Non-operative care of the spine.
Acupuncture to treat chronic pain and promote well being.
Wheel Chair assessment.
Cell and Molecular Biology
Spine
Intervertebral Disc
Selected Publications
Chen K, Tian Z, Shofer FS, Chenna SS, Sandroni DZ, Qin L, Zhang Y: TNFAIP8/TIPE2 inactivation modulates extracellular matrix organization gene expression and preserves the intervertebral disc. Genes & Diseases 101835: 2352-3042, August 2025.
Wang H, Tian Z, Shofer FS, Qin L, Zhang Y: Modest Effects of Age on Inflammatory Markers and Histological Features in the Murine Intervertebral Disc Injury Model. Am J Phys Med Rehabil 10(1), May 2025 Notes: published online ahead of final publication.
Tian Z, Chen K, Shofer FS, Ciesielski B, Wang H, O'Brien WT, Qin L, Zhang Y.: Gene Expression Changes Precede Elevated Mechanical Sensitivity in the Mouse Intervertebral Disc Injury Model. JOR Spine 8(1), Feb 23 2025.
Chen K, Tian Z, Wang H, Enomoto-Iwamoto M, Zhang Y: ADAM8 Inactivation Modulates Cellular Component Assembly Gene Expression in the Mouse Intervertebral Disc. Genes & Diseases 12(3), Nov 2024.
Jiawei Lu, Zuozhen Tian, Frances S Shofer, Ling Qin, Honghong Sun, Yejia Zhang: Tnfaip8 and Tipe2 Gene Deletion Ameliorates Immediate Proteoglycan Loss and Inflammatory Responses in the Injured Mouse Intervertebral Disc. Am J Phys Med Rehabil 103(10): 918-924, Oct 2024.
Li J, Gui T, Yao L, Guo H, Lin YL, Lu J, Duffy M, Zgonis M, Mauck R, Dyment N, Zhang Y, Scanzello C, Seale P, Qin L.: Synovium and infrapatellar fat pad share common mesenchymal progenitors and undergo coordinated changes in osteoarthritis. J Bone Miner Res 39(1): 161-176, Mar 2024.
Chen K, Tian Z, Wang H, Qin L, Enomoto-Iwamoto M, Zhang Y.: Gene Expression Profiles Perturbed by Injury to the Mouse Intervertebral Disc. Am J Phys Med Rehabil 104: 45-50, Jan 2024.
Lu J, Tian Z, Shofer FS, Yao L, Sandroni AZ, Sun H, Qin L, Zhang Y.: Tnfa , Il6 , Cxcl1 , and Adam8 Genes Are the Early Markers After Mouse Tail Intervertebral Disc Injury. Am J Phys Med Rehabil 102(1): 1063-1069, Dec 2023.
Tian Z, Shofer FS, Fan M, Sandroni AZ, Yao L, Han L, Qin L, Enomoto-Iwamoto M, Zhang Y.: ADAM8 inactivation retards intervertebral disc degeneration in mice. Genes Diseases 11(1): 101059, Aug 2023.
Lu K, Wang Q, Jiang H, Li J, Yao Z, Huang Y, Chen J, Zhang Y, Xiao G, Hu X, Luo Z, Yang L, Tong L, Chen D.: Upregulation of β-catenin signaling represents a single common pathway leading to the various phenotypes of spinal degeneration and pain. Bone Res 11(1): 18, Apr 2023.
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Last updated: 01/07/2026
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