Penn Lung Center

Faculty & Staff

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Reynold A. Panettieri, Jr., MD

Robert L. Mayock and David A. Cooper Professor of Pulmonary Medicine
Director, Comprehensive Asthma Program, University of Pennsylvania Health System
Chief, Asthma Section, Pulmonary, Allergy & Critical Care Division, University of Pennsylvania
Director, Airways Biology Initiative, University of Pennsylvania
Associate Program Director, General Clinical Research Program, University of Pennsylvania
Director, Integrative Health Sciences Facilty Core, Center of Excellence in Environmental Toxicology, University of Pennsylvania
Deputy Director, Center of Excellence in Environmental Toxicology, University of Pennsylvania
Department: Medicine

Contact information
University of Pennsylvania
125 South 31st Street
TRL Suite 1200
Philadelphia, PA 19104-3413
Office: (215) 573-9860
Fax: (215) 746-1224
Lab: (215) 746-2759
Graduate Group Affiliations
Education:
B.S. (Biology)
St. Joseph's University, Philadelphia, PA, 1979.
M.D. (Medicine)
University of Pennsylvania, 1983.
M.A. (Honorary)
University of Pennsylvania, 1998.
Post-Graduate Training
Intern in Medicine, Hospital of the University of Pennsylvania , 1983-1984.
Resident in Medicine , Hospital of the University of Pennsylvania, 1984-1986.
Fellowship, Pulmonary Diseases, Hospital of the University of Pennsylvania, 1986-1989.
Research Fellowship (Supervisors: Drs. Alan Kelly and Neal Rubinstein) , University of Pennsylvania, 1987-1989.
Research Fellowship (Supervisor: Dr. Peter Nowell) , University of Pennsylvania, 1988-1989.
Certifications
Internal Medicine, 1986.
Pulmonary Medicine, 1988.
Critical Care Medicine, 1992.
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Description of Research Expertise

Smooth muscle biology, airway remodeling, respiratory pharmacology and physiology

Description of Clinical Expertise

Asthma, chronic obstructive pulmonary disease, irreversible airway obstruction

Selected Publications

Robinett Kathryn S, Koziol-White Cynthia J, Akoluk Arda, An Steven S, Panettieri Jr Reynold A, Liggett Stephen B: Bitter taste receptor function in asthmatic and nonasthmatic human airway smooth muscle cells. American journal of respiratory cell and molecular biology 50(4): 678-683, April 2014.

Balenga Nariman A, Jester William, Jiang Meiqi, Panettieri Jr Reynold A, Druey Kirk M: Loss of regulator of G protein signaling 5 promotes airway hyperresponsiveness in the absence of allergic inflammation. The Journal of allergy and clinical immunology Page: Epub ahead of print, Mar 2014.

Fitzgerald Robert, Desantiago Breann, Lee Danielle Y, Yang Guangdong, Kim Jae Yeon, Brian Foster D, Chan-Li Yee, Horton Maureen R, Panettieri Reynold A, Wang Rui, An Steven S: H2S relaxes isolated human airway smooth muscle cells via the sarcolemmal KATP channel. Biochemical and biophysical research communications 446(1): 393-398, Mar 2014.

Hu Ruoxi, Pan Wenchi, Fedulov Alexey V, Jester William, Jones Matthew R, Weiss Scott T, Panettieri Reynold A, Tantisira Kelan, Lu Quan: MicroRNA-10a controls airway smooth muscle cell proliferation via direct targeting of the PI3 kinase pathway. FASEB journal : official publication of the Federation of American Societies for Experimental Biology Page: Epub ahead of print, Feb 2014.

Deshpande Deepak A, Yan Huandong, Kong Kok-Choi, Tiegs Brian C, Morgan Sarah J, Pera Tonio, Panettieri Reynold A, Eckhart Andrea D, Penn Raymond B: Exploiting functional domains of GRK2/3 to alter the competitive balance of pro- and anticontractile signaling in airway smooth muscle. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 28(2): 956-65, Feb 2014.

Kim Won-Keun, Jain Deepika, Sánchez Melissa D, Koziol-White Cynthia J, Matthews Krystal, Ge Moyar Q, Haczku Angela, Panettieri Reynold A, Frieman Matthew B, López Carolina B: Deficiency of Melanoma Differentiation-associated Protein 5 Results in Exacerbated Chronic Postviral Lung Inflammation. American journal of respiratory and critical care medicine 189(4): 437-48, Feb 2014.

Banerjee, A., Panettieri, R.A., Jr.: Acute respiratory failure due to asthma, Chapter 75. The Intensive Care Unit Manual, 2nd Edition. Lanken, P.N., Manaker, S., Kohl, B.A., Hanson, C.W., III, (Eds.) (eds.). Elsevier Saunders, Philadelphia, PA, Page: 709-714, 2014 Notes: ISBN 978-1-4160-2455-2.

Damera G, Panettieri RA Jr: Irreversible airway obstruction in asthma: what we lose, we lose early. Allergy & Asthma Proceedings. OceanSide Publications, 35: 111-118, 2014.

Panettieri R A Jr: Reducing readmissions in COPD Physician’s Weekly 30(38): http://www.physweekly.com/copd-reducing-readmissions, October 2013.

Panettieri R A Jr: A look at recidivism in COPD management. Physician’s Weekly 30(33): http://www.physweekly.com/copd-recidivism, September 2013.

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Last updated: 04/10/2014
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