Saar I Gill, MD, PhD

faculty photo
Assistant Professor of Medicine at the Hospital of the University of Pennsylvania
Department: Medicine
Graduate Group Affiliations

Contact information
Room 8-101
Smilow Translational Research Center
3400 Civic Center Blvd
Philadelphia, PA 19104
Office: (215) 573-4015
Lab: (215) 573-4015
Education:
MBBS (medicine)
University of Melbourne, 1999.
PhD (immunology)
University of Melbourne, 2011.
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Description of Research Expertise

Tumor Immunology
Chimeric Antigen Receptor T cells
Mouse Models of Human Leukemia
Murine Xenografts
Adoptive Cellular Therapy
Genetic Engineering of T cells
Flow Cytometry

Selected Publications

Ruella M, Klichinsky M, Kenderian SS, Shestova O, Ziober A, Kraft DO, Feldman M, Wasik MA, June CH, Gill S: Overcoming the Immunosuppressive Tumor Microenvironment of Hodgkin Lymphoma Using Chimeric Antigen Receptor T Cells. Cancer Discovery June 2 2017 Notes: doi: 10.1158/2159-8290.

Tasian Sarah K, Kenderian Saad S, Shen Feng, Ruella Marco, Shestova Olga, Kozlowski Miroslaw, Li Yong, Schrank-Hacker April, Morrissette Jennifer J D, Carroll Martin, June Carl H, Grupp Stephan A, Gill Saar: Optimized depletion of chimeric antigen receptor T cells in murine xenograft models of human acute myeloid leukemia. Blood 129(17): 2395-2407, Apr 2017.

Glisovic-Aplenc Tina, Gill Saar, Spruce Lynn A, Smith Ian R, Fazelinia Hossein, Shestova Olga, Ding Hua, Tasian Sarah K, Aplenc Richard, Seeholzer Steven H: Improved surfaceome coverage with a label-free nonaffinity-purified workflow. Proteomics 17(7), Apr 2017 Notes: doi: 10.1002/pmic.201600344.

Gill Saar: Monkey business: Repurposing a protein from the simian immunodeficiency virus to enhance cytotoxic chemotherapy. Science translational medicine 9(375), Feb 2017.

Gill Saar: CAR T cells engage in anticancer martial arts. Science translational medicine 9(373), Jan 2017.

Gill Saar: Chimeric antigen receptor T cell therapy in AML: How close are we? Best practice & research. Clinical haematology 29(4): 329-333, Dec 2016.

Ruella Marco, Barrett David M, Kenderian Saad S, Shestova Olga, Hofmann Ted J, Perazzelli Jessica, Klichinsky Michael, Aikawa Vania, Nazimuddin Farzana, Kozlowski Miroslaw, Scholler John, Lacey Simon F, Melenhorst Jan J, Morrissette Jennifer J D, Christian David A, Hunter Christopher A, Kalos Michael, Porter David L, June Carl H, Grupp Stephan A, Gill Saar: Dual CD19 and CD123 targeting prevents antigen-loss relapses after CD19-directed immunotherapies. The Journal of clinical investigation 126(10): 3814-3826, Oct 2016.

Kenderian Saad S, Porter David L, Gill Saar: Chimeric Antigen Receptor T Cells and Hematopoietic Cell Transplantation: How Not to Put the CART Before the Horse. Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 23(2): 235-246, Sep 2016.

Gill Saar: Planes, Trains, and Automobiles: Perspectives on CAR T Cells and Other Cellular Therapies for Hematologic Malignancies. Current hematologic malignancy reports 11(4): 318-25, Aug 2016.

Kumar Anita J, Vassilev Pavel, Loren Alison W, Luger Selina M, Reshef Ran, Gill Saar, Smith Jacqueline, Goldstein Steven C, Hexner Elizabeth, Stadtmauer Edward A, Porter David, Frey Noelle V: Time to unrelated donor leukocyte infusion is longer, but incidence of GVHD and overall survival are similar for recipients of unrelated DLI compared to matched sibling DLI. American journal of hematology 91(4): 426-9, Jun 2016.

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Last updated: 10/12/2017
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