Wang L, Hubbard RA, Walker RL, Lee EB, Larson EB, Crane PK. Assessing robustness of hazard ratio estimates to outcome misclassification in longitudinal panel studies with application to Alzheimer's disease. PLoS One, 12(12): E0190107, 2017.

Irwin DJ, McMillan CT, Xie SX, Rascovsky K, Van Deerlin VM, Coslett HB, Hamilton R, Aguirre G, Lee EB, Lee VMY, Trojanowski JQ, Grossman M. Asymmetry of post-mortem neuropathology in behavioural-variant frontotemporal dementia. Brain, 2017.

Phillips JS, Da Re F, Dratch L, Xie SX, Irwin DJ, McMillan CT, Vaishnavi SN, Ferrarese C, Lee EB, Shaw LM, Trojanowski JQ, Wolk DA, Grossman M. Neocortical origina and progression of gray matter atrophy in nonamnestic Alzheimer's disease. Neurobiol Aging 63: 75-87, 2017.

Yousef A, Robinson JL, Irwin DJ, Byrne MD, Kwong LK, Lee EB, Xu Y, Xie SX, Rennert L, Suh E, Van Deerlin VM, Grossman M, Lee VM, Trojanowski JQ. Neuron loss and degeneration in the progression of TDP-43 in frontotemporal lobar degeneration. Acta Neuropathologica Communications 5(1): 68, 2017.

Irwin DJ, Lleo A, Xie SX, McMillan CT, Wolk DA, Lee EB, Van Deerlin VM, Shaw LM, Trojanowski JQ, Grossman M. Ante mortem cerebrospinal fluid tau levels correlate with postmortem tau pathology in frontotemporal lobar degeneration. Ann Neurol 82(2): 247-258, 2017.

Paolicelli RC, Jawaid A, Henstridge CM, Valeri A, Merlini M, Robinson JL, Lee EB, Rose J, Appel S, Lee VM, Trojanowski JQ, Spires-Jones T, Schulz PE, Rajendran L. TDP-43 depletion in microglia promotes amyloid clearance but also induces synapse loss. Neuron 95(2): 297-308, 2017.

Kovacs GG et al., Multisite assessment of aging-related tau astrogliopathy (ARTAG). JNEN, 76(7): 605-619, 2017.

Giannini LAA, Irwin DJ, McMillan CT, Ash S, Rascovsky K, Wolk DA, Van Deerlin VM, Lee EB, Trojanowski JQ, Grossman M. Clinical markers for Alzheimer disease pathology in logopenic primary progressive aphasia. Neurology, 2017.

Bonini NM, Lee EB, Wasco W, Roses AD. Editorial overview: Molecular & genetic basis of disease. Curr Opin Genet Dev, 2017.

Liu EY, Cali CP, Lee EB. RNA metabolism in neurodegenerative disease. Disease Models & Mechanisms, 10: 509-518, 2017.

Kovacs GG, Robinson JL, Xie SX, Lee EB, Grossman M, Wolk DA, Irwin DJ, Weintraub D, Kim CF, Schuck T, Yousef A, Wagner ST, Suh E, Van Deerlin VM, Lee VM, Trojanowski JQ. Evaluating the patterns of aging-related tau astrogliopathy unravels novel insights into brain aging and neurodegenerative diseases. JNEN, 76(4): 270-788, 2017.

Jefferson-George KS, Wolk DA, Lee EB, McMillan CT. Cognitive decline associated with pathological burden in primary age-related tauopathy. Alzheimers Dement, in press, 2017.

Lee EB*, Porta S, Baer GM, Xu Y, Suh E, Kwong LK, Elman L, Grossman M, Lee VM-Y, Irwin DJ, VanDeerlin VM, Trojanowski JQ. Expansion of the classification of FTLD-TDP: Distinct pathology associated with rapidly progressive frontotemporal degeneration. Acta Neuropathologica, in press, 2017. *Corresponding author

Spotorno N, McMillan CT, Irwin DJ, Clark R, Lee EB, Trojanowski JQ, Weintraub D, Grossman M. Decision-making deficits associated with amyloidosis in Lewy body disorders. Front Hum Neurosci, 10: 693, 2017

Irwin DJ, Grossman M, Weintraub D, Hurtig HI, Duda JE, Xie SX, Lee EB, Van Deerlin VM, Lopez OL, Kofler JK, Nelson PT, Jicha GA, Woltjer R, Quinn JF, Kaye J, Leverenz JB, Tsuang D, Longfellow K, Yearout D, Kukull W, Keene CD, Montine TJ, Zabetian CP, Trojanowski JQ. Neuropathological and genetic correlates of survival and dementia onset in synucleinopathies: a retrospective analysis. Lancet Neurology, 16(1): 55-65, 2017.

Kovacs GG, Kwong LK, Grossman M, Irwin DJ, Lee EB, Robinson JL, Suh E, Van Deerlin VM, Lee VM, Trojanowski JQ. Tauopathy with hippocampal 4-repeat tau immunoreactive spherical inclusions: a report of three cases. Brain Pathol, in press, 2017.


McMillan CT, Irwin DJ, Nasrallah I, Phillips JS, Spindler M, Rascovsky K, Ternes K, Jester C, Wolk DA, Kwong LK, Lee VM, Lee EB, Trojanowski JQ, Grossman M. Multimodal evaluation demonstrates in vivo 18F-AV-1451 uptake in autopsy-confirmed coritcobasal degeneraion. Acta Neuropathologica, 132(6): 935-937, 2016.

Placek K, Massimo L, Olm C, Ternes K, Firn K, Van Deerlin V, Lee EB, Trojanowski JQ, Lee VM, Irwin D, Grossman M, McMillan CT. Congitive reserve in frontotemporal degeneration: Neuroanatomic and neuropsychological evidence. Neurology, 87(17): 1813-1819, 2016.

McMillan CT, Boyd C, Gross RG, Weinstein J, Firn K, Toledo JB, Rascovsky K, Shaw L, Wolk DA, Irwin DJ, Lee EB, Trojanowski JQ, Grossman M. Multimodal imaging evidence of pathology-mediated distribution in corticobasal syndrome. Neurology, 87(12): 1227-34, 2016.

Toledo JB, Gopal P, Raible K, Irwin DJ, Brettschneider J, Sedor S, Waits K, Boluda S, Grossman M, Van Deerlin VM, Lee EB, Arnold SE, Duda JE, Hurtig H, Lee VM, Adler CH, Beach TG, Trojanowski JQ. Pathological alpha-synuclein distribution in subjects with coincident Alzheimer's and Lewy body pathology. Acta Neuropathologica, 131(3): 393-409, 2016.

Kovacs GG, et al. Aging-related tau astrogliopathy (ARTAG): Harmonized evaluation strategy. Acta Neuropathologica. 131(1): 87-102, 2016.

Irwin DJ, Brettschneider J, McMillan CT, Cooper F, Olm C, Arnold SE, Van Deerlin VM, Seeley WW, Miller BL, Lee EB, Lee VM, Grossman M, Trojanowski JQ. Deep clinical and neuropathological phenotyping of Pick's disease. Annals of Neurology, 79(2): 272,87, 2016.

Montine TJ, Monsell SE, Beach TG, Bigio EH, Bu Y, Cairns NJ, Frosch M, Henriksen J, Kofler J, Kukull WA, Lee EB, Nelson PT, Schantz AM, Schneider JA, Sonnen JA, Trojanowski JQ, Vinters HV, Zhou XH, Hyman BT. Multisite assessment of NIA-AA guidelines for the neuropathologic evaluation of Alzheimer's disease. Alzheimers Dement 12(2): 164-9, 2016.

Iwrin DJ, Byrne MD, McMillan CT, Cooper F, Arnold SE, Lee EB, Van Deerlin VM, Xie SX, Lee VM, Grossman M, Trojanowski JQ. Semi-automated image analysis of Pick's disease and TDP-43 proteinopathy. J Histochem Cytochem. 64(1): 54-66, 2016.


O'Rourke JG, Bogdanik L, Muhammad AKMG, Gendron TF, Kim KJ, Austin A, Day J, Liu EY, Zarrow J, Grant S, Ho R, Bell S, Carmona S, Simpkinson M, Lall D, Wu K, Daughrity L, Dickson DW, Harms MB, Petrucelli L, Lee EB, Lutz CM, Baloh RH. C9orf72 BAC transgenic mice display typical pathologic features of ALS/FTD. Neuron. 88(5): 892-901, 2015.

Amlie-Wolf A, Ryvkin P, Tong R, Dragomir I, Suh E, Xu Y, Van Deerlin VM, Gregory BD, Kwong LK, Trojanowski JQ, Lee VMY, Wang LS, Lee EB. Transcriptomic changes due to cytoplasmic TDP-43 expression reveal dysregulation of histone transcripts and nuclear chromatin. PLoS One. 10(10): e0141836, 2015.

Montine TJ, Monsell SE, Beach TG, Bigio EH, Bu Y, Cairns NJ, Frosch M, Henriksen J, Kofler J, Kukull WA, Lee EB, Nelson PT, Schantz AM, Schneider JA, Sonnen JA, Trojanowski JQ, Vinters HV, Zhou XH, Hyman BT. Multisite assessment of NIA-AA guidelines for the neuropathologic evaluation of Alzheimer's disease. Alzheimers Dement. In press, 2015.

Robinson JL, Suh E, Wood EM, Lee EB, Coslett HB, Raible K, Lee VM, Trojanowski JQ, Van Deerlin VM. Common neuropathological features underlie distinct clinical presentations in three siblings with hereditary diffuse leukoencephalopathy with spheroids caused by CFS1R p.Arg782His. Acta Neuropathol Commun. 3(1): 42, 2015.

Suh E*, Lee EB*, Neal D, Wood EM, Toledo JB, Rennert L, Irwin DJ, McMillan CT, Krock B, Elman LB, McCluskey LF, Grossman M, Xie SX, Trojanowski JQ, Van Deerlin VM. Semi-automated quantification of C9orf72 expansion size reveals inverse correlation between hexanucleotide repeat number and disease duration in frontotemporal degeneration. Acta Neuropathologica, 130(3): 363-72, 2015. *Co-lead authors

McMillan CT, Russ J, Wood EM, Irwin DJ, Grossman M, McCluskey L, Elman L, Van Deerlin V, Lee EB. C9orf72 promoter hypermethylation is neuroprotective: Neuroimaging and neuropathologic evidence. Neurology. 84(16): 1622-30, 2015.

Irwin DJ, Cairns NJ, Grossman M, McMillan CT, Lee EB, Van Deerlin VM, Lee VM, Trojanowski JQ. Frontotemporal lobar degeneration: defining phenotyping diversity thorugh personalized medicine. Acta Neuropathologica. 129(4): 469-91, 2015.

Russ J, Liu EY, Wu K, Neal D, Suh E, Irwin DJ, McMillan CT, Harms MB, Cairns NJ, Wood EM, Xie SX, Elman L, McCluskey L, Grossman M, Van Deerlin VM, Lee EB. Hypermethlation of repeat expanded C9orf72 is a clinical and molecular disease modifier. Acta Neuropathologica. 129(1): 39-52, 2015.


McGurk L, Lee VM, Trojanowski JQ, Van Deerlin VM, Lee EB, Bonini NM. Poly-A binding protein-1 localization to a subset of TDP-43 inclusions in amyotrophic lateral sclerosis occurs more frequently in patients harboring an expansion in C9orf72. Journal of Neuropathology and Experimental Neurology. 73(9): 837-45, 2014

Yarchoan M, Toledo JB, Lee EB, Arvanitakis Z, Kazi H, Han LY, Louneva N, Lee VM, Kim SF, Trojanowski JQ, Arnold SE. Abnormal serine phosphorylation of insulin receptor substrate-1 is associated with tau pathology in Alzheimer's disease and tauopathies. Acta Neuropathologica. 128(5): 679-89, 2014

Robinson JL, Molina-Porcel L, Corrada MM, Raible K, Lee EB, Lee VM, Kawas CH, Trojanowski JQ. Perforant path synaptic loss correlates with cognitive impairment and Alzheimer's disease in the oldest-old. Brain. 137(9): 2578-87, 2014

Boluda S, Toledo JB, Irwin DJ, Raible KM, Byrne MD, Lee EB, Lee VM, Trojanowski JQ. A comparison of Abeta amyloid pathology staging systems and correlation with clinical diagnosis. Acta Neuropathologica. 128(4): 543-50, 2014

BrettschneiderJ, Arai K, Del Tredici K, Toledo JB, Robinson JL, Lee EB, Kuwabara S, Shibuya K, Irwin DJ, Fang L, Van Deerlin VM, Elman L, McCLuskey L, Ludolph AC, Lee VM, Braak H, Trojanowski JQ. TDP-43 pathology and neuron loss in amyotrophic lateral sclerosis spinal cord. Acta Neuropathologica. 128(3): 423-37, 2014

Liu EY, Russ J, Wu K, Neal D, Suh E, McNally AG, Irwin DJ, Van Deerlin VM, Lee EB. C9orf72 hypermethylation protects against repeat expansion associated pathology in ALS/FTD. Acta Neuropathologia. 128(4): 542-41, 2014

Brettschneider J, Del Tredici K, Irwin DJ, Gromssan M, Robinson JL, Toledo JB, Lee EB, Fang L, Van Deerlin VM, Ludolph AC, Lee VM, Braak H, Trojanowski JQ. Sequential distribution of pTDP-43 pathology in behavioral variant frontotemporal dementia (bvFTD). Acta Neuropathologica. 127(3): 423-39, 2014.

Lee EB, Mattson MP. The neuropathology of obesity: insights from human disease. Acta Neuropathologica. 127(1): 3-28, 2014


Wood EM, Falcone D, Suh E, Irwin DJ, Chen-Plotkin AS, Lee EB, Xie S, Van Deerlin VM, Grossman M. Development and validation of pedigree classification for frontotemporal lobar degeneration. JAMA Neurology. 70(11): 1411-7, 2013

Arnold SE, Toledo JB, Appleby DH, Xie SX, Wang LS, Baek Y, Wolk DA, Lee EB, Miller BL, Lee VM, Trojanowski JQ. A comparative survey of the topographical distribution of signature molecular lesions in major neurodegenerative diseases. J Comp Neurol. 521(18): 4339-55, 2013.

Toledo JB, Van Deerlin VM, Lee EB, Suh E, Baek Y, Robinson JL, Xie SS, McBride J, Wood EM, Schuck T, Irwin D, Gross RG, Hurtig H, McCluskey L, Elman L, Karlawish J, Schellenberg G, Chen-Plotkin A, Wolk D, Grossman M, Arnold SE, Shaw LM, Lee VM-Y, Trojanowski JQ. A platform for discovery: The University of Pennsylvania Integrated Neurodegenerative Disease Biobank. Alzheimer's and Dementia. 10(4): 477-87, 2013.

Brettschneider J, Tredicki, KD, Toledo JB, Robinson JL, Irwin DJ, Grossman M, Suh E, Van Deerlin VM, Wood EM, Baek Y, Kwong L, Lee EB, Elman L, McCluskey L, Fang L, Feldengut S, Ludolph AC, Lee VM, Braak H, Trojanowski JQ. Stages of pTDP-43 pathology in amyotrophic lateral sclerosis. Ann Neurol. 74(1): 20-38, 2013.

Lee EB*, Russ J, Jung H, Elman LB, Chahine LM, Kremer D, Miller BL, Coslett HB, Trojanowski JQ, Van Deerlin VM, McCluskey LF. Topography of FUS pathology distinguishes late-onset BIBD from aFTLD-U. Acta Neuropathologica Communications. 1:9, May 2013. *Corresponding author


Yarchoan M, Xie SX, Kling MA, Toledo JB, Wolk DA, Lee EB, Van Deerlin V, Lee VM.-Y., Trojanowski JQ, Arnold SE. Cerebrovascular atherosclerosis correlates with Alzheimer pathology in neurodegenerative dementias. Brain. 135(12): 3749-56, Dec 2012.

Brettschneider J, van Deerlin V, Robinson J, Kwong L, Lee Edward B, Ali YO, Safren N, Monteiro M, Toledo JB, Elman L, McCluskey L, Irwin DJ, Grossman M, Molina L, Lee VMY, Trojanowski JQ.  Pattern of ubiquilin pathology in ALS and FTLD indicates presence of C9ORF72 hexanucleotide expansion.  Acta Neuropathologica. 123(6): 825-39, Jun 2012.

Patel S, Lee EB, Xie SX, Law A, Jackson EM, Arnold SE, Clark CM, Shaw LM, Grady MS, Trojanowski JQ, Hamilton RH. Phosphorylated tau/amyloid beta 1-42 ratio in ventricular cerebrospinal fluid reflects outcome in idiopathic normal pressure hydrocephalus. Fluids Barriers CNS. 9(1): 7, Mar 2012

Wang Sumei, Kim Sungheon, Zhang Yu, Wang Lu, Lee Edward B., Syre Peter, Poptani Harish, Melhem Elias R., Lee John Y.K.: Grading and subtyping of meningiomas using histogram analysis of diffusion tensor imaging. Radiology 262(2): 584-92, Feb 2012.

Lee Edward B and Ahima Rexford S. Alteration of hypothalamic cellular dynamics in obesity. The journal of clinical investigation. 122(1): 22-5, Jan 2012.


Lee Edward B. Obesity, leptin and Alzheimer's disease. Annals of the New York academy of sciences. 1243(1): 15-29, Dec 2011.

Lee Edward B, Lee Virginia M.-Y. and Trojanowski John Q. Gains or losses: molecular mechanisms of TDP43-mediated neurodegeneration. Nature reviews neuroscience 13(1): 38-50, Nov 2011.

Lee Edward B, Warmann Genevieve, Dhir Ravindra and Ahima Rexford S. Metabolic dysfunction associated with adiponectin deficiency enhances kainic acid-induced seizure severity. Journal of neuroscience 31(40):14361-14366, October 2011.

Lee Edward B and Ahima Rexford S.: Central regulation of appetite and satiety behavior. Handbook of Behavior, Diet and Nutrition. Preedy VR (eds.). 2011

Lim Younshin, Kehm Victoria M, Lee Edward B, Soper James H, Li Chi, Trojanowski John Q, Lee Virginia M Y: Alpha-synuclein suppression reverses synaptic and memory defects in a mouse model of dementia with Lewy bodies. Journal of neuroscience 31(27):10076-87, July  2011.

Igaz Lionel M*, Kwong Linda K*, Lee Edward B*, Chen-Plotkin Alice, Swanson Eric, Unger Travis, Malunda Joe, Xu Yan, Winton Matthew J, Trojanowski John Q, Lee Virginia M-Y: Dysregulation of the ALS-associated gene TDP-43 leads to neuronal death and degeneration in mice. The Journal of clinical investigation 121(2): 726-38, Feb 2011. PMCID: PMC3026736   *Co-lead authors


Hamilton Roy, Patel Sunil, Lee Edward B, Jackson Eric M, Lopinto Joanna, Arnold Steven E, Clark Christopher M, Basil Anuj, Shaw Leslie M, Xie Sharon X, Grady M Sean, Trojanowski John Q: Lack of shunt response in suspected idiopathic normal pressure hydrocephalus with Alzheimer disease pathology. Annals of neurology 68(4): 535-40, Oct 2010. PMCID: PMC2964442

Prasad Sashank, Lee Edward B, Woo John H, Alavi Abass, Galetta Steven L: Photo essay. MRI and positron emission tomography findings in Heidenhain variant Creutzfeldt-Jakob disease. Journal of neuro-ophthalmology 30(3): 260-2, Sep 2010. PMCID: PMC2964442

Arnold Steven E, Lee Edward B, Moberg Paul J, Stutzbach Lauren, Kazi Hala, Han Li-Ying, Lee Virginia M Y, Trojanowski John Q: Olfactory epithelium amyloid-beta and paired helical filament-tau pathology in Alzheimer disease. Annals of neurology 67(4): 462-9, Apr 2010. PMCID: PMC2864948

Turkeltaub Peter E, Guzman Miguel A, Lee Edward B, Galetta Steven L: Idiopathic eosinophilic meningoencephalomyelitis following Well syndrome. Neurology 73(23): 2037-9, Dec 2009. PMCID: PMC2790232

Ranalli Nathan J, Huang Jason H, Lee Edward B, Zhang Paul J L, Siegelman Evan S, Zager Eric L: Hemangiomas of the brachial plexus: a case series. Neurosurgery 65(4 Suppl): A181-8, Oct 2009. PMCID: PMC2864948

Kim A K, Lee E B, Bagley L J, Loevner L A: Retained surgical sponges after craniotomies: imaging appearances and complications. AJNR. American journal of neuroradiology 30(6): 1270-2, Jun 2009. PMCID: PMC2790232

Lee Edward B, Tihan Tarik, Scheithauer Bernd W, Zhang Paul J, Gonatas Nicholas K: Thyroid transcription factor 1 expression in sellar tumors: a histogenetic marker? Journal of neuropathology and experimental neurology 68(5): 482-8, May 2009. PMCID: PMC2790232

Ko Melissa W, Turkeltaub Peter E, Lee Edward B, Gonatas Nicholas K, Volpe Nicholas J, Moster Mark L, Galetta Steven L: Primary diffuse leptomeningeal gliomatosis mimicking a chronic inflammatory meningitis. Journal of the neurological sciences 278(1-2): 127-31, Mar 2009. PMCID: PMC2790232

Neumann Manuela, Kwong Linda K, Lee Edward B, Kremmer Elisabeth, Flatley Andrew, Xu Yan, Forman Mark S, Troost Dirk, Kretzschmar Hans A, Trojanowski John Q, Lee Virginia M-Y: Phosphorylation of S409/410 of TDP-43 is a consistent feature in all sporadic and familial forms of TDP-43 proteinopathies. Acta neuropathologica 117(2): 137-49, Feb 2009. PMCID: PMC2693625



Prasad S, Moss H E, Lee E B, Glisson C C, Galetta S L: Clinical reasoning: a 42-year-old man with sequential monocular visual loss. Neurology 71(17): e43-9, Oct 2008. PMCID: PMC2693625

Lee Edward B, Lee Virginia M-Y, Trojanowski John Q, Neumann Manuela: TDP-43 immunoreactivity in anoxic, ischemic and neoplastic lesions of the central nervous system. Acta neuropathologica 115(3): 305-11, Mar 2008. PMCID: PMC2693625

Lee Edward B and Lee Virginia M.-Y.: Biology and molecular neuropathology of ?-amyloid protein. Neurobiology of Alzheimer's Disease, 3rd edition. Dawbarn D and Allen SJ (eds.). 2007.
Prasad Sashank, Ko Melissa W, Lee Edward B, Gonatas Nicholas K, Stern Matthew B, Galetta Steven: Supranuclear vertical gaze abnormalities in sporadic Creutzfeldt-Jakob disease. Journal of the neurological sciences 253(1-2): 69-72, Feb 2007. PMCID: PMC2693625



Lee Edward B, Leng Lewis Z, Zhang Bin, Kwong Linda, Trojanowski John Q, Abel Ted, Lee Virginia M-Y: Targeting amyloid-beta peptide (Abeta) oligomers by passive immunization with a conformation-selective monoclonal antibody improves learning and memory in Abeta precursor protein (APP) transgenic mice. The Journal of biological chemistry 281(7): 4292-9, Feb 2006. PMCID: PMC2693625

Lee Edward B, Leng Lewis Z, Lee Virginia M-Y, Trojanowski John Q: Meningoencephalitis associated with passive immunization of a transgenic murine model of Alzheimer's amyloidosis. FEBS letters 579(12): 2564-8, May 2005. PMCID: PMC2693625

Lazarov Orly, Morfini Gerardo A, Lee Edward B, Farah Mohamed H, Szodorai Anita, DeBoer Scott R, Koliatsos Vassilis E, Kins Stefan, Lee Virginia M-Y, Wong Philip C, Price Donald L, Brady Scott T, Sisodia Sangram S: Axonal transport, amyloid precursor protein, kinesin-1, and the processing apparatus: revisited. The Journal of neuroscience 25(9): 2386-95, Mar 2005.

Zhang Bin, Maiti Arpita, Shively Sharon, Lakhani Fara, McDonald-Jones Gaye, Bruce Jennifer, Lee Edward B, Xie Sharon X, Joyce Sonali, Li Chi, Toleikis Philip M, Lee Virginia M-Y, Trojanowski John Q: Microtubule-binding drugs offset tau sequestration by stabilizing microtubules and reversing fast axonal transport deficits in a tauopathy model. Proceedings of the National Academy of Sciences of the United States of America 102(1): 227-31, Jan 2005. PMCID: PMC544048

Lee Edward B, Zhang Bin, Liu Kangning, Greenbaum Eric A, Doms Robert W, Trojanowski John Q, Lee Virginia M-Y: BACE overexpression alters the subcellular processing of APP and inhibits Abeta deposition in vivo. The Journal of cell biology 168(2): 291-302, Jan 2005. PMCID: PMC2171598



Sung Syaun, Yang Hengxuan, Uryu Kunihiro, Lee Edward B, Zhao Lei, Shineman Diana, Trojanowski John Q, Lee Virginia M-Y, Pratic? Domenico: Modulation of nuclear factor-kappa B activity by indomethacin influences A beta levels but not A beta precursor protein metabolism in a model of Alzheimer's disease. The American journal of pathology 165(6): 2197-206, Dec 2004. PMCID: PMC1618710

Watson Deborah J, Longhi Luca, Lee Edward B, Fulp Carl T, Fujimoto Scott, Royo Nicolas C, Passini Marco A, Trojanowski John Q, Lee Virginia M Y, McIntosh Tracy K, Wolfe John H: Genetically modified NT2N human neuronal cells mediate long-term gene expression as CNS grafts in vivo and improve functional cognitive outcome following experimental traumatic brain injury. Journal of neuropathology and experimental neurology 62(4): 368-80, Apr 2003. PMCID: PMC1618710

Lee Edward B, Skovronsky Daniel M, Abtahian Farhad, Doms Robert W, Lee Virginia M-Y: Secretion and intracellular generation of truncated Abeta in beta-site amyloid-beta precursor protein-cleaving enzyme expressing human neurons. The Journal of biological chemistry 278(7): 4458-66, Feb 2003. PMCID: PMC1618710

Passini Marco A, Lee Edward B, Heuer Gregory G, Wolfe John H: Distribution of a lysosomal enzyme in the adult brain by axonal transport and by cells of the rostral migratory stream. The Journal of neuroscience 22(15): 6437-46, Aug 2002. PMCID: PMC1618710

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