Paul F. Harron Jr. Lung Center

Paul F. Harron Jr. Lung Center Faculty

faculty photo

Reynold A. Panettieri, Jr., MD

Robert L. Mayock and David A. Cooper Professor of Pulmonary Medicine
Director, Comprehensive Asthma Program, University of Pennsylvania Health System
Chief, Asthma Section, Pulmonary, Allergy & Critical Care Division, University of Pennsylvania
Director, Airways Biology Initiative, University of Pennsylvania
Associate Program Director, General Clinical Research Program, University of Pennsylvania
Director, Integrative Health Sciences Facilty Core, Center of Excellence in Environmental Toxicology, University of Pennsylvania
Deputy Director, Center of Excellence in Environmental Toxicology, University of Pennsylvania
Department: Medicine

Contact information
University of Pennsylvania
125 South 31st Street
TRL Suite 1200
Philadelphia, PA 19104-3413
Office: (215) 573-9860
Fax: (215) 746-1224
Lab: (215) 746-2759
B.S. (Biology)
St. Joseph's University, Philadelphia, PA, 1979.
M.D. (Medicine)
University of Pennsylvania, 1983.
M.A. (Honorary)
University of Pennsylvania, 1998.
Post-Graduate Training
Intern in Medicine, Hospital of the University of Pennsylvania , 1983-1984.
Resident in Medicine , Hospital of the University of Pennsylvania, 1984-1986.
Fellowship, Pulmonary Diseases, Hospital of the University of Pennsylvania, 1986-1989.
Research Fellowship (Supervisors: Drs. Alan Kelly and Neal Rubinstein) , University of Pennsylvania, 1987-1989.
Research Fellowship (Supervisor: Dr. Peter Nowell) , University of Pennsylvania, 1988-1989.
Internal Medicine, 1986.
Pulmonary Medicine, 1988.
Critical Care Medicine, 1992.
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> Perelman School of Medicine   > Faculty   > Details

Description of Research Expertise

Smooth muscle biology, airway remodeling, respiratory pharmacology and physiology

Description of Clinical Expertise

Asthma, chronic obstructive pulmonary disease, irreversible airway obstruction

Selected Publications

Panettieri Reynold A: Bronchial Thermoplasty: Targeting Structural Cells in Severe Persistent Asthma. Annals of the American Thoracic Society 12(11): 1593-1594, Nov 2015.

Carr Richard, Koziol-White Cynthia, Zhang Jie, Lam Hong, Ahn Steven S, Tall Gregory G, Panettieri Reynold A, Benovic Jeffrey L: Interdicting Gq Activation in Airway Disease by Receptor-Dependent and Receptor-Independent Mechanisms. Molecular pharmacology Page: Epub ahead of print, October 2015.

Panettieri Reynold A: Bronchodilators, receptors and cross-talk: together is better? Postgraduate medicine 127(7): 771-780, September 2015.

Kohli Puja, Pinto-Plata Victor, Divo Miguel, Malhotra Atul, Harris R Scott, Lazaar Aili, Flynn Aiden, Tal-Singer Ruth, Panettieri Reynold A, Celli Bartolome: Functional Capacity, Health Status, and Inflammatory Biomarker Profile in a Cohort of Patients With Chronic Obstructive Pulmonary Disease. Journal of cardiopulmonary rehabilitation and prevention 35(5): 348-55, September-October 2015.

Sun Yan, Jain Deepika, Koziol-White Cynthia J, Genoyer Emmanuelle, Gilbert Micah, Tapia Karla, Panettieri Reynold A, Hodinka Richard L, López Carolina B: Immunostimulatory Defective Viral Genomes from Respiratory Syncytial Virus Promote a Strong Innate Antiviral Response during Infection in Mice and Humans. PLoS pathogens 11(9): e1005122, September 2015.

Liao Guoning, Panettieri Reynold A, Tang Dale D: MicroRNA-203 negatively regulates c-Abl, ERK1/2 phosphorylation, and proliferation in smooth muscle cells. Physiological reports 3(9): e12541, September 2015.

Panettieri, R.A., Jr.: New details on family poisoned by pesticide. CNN, September 2015 Notes: Interviewed by CNN Correspondent Sara Ganim Regarding Family Exposed to Methyl Bromide, June 2015

Panettieri, R.A., Jr.: Radio Interview Re: Cardiovascular hospitalizations in hydrofracking areas. WPEL Radio, Montrose, PA September 2015 Notes: Larry Souder, WPEL Radio, Montrose, PA, interviewed Dr. Panettieri on 9/2/15; the interviewed aired on 9/26/15.

Panettieri, R.A., Jr., Brightling, C., Sjobring, U., Peterffy, A., Tornling, G., Daoud, S.Z., Ranade, K., Hollis, S., Colice, G.: STRATOS 1 and 2: considerations in clinical trial design for a fully human monoclonal antibody in severe asthma. Clinical Investigation (London) 5(8): 701-711, August 2015.

Jemielita Thomas, Gerton George L, Neidell Matthew, Chillrud Steven, Yan Beizhan, Stute Martin, Howarth Marilyn, Saberi Pouné, Fausti Nicholas, Penning Trevor M, Roy Jason, Propert Kathleen J, Panettieri Reynold A: Correction: Unconventional Gas and Oil Drilling Is Associated with Increased Hospital Utilization Rates. PloS One 10(8): e0137371, August 2015 Notes: Data availability statement corrected.

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Last updated: 11/27/2015
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