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Joshua M. Diamond, MD, MSCE

Assistant Professor of Medicine at the Hospital of the University of Pennsylvania
Associate Medical Director, Lung Transplantation, University of Pennsylvania
Director Clinical Research Track, University of Pennsylvania - Pulmonary Critical Care Fellowship training program
HUP Regional UNOS Representative, United Network for Organ Sharing
Department: Medicine

Contact information
Hospital of the University of Pennsylvania
3400 Spruce St.
821 West Gates
Philadelphia, PA 19104
Office: 215-615-5030
B.S. (Microbiology and Immunology)
University of Rochester, 2000.
M.D. (Medicine)
University of Rochester School of Medicine and Dentistry, 2004.
M.S.C.E. (Clinical Epidemiology)
University of Pennsylvania, 2011.
Post-Graduate Training
Intern in Internal Medicine, Hospital of the University of Pennsylvania, 2004-2005.
Resident in Internal Medicine, Hospital of the University of Pennsylvania, 2005-2007.
Chief Resident in Internal Medicine, Hospital of the University of Pennsylvania, 2007-2008.
Fellow in Pulmonary and Critical Care Medicine, Hospital of the University of Pennsylvania, 2008-2011.
American Board of Internal Medicine - Internal Medicine, 2007.
American Board of Internal Medicine - Pulmonary Medicine, 2010.
American Board of Internal Medicine - Critical Care, 2012.
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Description of Research Expertise

My research is focused on translational studies of clinical and genetic risk factors for Primary Graft Dysfunction (PGD) and chronic rejection after lung transplantation. In addition to increased perioperative mortality, patients recovering from severe PGD have decreased quality of life and an increase risk of chronic rejection, the leading obstacle to long term survival after lung transplantation. Therefore, studies of the mechanisms of PGD and BOS will have a significant impact on the field of lung transplantation and may lead to therapies that improve the overall survival of lung transplant recipients. My current primary research interest is evaluating the role of innate immune activation in the development of post-lung transplant PGD and chronic rejection. I am also actively involved in integrating data on differential innate immune activation with the expanding body of knowledge on microbial colonization and infection of the lower respiratory tract as part of our evaluation of the microbiome of lung transplant recipients

Description of Clinical Expertise

My clinical practice is focused on Advanced Lung Disease and Lung Transplantation. My outpatient practice is at the Penn Lung Center and is predominantly composed of patients before and after lung transplantation. I also have a significant role in Critical Care Medicine, with a primary practice in the Medical Intensive Care Unit at the Hospital of the University of Pennsylvania. Additionally, my practice includes attending on the Procedure and Rapid Response service at the Hospital of the University of Pennsylvania, as well as at the Long Term Acute Care Hospital, at Good Shepard Penn Partners.

Selected Publications

Vallabhajosyula Prashanth, Korutla Laxminarayana, Habertheuer Andreas, Reddy Sanjana, Schaufler Christian, Lasky Jared, Diamond Joshua, Cantu Edward: Ex Vivo Lung Perfusion Model to Study Pulmonary Tissue Extracellular Microvesicle Profiles. The Annals of thoracic surgery 103(6), Jun 2017.

Abbas A A, Diamond J M, Chehoud C, Chang B, Kotzin J J, Young J C, Imai I, Haas A R, Cantu E, Lederer D J, Meyer K, Milewski R K, Olthoff K M, Shaked A, Christie J D, Bushman F D, Collman R G: The Perioperative Lung Transplant Virome: Torque Teno Viruses are Elevated in Donor Lungs and Show Divergent Dynamics In Primary Graft Dysfunction. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 17(5): 1313-24, May 2017.

Borders Catherine F, Suzuki Yoshikazu, Lasky Jared, Schaufler Christian, Mallem Djamila, Lee James, Carney Kevin, Bellamy Scarlett L, Bermudez Christian A, Localio A Russell, Christie Jason D, Diamond Joshua M, Cantu Edward: Massive donor transfusion potentially increases recipient mortality after lung transplantation. The Journal of thoracic and cardiovascular surgery 153(5): 1197-1203.e2, May 2017.

T.I. Carter, Y. Suzuki, J. Lasky, C. Schaufler, B. Lim, D. Mallem, C.A. Bermudez, J.M. Diamond, J.D. Christie, X. Yu, R. Feng, E. Cantu: An In Situ Donor Derived Panel of Innate Immune Transcripts Predicts Primary Graft Dysfunction in Lung Transplant Recipients. The Journal of Heart and Lung Transplantation 36(4): S145-146, April 2017.

Baldwin Matthew R, Singer Jonathan P, Huang Debbie, Sell Jessica, Gonzalez Wendy C, Pollack Lauren, Maurer Mathew S, D'Ovidio Frank F, Bacchetta Matthew, Sonett Joshua R, Arcasoy Selim M, Shah Lori, Robbins Hilary, Hays Steven R, Kukreja Jasleen, Greenland John R, Shah Rupal J, Leard Lorriana, Morrell Matthew, Gries Cynthia, Katz Patricia P, Christie Jason D, Diamond Joshua M, Lederer David J: Refining Low Physical Activity Measurement Improves Frailty Assessment in Advanced Lung Disease and Survivors of Critical Illness. Annals of the American Thoracic Society Apr 2017.

C.A. Bermudez, M.R. Molina, A.M. Thomasson, E. Blumberg, J. Lee, L. Gardo, V. Ahya, N. Blumenthal, E. Cantu, J.D. Christie, A. Courtwright, J. Diamond, J. Golato, D. Hadjiliadis, E.J. Hobson, N. Patel, M. Porteous, M. Crespo: Lung Transplant Experience with Public Health Services Increased Risk Donors: Recipient Outcomes and Incidence of Transmission and Conversion. The Journal of Heart and Lung Transplantation 36(4): S52, April 2017.

B. Lim, J. Lasky, C. Schaufler, Y. Suzuki, D. Mallem, M. Molina, C. A. Bermudez, J. M. Diamond, J. D. Christie, E. Cantu.: Lung Allocation Score Implementation Narrowed Racial/Ethnic Disparities in Adult Lung Transplantation Outcomes. The Journal of Heart and Lung Transplantation 36(4): S17, April 2017.

A. Courtwright, D. Zaleski, V. Ahya, C. Bermudez, N. Blumenthal, E. Cantu, J. Christie, T. Claridge, M. Crespo, J. Golato, D. Hadjiliadis, E. Hobson, J. Lee, M. Molina, N. Patel, M. Porteous, J. Diamond: Causes and Preventability of Unplanned Rehospitalization Following Lung Transplantation. The Journal of Heart and Lung Transplantation 36(4), April 2017.

C. Schaufler, J. Lasky, B. Lim, Y. Suzuki, D. Mallem, M. Oyster, D.J. Lederer, K. Meyer, C.A. Bermudez, J. Tobias, V.M. Van Deerlin, K. Olthoff, A. Shaked, J.M. Diamond, E. Cantu, J.D. Christie : Gene Set Enrichment Analysis Identifies a Potential Link Between Smoking and Upregulation of Olfactory Receptor and Cytokine Enrichment Pathways. The Journal of Heart and Lung Transplantation 36(4): S417, April 2017.

Narayan Vivek, Deshpande Charuhas, Bermudez Christian A, Golato Jaclyn M, Lee James C, Diamond Joshua, Vaughn David J: Bilateral Lung Transplantation for Bleomycin-Associated Lung Injury. The oncologist Mar 2017.

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Last updated: 07/25/2017
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