Airway smooth muscle, matrix, VEGF, signal transduction
Asthma, COPD, COPD clinical trials
Bloomer JC, Nash M, Webb A, Miller BE, Lazaar A, Beaumont C, Guiney WJ: Assessment of potential drug interactions by characterisation of human drug metabolism pathways using non-invasive bile sampling. British Journal of Clinical Pharmacology 75: 488-496, 2012.
Esther CR, Lazaar AL, Bordonali E, Qaqish B, Boucher RC: Elevated airway purines in chronic obstructive pulmonary disease. Chest 140: 954-960, 2011.
Lazaar AL, Sweeney LE, MacDonald AJ, Alexis NE, Chen C, Deans A, Tal-Singer R: SB-656933, a novel CXCR2 selective antagonist, inhibits ex-vivo neutrophil activation and ozone-induced airway inflammation in humans. British Journal of Clinical Pharmacology 72: 282-293, 2011.
Singh D, Petavy F, Macdonald AJ, Lazaar A and O`Connor BJ: The inhaled phosphodiesterase 4 inhibitor GSK256066 inhibits allergen challenge responses in asthma. Respiratory Research 11: 26, 2010.
Kim JH, Van Biesen C, Lazaar AL: VEGF alters tracheal ring force generation in a rho-dependent manner. Am J Respir Crit Care Med 169: A445, 2004.
Kazi AS, Lotfi S, Krymskaya VP, Lazaar AL. : Vascular endothelial growth factor (VEGF) up regulates fibronectin and matrix metalloproteinase-2 (MMP-2) secretion by human airway smooth muscle cells. Am J Respir Crit Care Med 167: A689, 2003.
Goncharova EA, Goncharov DA, Panettieri RA, Lazaar AL, Krymskaya VP. : VEGF stimulates proliferation and migration of LAM-derived cells. Am J Respir Crit Care Med 167: A953, 2003.
Kim JH, Ammit AJ, Puré E, Lazaar AL. : Hyaluronan activates NF-kB and induces IL-6 by human airway smooth muscle cells. Am J Respir Crit Care Med 167: A690, 2003.
Lazaar AL, Panettieri RA: Airway Smooth Muscle: An Immunomodulatory Cell? Therapeutic Targets in Airway Inflammation. Eissa NT, Huston DP (eds.). Marcel Dekker, Inc., New York 177: 767-780, 2003.
Lazaar, A L. Albelda, S M. Pilewski, J M. Brennan, B. Pure, E. Panettieri, R A Jr.: T lymphocytes adhere to airway smooth muscle cells via integrins and CD44 and induce smooth muscle cell DNA synthesis. Journal of Experimental Medicine 180(3): 807-16, Sep 1 1994.
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Last updated: 05/28/2015
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