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Reynold A. Panettieri, Jr., MD

Emeritus Professor of Medicine
Department: Medicine

Contact information
University of Pennsylvania
125 South 31st Street
TRL Suite 1200
Philadelphia, PA 19104-3413
Office: (215) 573-9860
Fax: (215) 746-1224
Lab: (215) 746-2759
B.S. (Biology)
St. Joseph's University, Philadelphia, PA, 1979.
M.D. (Medicine)
University of Pennsylvania, 1983.
M.A. (Honorary)
University of Pennsylvania, 1998.
Post-Graduate Training
Intern in Medicine, Hospital of the University of Pennsylvania , 1983-1984.
Resident in Medicine , Hospital of the University of Pennsylvania, 1984-1986.
Fellowship, Pulmonary Diseases, Hospital of the University of Pennsylvania, 1986-1989.
Research Fellowship (Supervisors: Drs. Alan Kelly and Neal Rubinstein) , University of Pennsylvania, 1987-1989.
Research Fellowship (Supervisor: Dr. Peter Nowell) , University of Pennsylvania, 1988-1989.
Internal Medicine, 1986.
Pulmonary Medicine, 1988.
Critical Care Medicine, 1992.
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Description of Research Expertise

Smooth muscle biology, airway remodeling, respiratory pharmacology and physiology

Description of Clinical Expertise

Asthma, chronic obstructive pulmonary disease, irreversible airway obstruction

Selected Publications

Carr Richard, Koziol-White Cynthia, Zhang Jie, Lam Hong, An Steven S, Tall Gregory G, Panettieri Reynold A, Benovic Jeffrey L: Interdicting Gq Activation in Airway Disease by Receptor-Dependent and Receptor-Independent Mechanisms. Molecular pharmacology 89: 94-104, January 2016.

McGeachie Michael J, Wu Ann C, Tse Sze Man, Clemmer George L, Sordillo Joanne, Himes Blanca E, Lasky-Su Jessica, Chase Robert P, Martinez Fernando D, Weeke Peter, Shaffer Christian M, Xu Hua, Denny Josh C, Roden Dan M, Panettieri Reynold A, Raby Benjamin A, Weiss Scott T, Tantisira Kelan G: CTNNA3 and SEMA3D: Promising loci for asthma exacerbation identified through multiple genome-wide association studies. The Journal of allergy and clinical immunology 136(6): 1503-1510, December 2015.

Panettieri Reynold A: Bronchial Thermoplasty: Targeting Structural Cells in Severe Persistent Asthma. Annals of the American Thoracic Society 12(11): 1593-1594, Nov 2015.

Panettieri Reynold A: Bronchodilators, receptors and cross-talk: together is better? Postgraduate medicine 127(7): 771-780, September 2015.

Kohli Puja, Pinto-Plata Victor, Divo Miguel, Malhotra Atul, Harris R Scott, Lazaar Aili, Flynn Aiden, Tal-Singer Ruth, Panettieri Reynold A, Celli Bartolome: Functional Capacity, Health Status, and Inflammatory Biomarker Profile in a Cohort of Patients With Chronic Obstructive Pulmonary Disease. Journal of cardiopulmonary rehabilitation and prevention 35(5): 348-55, September-October 2015.

Sun Yan, Jain Deepika, Koziol-White Cynthia J, Genoyer Emmanuelle, Gilbert Micah, Tapia Karla, Panettieri Reynold A, Hodinka Richard L, López Carolina B: Immunostimulatory Defective Viral Genomes from Respiratory Syncytial Virus Promote a Strong Innate Antiviral Response during Infection in Mice and Humans. PLoS pathogens 11(9): e1005122, September 2015.

Liao Guoning, Panettieri Reynold A, Tang Dale D: MicroRNA-203 negatively regulates c-Abl, ERK1/2 phosphorylation, and proliferation in smooth muscle cells. Physiological reports 3(9): e12541, September 2015.

Panettieri, R.A., Jr.: New details on family poisoned by pesticide. CNN, September 2015 Notes: Interviewed by CNN Correspondent Sara Ganim Regarding Family Exposed to Methyl Bromide, June 2015

Panettieri, R.A., Jr.: Radio Interview Re: Cardiovascular hospitalizations in hydrofracking areas. WPEL Radio, Montrose, PA September 2015 Notes: Larry Souder, WPEL Radio, Montrose, PA, interviewed Dr. Panettieri on 9/2/15; the interviewed aired on 9/26/15.

Panettieri, R.A., Jr., Brightling, C., Sjobring, U., Peterffy, A., Tornling, G., Daoud, S.Z., Ranade, K., Hollis, S., Colice, G.: STRATOS 1 and 2: considerations in clinical trial design for a fully human monoclonal antibody in severe asthma. Clinical Investigation (London) 5(8): 701-711, August 2015.

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Last updated: 12/31/2015
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