Qing Chen, MD, PhD
Wistar Institute Assistant Professor of Pathology and Laboratory Medicine
Department: Pathology and Laboratory Medicine
Graduate Group Affiliations
Contact information
Memorial Sloan-Kettering Cancer Center
1275 York Avenue, Box 116
New York, NY 10021
1275 York Avenue, Box 116
New York, NY 10021
Office: 646-888-2063
Email:
qichen@wistar.org
qichen@wistar.org
Education:
M.D. (Clinical Medicine)
Capital University of Medical Sciences, 1997.
M.S. (Molecular Neurobiology)
Beijing Institute of Neuroscience, Capital University of Medical Sciences, 2000.
PhD (Immunology)
Roswell Park Cancer Institute, State University of New York at Buffalo, 2006.
Permanent linkM.D. (Clinical Medicine)
Capital University of Medical Sciences, 1997.
M.S. (Molecular Neurobiology)
Beijing Institute of Neuroscience, Capital University of Medical Sciences, 2000.
PhD (Immunology)
Roswell Park Cancer Institute, State University of New York at Buffalo, 2006.
Selected Publications
Valiente M., Obenhauf A., Jin X., Chen Q., Zhang X.H., Lee D., Jamie E., Chaft, J.E., Mark G., Kris, M.G., Huse J.T., Edi, Brogi E., Massague J.: Serpins shield brain metastatic cells from death signals and vascular detachment. Cell 156(5): 1002-1016, Feb 2014.Chen, Q. and Massague', J. : Molecular pathways: VCAM-1 as a potential therapeutic target in metastasis. Clinical Cancer Research 18(20): 5520-5525, Oct 2012 Notes: doi: 10.1158/1078-0432.CCR-11-2904. Epub 2012 Aug 9.
Fisher, D.T., Chen, Q., Skitzki, J.J., Muhitch, J.B., Zhou, L., Appenheimer, M. M., Vardam, T.D., Weis, E.E., Passasanese, J., Wang, W.C., Dewhirst, M., W., Rose-John, S., Repasky, E.E., Baumann, H., Evans, S.S.: IL-6 trans-signaling licenses murine and human tumor microvascular gateways for trafficking of cytotoxic T cells. J. Clin. Invest 121(10): 3846-59, Oct 2011 Notes: doi: 10.1172/JCI44952. Epub 2011 Sep 19.
Chen Q., Zhang, X.H. Massague, J.: VCAM1 mediates survival of breast cancer on arrival in the lungs. Cancer Cell 20(4): 538-49, Oct 2011 Notes: doi: 10.1016/j.ccr.2011.08.025.
Chen, Q., Appenheimer, M.M., Muhitch, J.B. Fisher, D.T., Clancy, K.A., Miencznikowski, J.C., Wang, W.C., Evans, S.S.: Thermal facilitation of lymphocyte trafficking involves temporal induction of intravascular ICAM-1. Microcirculation 16(2): 143-58, Feb 2009 Notes: doi: 10.1080/10739680802353850. Epub 2008 Dec 27.
Evans, S.S., Fisher, D.T., Skitzki, J.J., Chen Q.: Targeted regulation of a lymphocyte-endothelial-interleukin-6 axis by thermal stress. International Journal of Hyperthermia 24(4): 67-68, Feb 2008 Notes: doi: 10.1080/02656730701772498.
Appenheimer, M.M., Girard R.A., Chen, Q., Wang, W.C., Bankert, K.C., Hardison, J., Bain M.D., Ridgley, F., Sarcione, E.J., Buitrago S., Kaspers, B., Robert, J., Baumann, H. and Evans, S. : Conservation of IL-6 trans-signaling mechanisms controlling L-selectin adhesion by fever-range thermal stress. European Journal of Immunology 38(10): 2856-2867, Oct 2007.
Vardam, T.D., Zhou, L., Appenheimer, M.M., Chen, Q., Wang, W.C., Baumann, H., Evans, S.S.: Regulation of a lymphocyte-endothelial-IL-6 trans-signaling axis by fever-range thermal stress: hot spot of immune surveillance. Cytokine 29(1): 84-96, Jul 2007.
Chen Q, Clancy KA, Wang WC, Evans SS: High endothelial venules: master regulators of lymphocyte trafficking and targets of fever-range thermal stress. Endothelial Biomedicine. William Aird (eds.). Cambridge University Press, 2007 Notes: Chapter.
Chen, Q., Fisher D.T., Clancy K.A., Gauguet J.M., Wang W.C., Unger E., Rose-John S., Von Andrian, U.H., and Evans S.S.: Fever-range thermal stress promotes lymphocyte trafficking across high endothelial venules via an interleukin 6 trans-signaling mechanism. Nature Immunology 7(12): 1288-12308, Dec 2006.