Penn Lung Center

Faculty & Staff

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Joshua M. Diamond, MD, MSCE

Assistant Professor of Medicine at the Hospital of the University of Pennsylvania
Associate Medical Director, Lung Transplantation, University of Pennsylvania
Department: Medicine

Contact information
Hospital of the University of Pennsylvania
3400 Spruce St.
821 West Gates
Philadelphia, PA 19104
Office: 215-615-5030
Education:
B.S. (Microbiology and Immunology)
University of Rochester, 2000.
M.D. (Medicine)
University of Rochester School of Medicine and Dentistry, 2004.
M.S.C.E. (Clinical Epidemiology)
University of Pennsylvania, 2011.
Post-Graduate Training
Intern in Internal Medicine, Hospital of the University of Pennsylvania, 2004-2005.
Resident in Internal Medicine, Hospital of the University of Pennsylvania, 2005-2007.
Chief Resident in Internal Medicine, Hospital of the University of Pennsylvania, 2007-2008.
Fellow in Pulmonary and Critical Care Medicine, Hospital of the University of Pennsylvania, 2008-2011.
Certifications
American Board of Internal Medicine - Internal Medicine, 2007.
American Board of Internal Medicine - Pulmonary Medicine, 2010.
American Board of Internal Medicine - Critical Care, 2012.
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Description of Research Expertise

My research is focused on translational studies of clinical and genetic risk factors for Primary Graft Dysfunction (PGD) and chronic rejection after lung transplantation. In addition to increased perioperative mortality, patients recovering from severe PGD have decreased quality of life and an increase risk of chronic rejection, the leading obstacle to long term survival after lung transplantation. Therefore, studies of the mechanisms of PGD and BOS will have a significant impact on the field of lung transplantation and may lead to therapies that improve the overall survival of lung transplant recipients. My current primary research interest is evaluating the role of innate immune activation in the development of post-lung transplant PGD and chronic rejection. I am also actively involved in integrating data on differential innate immune activation with the expanding body of knowledge on microbial colonization and infection of the lower respiratory tract as part of our evaluation of the microbiome of lung transplant recipients

Description of Clinical Expertise

My clinical practice is focused on Advanced Lung Disease and Lung Transplantation. My outpatient practice is at the Penn Lung Center and is predominantly composed of patients before and after lung transplantation. I also have a significant role in Critical Care Medicine, with a primary practice in the Medical Intensive Care Unit at the Hospital of the University of Pennsylvania. Additionally, my practice includes attending on the Procedure and Rapid Response service at the Hospital of the University of Pennsylvania, as well as at the Long Term Acute Care Hospital, at Good Shepard Penn Partners.

Selected Publications

Eberlein Michael, Reed Robert M, Bolukbas Servet, Diamond Joshua M, Wille Keith M, Orens Jonathan B, Brower Roy G, Christie Jason D: Lung size mismatch and primary graft dysfunction after bilateral lung transplantation. The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 34(2): 233-40, Feb 2015.

Young J C, Chehoud C, Bittinger K, Bailey A, Diamond J M, Cantu E, Haas A R, Abbas A, Frye L, Christie J D, Bushman F D, Collman R G: Viral metagenomics reveal blooms of anelloviruses in the respiratory tract of lung transplant recipients. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 15(1): 200-9, Jan 2015.

Diamond Joshua M, Mikkelsen Mark E: From research to clinical practice. Cognitive trajectory after lung transplantation. Annals of the American Thoracic Society 11(10): 1604-5, Dec 2014.

Singer Jonathan P, Peterson Eric R, Snyder Mark E, Katz Patricia P, Golden Jeffrey A, D'Ovidio Frank, Bacchetta Matthew, Sonett Joshua R, Kukreja Jasleen, Shah Lori, Robbins Hilary, Van Horn Kristin, Shah Rupal J, Diamond Joshua M, Wickersham Nancy, Sun Li, Hays Steven, Arcasoy Selim M, Palmer Scott M, Ware Lorraine B, Christie Jason D, Lederer David J: Body composition and mortality after adult lung transplantation in the United States. American journal of respiratory and critical care medicine 190(9): 1012-21, Nov 2014.

Bittinger Kyle, Charlson Emily S, Loy Elizabeth, Shirley David J, Haas Andrew R, Laughlin Alice, Yi Yanjie, Wu Gary D, Lewis James D, Frank Ian, Cantu Edward, Diamond Joshua M, Christie Jason D, Collman Ronald G, Bushman Frederic D: Improved characterization of medically relevant fungi in the human respiratory tract using next-generation sequencing. Genome biology 15(10): 487, Oct 2014.

Cantu Edward, Shah Rupal J, Lin Wei, Daye Zhongyin J, Diamond Joshua M, Suzuki Yoshikazu, Ellis John H, Borders Catherine F, Andah Gerald A, Beduhn Ben, Meyer Nuala J, Ruschefski Melanie, Aplenc Richard, Feng Rui, Christie Jason D: Oxidant stress regulatory genetic variation in recipients and donors contributes to risk of primary graft dysfunction after lung transplantation. The Journal of thoracic and cardiovascular surgery Sep 2014.

Shah Rupal J, Emtiazjoo Amir M, Diamond Joshua M, Smith Patricia A, Roe David W, Wille Keith M, Orens Jonathan B, Ware Lorraine B, Weinacker Ann, Lama Vibha N, Bhorade Sangeeta M, Palmer Scott M, Crespo Maria, Lederer David J, Cantu Edward, Eckert George J, Christie Jason D, Wilkes David S: Plasma complement levels are associated with primary graft dysfunction and mortality after lung transplantation. American journal of respiratory and critical care medicine 189(12): 1564-7, Jun 2014.

Diamond Joshua M, Ahya Vivek N: Mechanical ventilation after lung transplantation. It's time for a trial. Annals of the American Thoracic Society 11(4): 598-9, May 2014.

Cohen DG, Christie JD, Anderson BJ, Diamond JM, Judy RP, Shah RJ, Cantu E, Bellamy SL, Blumenthal NP, Demissie E, Hopkins RO, Mikkelsen ME: Cognitive function, mental health, and health-related quality of life after lung transplantation. Annals of the American Thoracic Society 11(4): 522-30, May 2014.

Suzuki Y, Tiwari JL, Plumenthal NP, Lee J, Diamond JM, Carney K, Borders C, Strain J, Alburger GW, Jackson D, Timar J, Berg J, Hasz RD, Halpern SD, Cantu E: Should We Reconsider Lung Transplantation Through Uncontrolled Donation After Circulatory Death? American Journal of Transplantation 14(4): 966-71, April 2014.

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Last updated: 02/24/2015
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