrios DN, Grosser T, Cho-Park PF, Cormode DP. Ultrasmall Antioxidant Cerium Oxide Nanoparticles for Regulation of Acute Inflammation. ACS Appl Mater Interfaces. 2021 Dec 29;13(51):60852-60864. doi: 10.1021/acsami.1c16126. Epub 2021 Dec 16. PMID: 34914872

• Lee Y, Field JM, Sehgal A. Circadian Rhythms, Disease and Chronotherapy. J Biol Rhythms. 2021 Dec;36(6):503-531. doi: 10.1177/07487304211044301. Epub 2021 Sep 22. PMID: 34547953

• Added to pre-existing inflammation, mRNA-lipid nanoparticles induce inflammation exacerbation (IE). Parhiz H, Brenner JS, Patel P, Papp TE, Shahnawaz H, Li Q, Shi R, Zamora M, Yadegari A, Marcos-Contreras OA, Natesan A, Pardi N, Shuvaev VV, Kiseleva R, Myerson J, Uhler T, Riley RS, Han X, Mitchell MJ, Lam K, Heyes J, Weissman D, Muzykantov V. J Control Release. 2021 Dec 22:S0168-3659(21)00680-5. doi: 10.1016/j.jconrel.2021.12.027. Online ahead of print. PMID: 34953981 

November 2021

• Kahn B, Apostolidis SA, Bhatt V, Greenplate AR, Kallish S, LaCava A, Lucas A, Meyer NJ, Negoianu D, Ogdie AR, Shashaty MGS, Takach PA, Zuroff L, Wherry EJ, Anesi GL. Multisystem Inflammation and Organ Dysfunction After BNT162b2 Messenger RNA Coronavirus Disease 2019 Vaccination. Crit Care Explor. 2021 Nov 5;3(11):e0578. PMID: 34765984 
• Abdel-Hakeem MS, Manne S, Beltra JC, Stelekati E, Chen Z, Nzingha K, Ali MA, Johnson JL, Giles JR, Mathew D, Greenplate AR, Vahedi G, Wherry EJ. Author Correction: Epigenetic scarring of exhausted T cells hinders memory differentiation upon eliminating chronic antigenic stimulation. Nat Immunol. 2021 Nov;22(11):1465. PMID: 34588688
• Brooks TG, Mrčela A, Lahens NF, Paschos GK, Grosser T, Skarke C, FitzGerald GA, Grant GR. Nitecap: An Exploratory Circadian Analysis Web Application. J Biol Rhythms. 2021 Nov 2:7487304211054408. PMID: 34724846
• Cooke M, Kreider-Letterman G, Baker MJ, Zhang S, Sullivan NT, Eruslanov E, Abba MC, Goicoechea SM, García-Mata R, Kazanietz MG. FARP1, ARHGEF39, and TIAM2 are essential receptor tyrosine kinase effectors for Rac1-dependent cell motility in human lung adenocarcinoma. Cell Rep. 2021 Nov 2;37(5):109905. PMID: 34731623 

October 2021

• Goel RR, Painter MM, Apostolidis SA, Mathew D, Meng W, Rosenfeld AM, Lundgreen KA, Reynaldi A, Khoury DS, Pattekar A, Gouma S, Kuri-Cervantes L, Hicks P, Dysinger S, Hicks A, Sharma H, Herring S, Korte S, Baxter AE, Oldridge DA, Giles JR, Weirick ME, McAllister CM, Awofolaju M, Tanenbaum N, Drapeau EM, Dougherty J, Long S, D'Andrea K, Hamilton JT, McLaughlin M, Williams JC, Adamski S, Kuthuru O; UPenn COVID Processing Unit‡, Frank I, Betts MR, Vella LA, Grifoni A, Weiskopf D, Sette A, Hensley SE, Davenport MP, Bates P, Luning Prak ET, Greenplate AR, Wherry EJ, Adamski S, Alam Z, Addison MM, Byrne KT, Chandra A, Descamps HC, Han N, Kaminskiy Y, Kammerman SC, Kim J, Greenplate AR, Hamilton JT, Markosyan N, Noll JH, Omran DK, Pattekar A, Perkey E, Prager EM, Pueschl D, Rennels A, Shah JB, Shilan JS, Wilhausen N, Vanderbeck AN. mRNA vaccines induce durable immune memory to SARS-CoV-2 and variants of concern. Science. 2021 Oct 14:eabm0829. PMID: 34648302
• Andrews LP, Vignali KM, Szymczak-Workman AL, Burton AR, Brunazzi EA, Ngiow SF, Harusato A, Sharpe AH, Wherry EJ, Taniuchi I, Workman CJ, Vignali DAA. A Cre-driven allele-conditioning line to interrogate CD4 + conventional T cells. Immunity. 2021 Oct 12;54(10):2209-2217.e6. PMID: 34551314
• Kawakami K, Miyasaka T, Nakamura Y, Metoki H, Miyata S, Sato M, Sora I, Yamauchi K, Kawakami K, Blendy JA, Kawano T, Shimokawa H, Takayanagi M, Ohno I, Takahashi T. The A118G single-nucleotide polymorphism in OPRM1 is a risk factor for asthma severity. Allergol Int. 2021 Oct 20:S1323-8930(21)00094-0. PMID: 34688555 
• Lucas A, Eberwine JH, Bagley SJ, Fan Y, Nasrallah MP, Brem S. Commentary: "Zooming in" on Glioblastoma: Understanding Tumor Heterogeneity and Its Clinical Implications in the Era of Single-Cell Ribonucleic Acid Sequencing. Neurosurgery. 2021 Oct 13;89(5):E262-E263. PMID: 34332498 
• Liu X, Verma A, Garcia G Jr, Ramage H, Lucas A, Myers RL, Michaelson JJ, Coryell W, Kumar A, Charney AW, Kazanietz MG, Rader DJ, Ritchie MD, Berrettini WH, Schultz DC, Cherry S, Damoiseaux R, Arumugaswami V, Klein PS. Targeting the coronavirus nucleocapsid protein through GSK-3 inhibition. Proc Natl Acad Sci U S A. 2021 Oct 19;118(42):e2113401118. PMID: 34593624

September 2021

• Lederer K, Parvathaneni K, Painter MM, Bettini E, Agarwal D, Lundgreen KA, Weirick M, Goel RR, Xu X, Drapeau EM, Gouma S, Greenplate AR, Coz CL, Romberg N, Jones L, Rosen M, Besharatian B, Kaminiski M, Weiskopf D, Sette A, Hensley SE, Bates P, Wherry EJ, Naji A, Bhoj V, Locci M. Germinal center responses to SARS-CoV-2 mRNA vaccines in healthy and immunocompromised individuals. medRxiv. 2021 Sep 21:2021.09.16.21263686. PMID: 34580676
• Apostolidis SA, Kakara M, Painter MM, Goel RR, Mathew D, Lenzi K, Rezk A, Patterson KR, Espinoza DA, Kadri JC, Markowitz DM, E Markowitz C, Mexhitaj I, Jacobs D, Babb A, Betts MR, Prak ETL, Weiskopf D, Grifoni A, Lundgreen KA, Gouma S, Sette A, Bates P, Hensley SE, Greenplate AR, Wherry EJ, Li R, Bar-Or A. Cellular and humoral immune responses following SARS-CoV-2 mRNA vaccination in patients with multiple sclerosis on anti-CD20 therapy. Nat Med. 2021 Sep 14. doi: 10.1038/s41591-021-01507-2. PMID: 34522051
• Chang SE, Feng A, Meng W, Apostolidis SA, Mack E, Artandi M, Barman L, Bennett K, Chakraborty S, Chang I, Cheung P, Chinthrajah S, Dhingra S, Do E, Finck A, Gaano A, Geßner R, Giannini HM, Gonzalez J, Greib S, Gündisch M, Hsu AR, Kuo A, Manohar M, Mao R, Neeli I, Neubauer A, Oniyide O, Powell AE, Puri R, Renz H, Schapiro J, Weidenbacher PA, Wittman R, Ahuja N, Chung HR, Jagannathan P, James JA, Kim PS, Meyer NJ, Nadeau KC, Radic M, Robinson WH, Singh U, Wang TT, Wherry EJ, Skevaki C, Luning Prak ET, Utz PJ. New-onset IgG autoantibodies in hospitalized patients with COVID-19. Nat Commun. 2021 Sep 14;12(1):5417. PMID: 34521836
• Chong EA, Alanio C, Svoboda J, Nasta SD, Landsburg DJ, Lacey SF, Ruella M, Bhattacharyya S, Wherry EJ, Schuster SJ. Pembrolizumab for B-cell lymphomas relapsing after or refractory to CD19-directed CAR T-cell therapy. Blood. 2021 Sep 9:blood.2021012634. PMID: 34496014
• Painter MM, Mathew D, Goel RR, Apostolidis SA, Pattekar A, Kuthuru O, Baxter AE, Herati RS, Oldridge DA, Gouma S, Hicks P, Dysinger S, Lundgreen KA, Kuri-Cervantes L, Adamski S, Hicks A, Korte S, Giles JR, Weirick ME, McAllister CM, Dougherty J, Long S, D'Andrea K, Hamilton JT, Betts MR, Bates P, Hensley SE, Grifoni A, Weiskopf D, Sette A, Greenplate AR, Wherry EJ. Rapid induction of antigen-specific CD4 + T cells is associated with coordinated humoral and cellular immunity to SARS-CoV-2 mRNA vaccination. Rapid induction of antigen-specific CD4+ T cells is associated with coordinated humoral and cellular immunity to SARS-CoV-2 mRNA vaccination. Immunity. 2021 Sep 14;54(9):2133-2142.e3. PMID: 34453880 
• Xu SJ, Lombroso SI, Fischer DK, Carpenter MD, Marchione DM, Hamilton PJ, Lim CJ, Neve RL, Garcia BA, Wimmer ME, Pierce RC, Heller EA. Chromatin-mediated alternative splicing regulates cocaine-reward behavior. Neuron. 2021 Sep 15;109(18):2943-2966.e8. PMID: 34480866
• Martino RA, Fluck EC 3rd, Murphy J, Wang Q, Hoff H, Pumroy RA, Lee CY, Sims JJ, Roy S, Moiseenkova-Bell VY, Wilson JM. Context-Specific Function of the Engineered Peptide Domain of PHP.B.  J Virol. 2021 Sep 27;95(20):e0116421. PMID: 34346767

August 2021

• Goel RR, Painter MM, Apostolidis SA, Mathew D, Meng W, Rosenfeld AM, Lundgreen KA, Reynaldi A, Khoury DS, Pattekar A, Gouma S, Kuri-Cervantes L, Hicks P, Dysinger S, Hicks A, Sharma H, Herring S, Korte S, Baxter AE, Oldridge DA, Giles JR, Weirick ME, McAllister CM, Awofolaju M, Tanenbaum N, Drapeau EM, Dougherty J, Long S, D'Andrea K, Hamilton JT, McLaughlin M, Williams JC, Adamski S, Kuthuru O; UPenn COVID Processing Unit, Frank I, Betts MR, Vella LA, Grifoni A, Weiskopf D, Sette A, Hensley SE, Davenport MP, Bates P, Luning Prak ET, Greenplate AR, Wherry EJ. mRNA Vaccination Induces Durable Immune Memory to SARS-CoV-2 with Continued Evolution to Variants of Concern. bioRxiv. 2021 Aug 23:2021.08.23.457229. PMID: 34462751 
• Merenstein C, Liang G, Whiteside SA, Cobián-Güemes AG, Merlino MS, Taylor LJ, Glascock A, Bittinger K, Tanes C, Graham-Wooten J, Khatib LA, Fitzgerald AS, Reddy S, Baxter AE, Giles JR, Oldridge DA, Meyer NJ, Wherry EJ, McGinniss JE, Bushman FD, Collman RG. Signatures of COVID-19 Severity and Immune Response in the Respiratory Tract Microbiome. mBio. 2021 Aug 31;12(4):e0177721. PMID: 34399607 
• Abdel-Hakeem MS, Manne S, Beltra JC, Stelekati E, Chen Z, Nzingha K, Ali MA, Johnson JL, Giles JR, Mathew D, Greenplate AR, Vahedi G, Wherry EJ. Epigenetic scarring of exhausted T cells hinders memory differentiation upon eliminating chronic antigenic stimulation. Nat Immunol. 2021 Aug;22(8):1008-1019. PMID: 34312545
• Elhalem E, Bellomo A, Cooke M, Scravaglieri A, Pearce LV, Peach ML, Gandolfi Donadío L, Kazanietz MG, Comin MJ. Design, Synthesis, and Characterization of Novel sn-1 Heterocyclic DAG-Lactones as PKC Activators.  J Med Chem. 2021 Aug 12;64(15):11418-11431. PMID: 34279947
• Ahmed T, Nisler CR, Fluck EC 3rd, Walujkar S, Sotomayor M, Moiseenkova-Bell VY. Structure of the ancient TRPY1 channel from Saccharomyces cerevisiae reveals mechanisms of modulation by lipids and calcium. Structure. 2021 Aug 24:S0969-2126(21)00298-7. PMID: 34453887
• Swanson NA, Lokareddy RK, Li F, Hou CD, Leptihn S, Pavlenok M, Niederweis M, Pumroy RA, Moiseenkova-Bell VY, Cingolani G. Cryo-EM structure of the periplasmic tunnel of T7 DNA-ejectosome at 2.7 Å resolution. Mol Cell. 2021 Aug 5;81(15):3145-3159.e7. PMID: 34214465
• Moiseenkova-Bell V, Delemotte L, Minor DL Jr. Ion Channels: Intersection of Structure, Function, and Pharmacology. J Mol Biol. 2021 Aug 20;433(17):167102. PMID: 34119491 

July 2021

• Alanio C, Wherry EJ. Subsetting the subsets: Heterogeneity and developmental relationships of T cells in human tumors. Sci Immunol. 2021 Jul 23;6(61):eabj3067. PMID: 34301801 
• Hou W, Ji Z, Chen Z, Wherry EJ, Hicks SC, Ji H. A statistical framework for differential pseudotime analysis with multiple single-cell RNA-seq samples. bioRxiv. 2021 Jul 12:2021.07.10.451910. PMID: 34282418 
• Carpenter MD, Manners MT, Heller EA, Blendy JA. Adolescent oxycodone exposure inhibits withdrawal-induced expression of genes associated with the dopamine transmission. Addict Biol. 2021 Jul;26(4):e12994. PMID: 33325096

June 2021

May 2021

April 2021

• Ray S, Valekunja UK, Stangherlin A, Howell SA, Snijders AP, Damodaran G, Reddy AB. Response to Comment on "Circadian rhythms in the absence of the clock gene Bmal1". Science 2021 Apr 16;372(6539):eabf1941. PMID: 33859003
• Goel RR, Apostolidis SA, Painter MM, Mathew D, Pattekar A, Kuthuru O, Gouma S, Hicks P, Meng W, Rosenfeld AM, Dysinger S, Lundgreen KA, Kuri-Cervantes L, Adamski S, Hicks A, Korte S, Oldridge DA, Baxter AE, Giles JR, Weirick ME, McAllister CM, Dougherty J, Long S, D'Andrea K, Hamilton JT, Betts MR, Luning Prak ET, Bates P, Hensley SE, Greenplate AR, Wherry EJ. Distinct antibody and memory B cell responses in SARS-CoV-2 naive and recovered individuals following mRNA vaccination. Sci Immunol 2021 Apr 15;6(58):eabi6950. PMID: 33858945
• Merenstein C, Liang G, Whiteside SA, Cobián-Güemes AG, Merlino MS, Taylor LJ, Glascock A, Bittinger K, Tanes C, Graham-Wooten J, Khatib LA, Fitzgerald AS, Reddy S, Baxter AE, Giles JR, Oldridge DA, Meyer NJ, Wherry EJ, McGinniss JE, Bushman FD, Collman RG. Signatures of COVID-19 severity and immune response in the respiratory tract microbiome. medRxiv. 2021 Apr 5:2021.04.02.21254514. PMID: 33851179.
• Yao C, Lou G, Sun HW, Zhu Z, Sun Y, Chen Z, Chauss D, Moseman EA, Cheng J, D'Antonio MA, Shi W, Shi J, Kometani K, Kurosaki T, Wherry EJ, Afzali B, Gattinoni L, Zhu Y, McGavern DB, O'Shea JJ, Schwartzberg PL, Wu T. Author Correction: BACH2 enforces the transcriptional and epigenetic programs of stem-like CD8+ T cells. Nat Immunol 2021 Apr;22(4):530. PMID: 33658708.
• Anderson EM, Goodwin EC, Verma A, Arevalo CP, Bolton MJ, Weirick ME, Gouma S, McAllister CM, Christensen SR, Weaver J, Hicks P, Manzoni TB, Oniyide O, Ramage H, Mathew D, Baxter AE, Oldridge DA, Greenplate AR, Wu JE, Alanio C, D'Andrea K, Kuthuru O, Dougherty J, Pattekar A, Kim J, Han N, Apostolidis SA, Huang AC, Vella LA, Kuri-Cervantes L, Pampena MB; UPenn COVID Processing Unit, Betts MR, Wherry EJ, Meyer NJ, Cherry S, Bates P, Rader DJ, Hensley SE. Seasonal human coronavirus antibodies are boosted upon SARS-CoV-2 infection but not associated with protection. Cell 2021 Apr 1;184(7):1858-1864.e10. PMID: 33631096 PMCID: PMC7871851
• Wherry EJ, Jaffee EM, Warren N, D'Souza G, Ribas A; AACR COVID-19 and Cancer Task Force. How Did We Get a COVID-19 Vaccine in Less Than 1 Year? Clin Cancer Res 2021 Apr 15;27(8):2136-2138. PMID: 33542081
• Baker MJ, Kazanietz MG. The anti-Rac1-GTP antibody and the detection of active Rac1: a tool with a fundamental flaw. Small GTPases. 2021 Apr 29:1-5. PMID: 33910489

March 2021

• Annabi N, Baker M, Boettiger A, Chakraborty D, Chen Y, Corbett KS, Correia B, Dahlman J, de Oliveira T, Ertuerk A, Yanik MF, Henaff E, Huch M, Iliev ID, Jacobs T, Junca H, Keung A, Kolodkin-Gal I, Krishnaswamy S, Lancaster M, Macosko E, Martínez-Núñez MA, Miura K, Molloy J, Cruz AO, Platt RJ, Posey AD Jr, Shao H, Simunovic M, Slavov N, Takebe T, Vandenberghe LH, Varshney RK, Wang J. Voice of biotech research. Nat Biotechnology 2021 Mar;39(3):281-286 PMID; 33692517
• Douglas B, Oyesola O, Cooper MM, Posey A, Wojno ET, Giacomin PR, Herbert DR. Immune System Investigation Using Parasitic Helminths. Annu Rev Immunol. 2021 Mar 1. Online ahead of print. PMID: 33646858
• Zhao Y, McVeigh BM, Moiseenkova-Bell VY. Structural Pharmacology of TRP Channels. J Mol Bio. 2021 Mar 5:166914. Online ahead of print. PMID: 33676926
• Rando HM, Wellhausen N, Ghosh S, Lee AJ, Dattoli AA, Hu F, Byrd JB, Rafizadeh DN, Qi Y, Sun Y, Field JM, Guebila MB, Jadavji NM, Lordan R, Skelly AN, Ramsundar B, Brueffer C, Wang J, Goel RR, Park Y, Consortium CR, Boca SM, Gitter A, Greene CS. Identification and Development of Therapeutics for COVID-19. ARXiv. 2021 Mar 3;ArXiv:2103.02723v1.  Preprint PMID: 33688554 PMID: PMC7941644
• Dang MT, Gonzalez MV, Gaonkar KS, Rathi KS, Young P, Arif S, Zhai L, Alam Z, Devalaraja S, To TKJ, Folkert IW, Raman P, Rokita JL, Martinez D, Taroni JN, Shapiro JA, Greene CS, Savonen C, Mafra F, Hakonarson H, Curran T, Haldar M. Macrophages in SHH subgourp medulloblastoma display dynamic heterogeneity that varies with treatment modality. Cell Rep. 2021 Mar 30;34(13):108917. PMID: 33789113
• Muroyama Y, Wherry EJ. Memory T-Cell Heterogeneity and Terminology. Cold Spring Harb Perspect Biol. 2021 Mar 29:a037929. Online ahead of print. PMID: 33782027
• Chuntova P, Chow F, Watchmaker PB, Galvez M, Heimberger AB, Newell EW, Diaz A, DePinho RA, Li MO, Wherry EJ, Mitchell D, Terabe M, Wainwright DA, Berzofsky JA, Herold-Mende C, Heath JR, Lim M, Margolin KA, Chiocca EA, Kasahara N, Ellingson BM, Brown CE, Chen Y, Fecci PE, Reardon DA, Dunn GP, Liau LM, Costello JF, Wick W, Cloughesy T, Timmer WC, Wen PY, Prins RM, Platten M, Okada H. Unique challenges for glioblastoma immunotherapy-discussions across neuro-oncology and non-neuro-oncology experts in cancer immunology. Meeting Report from the 2019 SNO Immuno-Oncology Think Tank. Neuro Oncol. 2021 Mar 25;23(3):356-375. PMID: 3367885
• Benallegue N, Kebir H, Kapoor R, Crockett A, Li C, Cheslow L, Abdel-Hakeem MS, Gesualdi J, Miller MC, Wherry EJ, Church ME, Blanco MA, Alvarez JI. The hedgehog pathway suppresses neuropathogenesis in CD4 T cell-driven inflammation. Brain. 2021 Mar 16:awab083. PMID: 33723591
• Goel RR, Apostolidis SA, Painter MM, Mathew D, Pattekar A, Kuthuru O, Gouma S, Kuri-Cervantes L, Meng W, Adamski S, Baxter AE, Giles JR, Weirick ME, McAllister CM, Hicks A, Korte S, Dougherty J, Long S, D'Andrea K, Hamilton JT, Prak ETL, Betts MR, Bates P, Hensley SE, Greenplate AR, Wherry EJ. Longitudinal Analysis Reveals Distinct Antibody and Memory B Cell Responses in SARS-CoV2 Naive and Recovered Individuals Following mRNA Vaccination. medRxiv. 2021 Mar 6:2021.03.03.21252872. PMID: 33688691
• Vella LA, Giles JR, Baxter AE, Oldridge DA, Diorio C, Kuri-Cervantes L, Alanio C, Pampena MB, Wu JE, Chen Z, Huang YJ, Anderson EM, Gouma S, McNerney KO, Chase J, Burudpakdee C, Lee JH, Apostolidis SA, Huang AC, Mathew D, Kuthuru O, Goodwin EC, Weirick ME, Bolton MJ, Arevalo CP, Ramos A, Jasen CJ, Conrey PE, Sayed S, Giannini HM, D'Andrea K; UPenn COVID Processing Unit, Meyer NJ, Behrens EM, Bassiri H, Hensley SE, Henrickson SE, Teachey DT, Betts MR, Wherry EJ. Deep immune profiling of MIS-C demonstrates marked but transient immune activation compared to adult and pediatric COVID-19. Sci Immunol 2021 Mar 2;6(57):eanf7570. PMID: 33653907
• Fraietta JA, Lacey SF, Orlando EJ, Pruteanu-Malinici I, Gohil M, Lundh S, Boesteanu AC, Wang Y, O'Connor RS, Hwang WT, Pequignot E, Ambrose DE, Zhang C, Wilcox N, Bedoya F, Dorfmeier C, Chen F, Tian L, Parakandi H, Gupta M, Young RM, Johnson FB, Kulikovskaya I, Liu L, Xu J, Kassim SH, Davis MM, Levine BL, Frey NV, Siegel DL, Huang AC, Wherry EJ, Bitter H, Brogdon JL, Porter DL, June CH, Melenhorst JJ. Author Correction: Determinants of response and resistance to CD19 chimeric antigen receptor (CAR) T cell therapy of chronic lymphocytic leukemia. Nat Med 2021 Mar;27(3):561. PMID: 33547459
• Chen Z, Arai E, Khan O, Zhang Z, Ngiow SF, He Y, Huang H, Manne S, Cao Z, Baxter AE, Cai Z, Freilich E, Ali MA, Giles JR, Wu JE, Greenplate AR, Hakeem MA, Chen Q, Kurachi M, Nzingha K, Ekshyyan V, Mathew D, Wen Z, Speck NA, Battle A, Berger SL, Wherry EJ, Shi J. In vivo CD8 + T cell CRISPR screening reveals control by Fli1 in infection and cancer. Cell 2021 Mar 4;184(5):1262-1280. PMID: 33636129 PMCID: PMC8054351
• Yao C, Lou G, Sun HW, Zhu Z, Sun Y, Chen Z, Chauss D, Moseman EA, Cheng J, D'Antonio MA, Shi W, Shi J, Kometani K, Kurosaki T, Wherry EJ, Afzali B, Gattinoni L, Zhu Y, McGavern DB, O'Shea JJ, Schwartzberg PL, Wu T. BACH2 enforces the transcriptional and epigenetic programs of stem-like CD8+ T cell. Nat Immunol 2021 Mar;22(3):370-380. PMID: 33574619.
• Brynildsen JK, Blendy JA. Linking the CHRNA5 SNP to drug abuse liability: From circuitry to cellular mechanisms. Neuropharmacology. 2021 Mar 15;186:108480. PMID: 33539855 

February 2021

• Mueller AC, Piper M, Goodspeed A, Bhuvane S, Williams JS, Bhatia S, Phan AV, Van Court B, Zolman KL, Peña B, Oweida AJ, Zakem S, Meguid C, Knitz MW, Darragh L, Bickett TE, Gadwa J, Mestroni L, Taylor MRG, Jordan KR, Dempsey P, Lucia MS, McCarter MD, Del Chiaro M, Messersmith WA, Schulick RD, Goodman KA, Gough MJ, Greene CS, Costello JC, Galvao Neto A, Lagares D, Hansen KC, Van Bokhoven A, Karam SD. Induction of ADAM10 by RT drives fibrosis, resistance, and EMT in pancreatic cancer. Cancer Res 2021 Feb 1:cannes. CAN-20-3892-A. 2020 Online ahead of print. PMID: 33526513
• Rando HM, MacLean AL, Lee AJ, Ray S, Bansal V, Skelly AN, Sell E, Dziak JJ, Shinholster L, McGowan LD, Guebila MB, Wellhausen N, Knyazev S, Boca SM, Capone S, Qi Y, Park Y, Sun Y, Mai D, Brueffer C, Byrd JB, Wang J, Lordan R, Velazquez R, Szeto GL, Barton JP, Goel RR, Mangul S, Lubiana T, Consortium CR, Gitter A, Greene CS. Pathogenesis, Symptomatology, and Transmission of SARS-CoV-2 through analysis of Viral Genomics and Structure. ArXiv. 2021 Feb 1:arXiv:2012.01521v2. Preprint. PMID: 33594340

January 2021

• Cousminer DL, Wagley Y, Pippin JA, Elhakeem A, Way GP, Pahl MC, McCormack SE, Chesi A, Mitchell JA, Kindler JM, Baird D, Hartley A, Howe L, Kalkwarf HJ, Lappe JM, Lu S, Leonard ME, Johnson ME, Hakonarson H, Gilsanz V, Shepherd JA, Oberfield SE, Greene CS, Kelly A, Lawlor DA, Voight BF, Wells AD, Zemel BS, Hankenson KD, Grant SFA. Genome-wide association study implicates novel loci and reveals candidate effector genes for longitudinal pediatric bone accrual. Genome Biol. 2021 Jan 4;22(1):1. PMID: 33397451
• Ch R, Rey G, Ray S, Jha PK, Driscoll PC, Dos Santos MS, Malik DM, Lach R, Weljie AM, MacRae JI, Valekunja UK, Reddy AB. Rhythmic glucose metabolism regulates the redox circadian clockwork in human red blood cells. Nat Commun. 2021 Jan 15;12(1):377. PMID: 33452240
• Meyer NJ, Lindell RB, Wherry EJ. Immune Stimulation With Recombinant Human Granulocyte Colony-Stimulating Factor for Coronavirus Disease 2019 (COVID-19)-Beware of Blind Spots. JAMA Intern Med. 2021 Jan 1;181(1):71-78. PMID: 32910179

Dec 2020

• Yong Zhang, Devon Collins, Eduardo Butelman, Julie Blendy and Mary Jeanne Kreek. Relapse-like behavior in a mouse model of the OPRM1 (mu-opioid receptor) A118G polymorphism: Examination with intravenous oxycodone self-administration. Neuropharmacology. 2020 Dec 15; 181:108351. PMID: 33031806
• Nilufar Rahimova, Mariana Cooke, Suli Zhang, Martin J Baker and Marcelo Kazanietz. The PKC universe keeps expanding: From cancer initiation to metastasis. Adv Biol Regul. 2020 Dec;78:100755. PMID: 33017725
• Rachana Garg, Mariana Cooke, Fernando Benavides, Martin C Abba, Michelle Cicchini, David Feldser and Marcelo Kazanietz. PKC ε Is Required for KRAS-Driven Lung Tumorigenesis. Cancer Res. 2020 Dec 1;80(23):5166-5173. PMID: 32994205.
• Anderson EM, Diorio C, Goodwin EC, McNerney KO, Weirick ME, Gouma S, Bolton MJ, Arevalo CP, Chase J, Hicks P, Manzoni TB, Baxter AE, Andrea KP, Burudpakdee C, Lee JH, Vella LA, Henrickson SE, Harris RM, Wherry EJ, Bates P, Bassiri H, Behrens EM, Teachey DT and Hensley SE.J. SARS-CoV-2 antibody responses in children with MIS-C and mild and severe COVID-19. Pediatric Infect Dis Soc. 2020 Dec 2:piaa161. PMID: 33263756

Nov 2020

• Yang Zhang, Yi Xu, Wenyun Lu, Jonathan M Ghergurovich, Lili Guo, Ian Blair, Joshua Rabinowitz and Xiaolu Yang. Upregulation of Antioxidant Capacity and Nucleotide Precursor Availability Suffices for Oncogenic Transformation. Cell Metab. 2020 Nov 6;S1550-4131(20)30535-0 PMID: 33159852.
• Carmen Weidler, Ute Habel, Paul Wallheinke, Lisa Wagels, Lena Hofhansel, Shichun Ling, Julie Blendy and Benjamin Clemens. Consequences Affect Neurosci 2020 Nov 23;nsaa158. PMID: 33227131.
• Suli Zhang, Marcelo G Kazanietz and Mariana Cooke. Rho GTPases and the emerging role of tunneling nanotubes in physiology and disease. Am J Physiol Cell Physiol. 2020 Nov 1;319(5):C877-C884. PMID: 32845720.
• Isabelle Lee, Guannan Zhang, Clementina Mesaros and Trevor Penning. Estrogen receptor-dependent and independent roles of benzo {a}pyrene in Ishikawa cells. J Endocrinol. 2020 Nov;247(2):139-151. PMID: 32992293 PMCID: PMC7534831.
• Zongmin Zhao, Anvay Ukidve, Vinu Krishnan, Alexandra Fehnel, Daniel C Pan, Yongsheng Gao, Jayoung Kim, Michael A Evans, Abhirup Mandal, Junling Guo, Vladimir R Muzykantov and Samir Mitragotri. Nat Biomed Eng. 2020 Nov 16. PMID: 33199847. 
• Oula Dagher, Tiffany King, Nils Wellhausen and Avery D Posey Jr. Combination Therapy for Solid Tumors: Taking a Classic CAR on New Adventures. Cancer Cell. 2020 Nov 9;38(5):621-623. PMID: 33064993. 
• Lisa N Bottalico and Aalim M Weljie. Cross-species physiological interactions of endocrine disrupting chemicals with circadian clock. Gen Comp Endocrinol. 2020 Nov 7;301:113650. PMID: 33166531.
• Sarah A Smith, Sayaka A Ogawa, Lillian Chau, Kelly Whelan, Kathryn E Hamilton, Jie Chen, Lu Tan, Eric Z Chen, Sue Keilbaugh, Franz Fogt, Meenakshi Bewtra, Jonathan Braun, Ramnik J Xavier, Clary B Clish, Barry Slaff, Aalim M Weljie, Frederic D Bushman, James D Lewis, Hongzhe Li, Stephen R Master, Michael Bennett, Hiroshi Nakagawa and Gary D Wu. Mitochondrial dysfunction in inflammatory bowel disease alters intestinal epithelial metabolism of hepatic acylcarnitines. J Clin Invest. 2020 Nov 3;133371. PMID: 33141762.
• Anderson EM, Goodwin EC, Verma A, Arevalo CP, Bolton MJ, Weirick ME, Gouma S, McAllister CM, Christensen SR, Weaver J, Hicks P, Manzoni TB, Oniyide O, Ramage H, Mathew D, Baxter AE, Oldridge DA, Greenplate AR, Wu JE, Alanio C, D'Andrea K, Kuthuru O, Dougherty J, Pattekar A, Kim J, Han N, Apostolidis SA, Huang AC, Vella LA, Wherry EJ, Meyer NJ, Cherry S, Bates P, Rader DJ, Hensley SE. Seasonal human coronavirus antibodies are boosted upon SARS-CoV-2 infection but not associated with protection. medRxiv. 2020 Nov 10:2020.11.06.20227215. PMID: 33200143 

Oct 2020

• Julia Brynildsen, Victoria Sanchez, Nicole L Yohn, Marco D Carpenter and Julie A Blendy. Sex-specific transgenerational effects of morphine exposure on reward and affective behaviors. Behav Brains Res. 2020 Oct 1;395-112842. PMID: 32745660.
• Sean B Yeldell, Linlin Yang, Jaehee Lee, James H Eberwine and Ivan J Dmochowski. Oligonucleotide Probe for Transcriptome in Vivo Analysis (TIVA) of Single Neurons with Minimal Background. ACS Chem Biol. 2020 Oct 16;15(10):2717-2721. PMID: 32902259.
• Samantha R Eck, Song-Jun Xu, Alexander Telenson, Michael R Duggan, Robert Cole, Brittany Wicks, Joy Bergmann, Hanna Lefebo, Marni Shore, Katherine A Shepard, Michael Akins, Vinay Parikh, Elizabeth Heller and Debra Bangasser. Stress Regulation of Sustained Attention and the Cholinergic Attention System. Biol Psychiatry. 2020 Oct 1;88(7):566-575. PMID: 32600739 PMCID: PMC7487022.
• Kevin Parker, Denis Migliorini, Eric Perkey, Kathryn Yost, Aparna Bhaduri, Puneet Bagga, Mohammad Haris, Neil Wilson, Fang Liu, Khatuna Gabunia, John Scholler, Thomas Montine, Vijay Bhoj, Ravinder Reddy, Suyash Mohan, Ivan Maillard, Amold Kriegstein, Carl June, Howard Chang, Avery Posey Jr and Ansuman Satpathy. Single-Cell Analysis Identify Brain Mural Cells Expressing CD19 as Potential Off-Tumor Targets for CAR-T Immunotherapies. Cell. 2020 Oct 1;183(1):126-142. PMID: 32961131 PMCID: PMC7640763.
• Jutamas Shaughnessy, Y Tran, Bo Zheng, Rosane DeOliveira, Sunita Gulati, Wen-Chao Song, James Maclean, Keith Wycoff and Sanjay Ram. Development of Complement Factor H-Based Immunotherapeutic Molecules in Tobacco Plants Against Multidrug-Resistant Neisseria gonorrhoeae. Front Immunol. 2020 Oct 26; 11:583305. PMID: 33193396 PMCID: PMC7649208. 

Sep 2020

• Robinson Shivon, Jones Alonzo, Brynildsen Julia, Ehrlich Michelle and Blendy Julie. Neurobehavioral effects of neonatal opioid exposure in mice: Influence of the OPRM1 SNP, Addict Biol. 2020 Sep; 25(5):e12806. doi: 10.1111/adb.12806.  Epub 2019 Jul 2. PMID: : 31267641
• Linlin Yang, James Eberwine and Ivan J Dmochowski. Capase-Activated Oligonucleotide Probe. Bioconjug Chem. 2020 Sep 16;31(9):2172-2178. PMID: 32786369
• Ronan Lordan, Garret A FitzGerald and Tilo Grosser. Reopening schools during COVID-19. Science. 2020 Sep 4;369(6508):1146. PMID: 32883837.
• Liwei Weng, Laurent Laboureur, Qingqing Wang, Lili Guo, Penning Xu, Leah Gottleib, David Lynch, Clementina Mesaros and Ian Blair. Extra-mitochondrial mouse frataxin and its implications for mouse models of Friedreich's ataxia. Sci Rep. 2020 Sep 25;10(1):15788. PMID: 32978498 PMCID: PMC7519113.

• Prasanna M Chandramouleeswaran, Manti Guha, Masataka Shimonosono, Kelly A Whelan, Hisatsugu Maekawa, Uma M Sachdeva, Gordon Ruthel, Sarmistha Mukherjee, Noah Engel, Michael V Gonzalez, James Garifallou, Shinya Ohashi, Andres J Klein-Szanto , Clementina A Mesaros, Ian A Blair, Renata Pellegrino da Silva, Hakon Hakonarson, Eishi Noguchi, Joseph A Baur and Hiroshi Nakagawa. Autophagy mitigates ethanol-induced mitochondrial dysfunction and oxidative stress in esophageal keratinocytes. PLos One. 2020 Sep 23; 15(9):e0239625. PMID: 32966340. PMCID: PMC7510980.

• Miriam Merad, Avery Posey Jr., Ofelia Olivero, Pankaj Singh, Ghassan Mouneimne, Lingyin Li, LaShanale Wallace and Tikvah Hayes. Diversity is a Strength of Cancer Research in the U.S. Cancer Cell. 2020 Sep 14;38(3):297-300.

• Sandipan Ray and Akhilesh Reddy. COVID-19 management in light of the circadian clock. Nat Rev Mol Cell Biol. 2020 Sept;21(9):494-495. PMID: 32699357.

• Vella L, Giles JR, Baxter AE, Oldridge DA, Diorio C, Alanio C, Pampena MB, Wu JE, Chen Z, Huang YJ, Anderson EM, Gouma S, McNerney KO, Chase J, Burudpakdee C, Lee JH, Apostolidis SA, Huang AC, Mathew D, Kuthuru O, Goodwin EC, Weirick ME, Bolton MJ, Arevalo CP, Ramos A, Jasen C, Giannini HM, DAndrea K, Meyer NJ, Behrens EM, Bassiri H, Hensley SE, Henrickson SE, Teachey DT, Betts MMR and Wherry EJ. Deep Immune Profiling of MIS-C demonstrates marked but transient immune activation compared to adult and pediatric COVID-19. medRxiv. 2020 Sep 27:2020.09.25.20201863. doi: 10.1101/2020.09.25.20201863. PMID: 32995826

• Meyer NJ, Lindell RB, Wherry EJ. Immune Stimulation With Recombinant Human Granulocyte Colony-Stimulating Factor for Coronavirus Disease 2019 (COVID-19)-Beware of Blind Spots. JAMA Intern Med. 2020 Sep 10. doi: 10.1001 PMID: 32910155 

Aug 2020

• Theken KN, Lee CR, Gong L, Caudle KE, Formea CM, Gaedigk A, Klein TE, Agúndez JAG, Grosser T. Clinical Pharmacogenetics Implementation Consortium Guideline (CPIC) for CYP2C9 and Nonsteroidal Anti-Inflammatory Drugs. Clin Pharmacol Ther 2020 Aug;108(2):191-200.  doi: 10.1002/cpt.1830.  Epub 2020 Apr 28. PMID: 32189324
• Anderson EM, Diorio C, Goodwin EC, McNerney KO, Weirick ME, Gouma S, Bolton MJ, Arevalo CP, Chase J, Hicks P, Manzoni TB, Baxter AE, Andrea KP, Burudpakdee C, Lee JH, Vella LA, Henrickson SE, Harris RM, Wherry EJ, Bates P, Bassiri H, Behrens EM, Teachey DT, Hensley SE. SARS-CoV-2 antibody responses in children with MIS-C and mild and severe COVID-19. medRxiv. 2020 Aug 18:2020.08.17.20176552. PMID: 32839782 

July 2020

June 2020

May 2020

• Collins D, Zhang Y, Blendy J and Kreek MJ. Murine model of OPRM1 A118G alters oxycodone self-administration and locomotor activation, but not conditioned place preference. Neuropharmacology. 2020 May 1; 167:107864. doi:10/1016/jneuropharm.2019.107864. Epub 2019 Nov 25. PMID: 31778689

April 2020

• Han L, Choudhury S, Mich-Basso JD, Ammanamanchi N, Ganapathy B, Suresh S, Khaladkar M, Singh J, Maehr R, Zuppo DA, Kim J, Eberwine JE, Wyman SK, Wu YL and Kühn B. Lamin B2 Levels Regulate Polyploidization of Cardiomyocyte Nuclei and Myocardial Regeneration. Dev Cell. 2020 Apr 6;53(1):42-59.e11.  doi: 10.1016/j.devcel.2020.01.030.  Epub 2020 Feb 27. PMID: 32109383  PMCID: PMC7346764

March 2020

Feb 2020

Jan 2020

Dec 2019

Nov 2019

• Lin YHT, Way GP, Barwick BG, Mariano MC, Marcoulis M, Ferguson ID, Driessen C, Boise LH, Greene CS, Wiita AP. Integrated phosphoproteomics and transcriptional classifiers reveal hidden RAS signaling dynamics in multiple myeloma. Blood Adv. 2019 Nov 12;3(21):3214-3227.  doi: 10.1182/bloodadvances.2019000303. PMID: 31698452 PMCID: PMC6855123
• Llorens MC, Rossi FA, Garcia IA, Cooke M, Abba MC, Lopez-Haber C, Barrio-Real L, Vaglienti MV, Rossi M, Bocco JL, Kazanietz MG, Soria G. PKCα Modulates Epithelial-to-Mesenchymal Transition and Invasiveness of Breast Cancer Cells Through ZEB1. Front Oncol  2019 Nov 27;9:1323.  doi: 10.3389/fonc.2019.01323.  eCollection 2019.  PMID: 31828042  PMCID: PMC6890807
• Weng L, Wang Q, Yu S, Yang X, Lynch DR, Mesaros C, Blair IA. Evaluation of antibodies for western blot analysis of frataxin protein isoforms. J Immunol Methods 2019 Nov;474:112629.  doi: 10.1016/j.jim.2019.07.001.  Epub 2019 Jul 4. PMID: 31279523  PMCID: PMC6829029. 

Oct 2019

• Manners MT, Brynildsen JK, Schechter M, Liu X, Eacret D and Blendy JA. CREB deletion increases resilience to stress and downregulates inflammatory gene expression in the hippocampus. Brain Behav Immun. 2019 Oct;81:388-398.  doi: 10.1016/j.bbi.2019.06.035.  Epub 2019 Jun 27.
• Anikeeva Polina,  Boyden Edward, Brangwynne Clifford, Cissé Ibrahim I., Fiehn Oliver, Fromme Petra, Gingras Anne-Claude, Greene Casey S., Heard Edith, et al. Voices in methods development. Nat Methods. 2019 October ; 16(10): 945–951. doi:10.1038/s41592-019-0585-6. PMID: 31562479  PMCID: PMC7075469
• Mews P, Egervari G, Nativio R, Sidoli S, Donahue G, Lombroso SI, Alexander DC, Riesche SL, Heller EA, Nestler EJ, Garcia BA, Berger SL. Alcohol metabolism contributes to brain histone acetylation. Nature 2019 Oct;574(7780):717-721.  doi: 10.1038/s41586-019-1700-7.  Epub 2019 Oct 23. PMID: 31645761  PMCID: PMC6907081
• Lopez Soto EJ, Gandal MJ, Gonatopoulos-Pournatzis T, Heller EA, Luo D, Zheng S. Mechanisms of Neuronal Alternative Splicing and Strategies for Therapeutic Interventions. J Neurosci 2019 Oct 16;39(42):8193-8199.  doi: 10.1523/JNEUROSCI.1149-19.2019. PMID: 31619487  PMCID: PMC6794923
• Gajewski PA, Eagle AL, Williams ES, Manning CE, Lynch H, McCornack C, Maze I, Heller EA, Robinson AJ.  Epigenetic Regulation of Hippocampal Fosb Expression Controls Behavioral Responses to Cocaine. J Neurosci 2019 Oct 16;39(42):8305-8314.  doi: 10.1523/JNEUROSCI.0800-19.2019. Epub 2019 Sep 2. PMID: 31477569  PMCID: PMC6794929

Sept 2019

• Weidler C, Wagels L, Regenbogen C, Hofhansel L, Blendy JA, Clemens B, Montag C and Habel U. The influence of the OPRM1 (A118G) polymorphism on behavioral and neural correlates of aggression in healthy males. Neuropharmacology. 2019 Sep 15;156:107467.  doi: 10.1016/j.neuropharm.2018.12.014. Epub 2018 Dec 12. PMID: 30552906
• Theken KN, Hersh EV, Lahens NF, Lee HM, Li X, Granquist EJ, Giannakopoulos HE, Levin LM, Secreto SA, Grant GR, Detre JA, FitzGerald GA, Grosser T, Farrar JT. Variability in the Analgesic Response to Ibuprofen Is Associated With Cyclooxygenase Activation in Inflammatory Pain. Clin Pharmacol Ther 2019 Sep;106(3):632-641.  doi: 10.1002/cpt.1446. Epub 2019 Apr 29. PMID: 30929268  PMCID: PMC6753944
• Aljagthmi AA, Hill NT, Cooke M, Kazanietz MG, Abba MC, Long W, Kadakia MP.  ΔNp63α suppresses cells invasion by downregulating PKCγ/Rac1 signaling through miR-320a. Cell Death Dis 2019 Sep 12;10(9):680.  doi: 10.1038/s41419-019-1921-6. PMID: 31515469  PMCID: PMC6742631
• Pumroy RA, Samanta A, Liu Y, Hughes TE, Zhao S, Yudin Y, Rohacs T, Han S, Moiseenkova-Bell VY. Molecular mechanism of TRPV2 channel modulation by cannabidiol. Elife 2019 Sep 30;8:e48792.  doi: 10.7554/eLife.48792. PMID: 31566564  PMCID: PMC6794088

Aug 2019

July 2019

• Popova D, Desai N, Blendy JA and Pang ZP. Synaptic Regulation by OPRM1 Variants in Reward Neurocircuitry, J Neuroscience 2019 Jul 17; 39(29)"5685-5696. doi: 10.1523/JNEUROSCI.2317-18.2019. Epub 2019 May 20. PMID 31109961 PMCID: PMC6636083
• Kazanietz M, Durando M, Cooke M. CXCL13 and Its Receptor CXCR5 in Cancer: Inflammation, Immune Response, and Beyond. Front Endocrinol (Lausanne) 2019 Jul 12;10:471.  doi: 10.3389/fendo.2019.00471. eCollection 2019. PMID: 31354634  PMCID: PMC6639976
• Casado-Medrano V, Barrio-Real L, Wang A, Cooke M, Lopez-Haber C, Kazanietz M. Distinctive requirement of PKCε in the control of Rho GTPases in epithelial and mesenchymally transformed lung cancer cells. Oncogene 2019 Jul;38(27):5396-5412.  doi: 10.1038/s41388-019-0796-4.  Epub 2019 Mar 28. PMID: 30923343  PMCID: PMC6609469

June 2019

May 2019

• Brankovic S, Hawthorne EA, Yu X, Zhang Y, Assoian RK., MMP12 preferentially attenuates axial stiffening of aging arteries. J Biomech Eng. 2019 141(8) 081004-1 - 9. PMID: 30917195  
• Taroni JN, Grayson PC, Hu Q, Eddy S, Kretzier M, Merkel PA, Greene CS. MultiPLIER: A Transfer Learning Framework for Transcriptomics Reveals Systemic Features of Rare Disease. Cell Syst. 2019 May 22;8(5):380-394.e4.  doi: 10.1016/j.cels.2019.04.003. PMID: 31121115  PMCID: PMC6538307

April 2019

• Lee Y, Lahens NF, Zhang S, Bedont J, Field JM, Seghal A. G1/S cell cycle regulators mediate effects of circadian dysregulation on tumor growth and provide targets for timed anticancer treatment. PLoS Biol. 2019 Apr 30;17(4):e3000228.  doi: 10.1371/journal.pbio.3000228. eCollection 2019 Apr. PMID: 31039152  PMCID: PMC6490878

March 2019

• Del Campo L, Sánchez-López A, Salaices M, von Kleeck RA, Expósito E, González-Gómez C, Cussó L, Guzmán-Martínez G, Ruiz-Cabello J, Desco M, Assoian RK, Briones AM, Andrés V. Vascular smooth muscle cell-specific progerin expression in a mouse model of Hutchinson-Gilford progeria syndrome promotes arterial stiffness: Therapeutic effect of dietary nitrite. Aging Cell 2019 Mar 18 PMID: 30884114 
• Furman R, Axelsen PH. The effects of omega-3 fatty acid deficiency during development on oxidative fatty acid degradation during maturity in a mouse model of Alzheimer's disease. Neurobiol Aging 2019 Mar 23; 79:66-74 PMID: 31029017
• Huss DJ, Saias S, Hamamah S, Singh JM, Wang J, Dave M, Kim J, Eberwine J, Lansford R. Avian Primordial Germ Cells Contribute to and Interact With the Extracellular Matrix During Early Migration. Front Cell Dev Biol. 2019 Mar 28;7:35.  doi: 10.3389/fcell.2019.00035.  eCollection 2019. PMID: 30984757  PMCID: PMC6447691