Perelman School of Medicine at the University of Pennsylvania

McKay Orthopaedic Research Laboratory


Eiki Koyama

faculty photo
Research Associate Professor of Orthopaedic Surgery
Department: Orthopaedic Surgery

Contact information
The Children's Hospital of Philadelphia
Translational Research Program in Pediatric Orthopaedics
Division of Orthopaedic Surgery
Department of Surgery
3615 Civic Center Boulevard
Abramson Research Center 910B
Philadelphia, PA 19104
Office: 267-425-2074
Fax: 267-426-2215
Matsumoto Dental University, 1985.
PhD (Developmental Biology)
Okayama University, 1992.
Permanent link
> Perelman School of Medicine   > Faculty   > Details

Selected Publications

Laurita Jason, Koyama Eiki, Chin Bianca, Taylor Jesse A, Lakin Gregory E, Hankenson Kurt D, Bartlett Scott P, Nah Hyun-Duck: The Muenke syndrome mutation (FgfR3P244R) causes cranial base shortening associated with growth plate dysfunction and premature perichondrial ossification in murine basicranial synchondroses. Developmental dynamics : an official publication of the American Association of Anatomists 240(11): 2584-96, Nov 2011.

Zhang Xianrong, Siclari Valerie A, Lan Shenghui, Zhu Ji, Koyama Eiki, Dupuis Holly L, Enomoto-Iwamoto Motomi, Beier Frank, Qin Ling: The critical role of the epidermal growth factor receptor in endochondral ossification. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 26(11): 2622-33, Nov 2011.

Kinumatsu T, Shibukawa Y, Yasuda T, Nagayama M, Yamada S, Serra R, Pacifici M, Koyama E: TMJ development and growth require primary cilia function. Journal of dental research 90(8): 988-94, Aug 2011.

Zak Beverly M, Schuksz Manuela, Koyama Eiki, Mundy Christina, Wells Dan E, Yamaguchi Yu, Pacifici Maurizio, Esko Jeffrey D: Compound heterozygous loss of Ext1 and Ext2 is sufficient for formation of multiple exostoses in mouse ribs and long bones. Bone 48(5): 979-87, May 2011.

Sugito H, Shibukawa Y, Kinumatsu T, Yasuda T, Nagayama M, Yamada S, Minugh-Purvis N, Pacifici M, Koyama E: Ihh signaling regulates mandibular symphysis development and growth. Journal of dental research 90(5): 625-31, May 2011.

Mundy Christina, Yasuda Tadashi, Kinumatsu Takashi, Yamaguchi Yu, Iwamoto Masahiro, Enomoto-Iwamoto Motomi, Koyama Eiki, Pacifici Maurizio: Synovial joint formation requires local Ext1 expression and heparan sulfate production in developing mouse embryo limbs and spine. Developmental biology 351(1): 70-81, Mar 2011.

Koyama Eiki, Yasuda Tadashi, Minugh-Purvis Nancy, Kinumatsu Takashi, Yallowitz Alisha R, Wellik Deneen M, Pacifici Maurizio: Hox11 genes establish synovial joint organization and phylogenetic characteristics in developing mouse zeugopod skeletal elements. Development (Cambridge, England) 137(22): 3795-800, Nov 2010.

Yasuda T, Mundy C, Kinumatsu T, Shibukawa Y, Shibutani T, Grobe K, Minugh-Purvis N, Pacifici M, Koyama E: Sulfotransferase Ndst1 is needed for mandibular and TMJ development. Journal of dental research 89(10): 1111-6, Oct 2010.

Ochiai T, Shibukawa Y, Nagayama M, Mundy C, Yasuda T, Okabe T, Shimono K, Kanyama M, Hasegawa H, Maeda Y, Lanske B, Pacifici M, Koyama E: Indian hedgehog roles in post-natal TMJ development and organization. Journal of dental research 89(4): 349-54, Apr 2010.

Koyama Eiki, Yasuda Tadashi, Wellik Deneen M, Pacifici Maurizio: Hox11 paralogous genes are required for formation of wrist and ankle joints and articular surface organization. Annals of the New York Academy of Sciences 1192: 307-16, Mar 2010.

back to top
Last updated: 02/13/2012
The Trustees of the University of Pennsylvania