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Yejia Zhang, MD, PhD
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Associate Professor of Physical Medicine and Rehabilitation at the Hospital of the University of Pennsylvania
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Staff Physician, Corporal Michael J. Crescenz Department of Veterans Affairs Medical Center, Philadelphia, PA.
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Department: Physical Medicine and Rehabilitation
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Contact information
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Penn Medicine at Rittenhouse
40 1800 Lombard Street/1st Floor
Philadelphia, PA 19146
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40 1800 Lombard Street/1st Floor
Philadelphia, PA 19146
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Office: 215-893-2645
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Publications
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Links
cc Search PubMed for articles
74 Physician profile on Doximity
78 US News Physician Profile
93 University of Pennsylvania Faculty Profile
70 Research Gate Profile
94 WebMD Profile
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cc Search PubMed for articles
74 Physician profile on Doximity
78 US News Physician Profile
93 University of Pennsylvania Faculty Profile
70 Research Gate Profile
94 WebMD Profile
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Education:
21 7 MD 15 (Medicine) c
67 Second Military Medical University, Shanghai, People's Republic of China (PRC), 1989.
21 8 PhD 27 (Cell and Molecular Biology) c
33 University of Pennsylvania, 1997.
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Permanent link21 7 MD 15 (Medicine) c
67 Second Military Medical University, Shanghai, People's Republic of China (PRC), 1989.
21 8 PhD 27 (Cell and Molecular Biology) c
33 University of Pennsylvania, 1997.
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42 Acupuncture to treat chronic pain and promote well being.
1e Wheel Chair assessment.
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d Spine
1a Intervertebral Disc
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Description of Clinical Expertise
32 Non-operative care of the spine.42 Acupuncture to treat chronic pain and promote well being.
1e Wheel Chair assessment.
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Description of Research Expertise
2b Cell and Molecular Biologyd Spine
1a Intervertebral Disc
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13a Chen K, Tian Z, Shofer FS, Chenna SS, Sandroni DZ, Qin L, Zhang Y: TNFAIP8/TIPE2 inactivation modulates extracellular matrix organization gene expression and preserves the intervertebral disc. Genes & Diseases 101835: 2352-3042, August 2025.
145 Wang H, Tian Z, Shofer FS, Qin L, Zhang Y: Modest Effects of Age on Inflammatory Markers and Histological Features in the Murine Intervertebral Disc Injury Model. Am J Phys Med Rehabil 10(1), May 2025 Notes: published online ahead of final publication.
122 Tian Z, Chen K, Shofer FS, Ciesielski B, Wang H, O'Brien WT, Qin L, Zhang Y.: Gene Expression Changes Precede Elevated Mechanical Sensitivity in the Mouse Intervertebral Disc Injury Model. JOR Spine 8(1), Feb 23 2025.
109 Chen K, Tian Z, Wang H, Enomoto-Iwamoto M, Zhang Y: ADAM8 Inactivation Modulates Cellular Component Assembly Gene Expression in the Mouse Intervertebral Disc. Genes & Diseases 12(3), Nov 2024.
157 Jiawei Lu, Zuozhen Tian, Frances S Shofer, Ling Qin, Honghong Sun, Yejia Zhang: Tnfaip8 and Tipe2 Gene Deletion Ameliorates Immediate Proteoglycan Loss and Inflammatory Responses in the Injured Mouse Intervertebral Disc. Am J Phys Med Rehabil 103(10): 918-924, Oct 2024.
164 Li J, Gui T, Yao L, Guo H, Lin YL, Lu J, Duffy M, Zgonis M, Mauck R, Dyment N, Zhang Y, Scanzello C, Seale P, Qin L.: Synovium and infrapatellar fat pad share common mesenchymal progenitors and undergo coordinated changes in osteoarthritis. J Bone Miner Res 39(1): 161-176, Mar 2024.
ff Chen K, Tian Z, Wang H, Qin L, Enomoto-Iwamoto M, Zhang Y.: Gene Expression Profiles Perturbed by Injury to the Mouse Intervertebral Disc. Am J Phys Med Rehabil 104: 45-50, Jan 2024.
128 Lu J, Tian Z, Shofer FS, Yao L, Sandroni AZ, Sun H, Qin L, Zhang Y.: Tnfa , Il6 , Cxcl1 , and Adam8 Genes Are the Early Markers After Mouse Tail Intervertebral Disc Injury. Am J Phys Med Rehabil 102(1): 1063-1069, Dec 2023.
10e Tian Z, Shofer FS, Fan M, Sandroni AZ, Yao L, Han L, Qin L, Enomoto-Iwamoto M, Zhang Y.: ADAM8 inactivation retards intervertebral disc degeneration in mice. Genes Diseases 11(1): 101059, Aug 2023.
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Selected Publications
10f Yao, L.; Wang, H.; Tian, Z.; Shofer, F.S.; Qin, L.; Zhang, Y.: Effects of Age on Intervertebral Disc Tissue Morphology and Gene Expression in the ADAM8-Inactivation Mouse. Cells 15(730), April 2026.13a Chen K, Tian Z, Shofer FS, Chenna SS, Sandroni DZ, Qin L, Zhang Y: TNFAIP8/TIPE2 inactivation modulates extracellular matrix organization gene expression and preserves the intervertebral disc. Genes & Diseases 101835: 2352-3042, August 2025.
145 Wang H, Tian Z, Shofer FS, Qin L, Zhang Y: Modest Effects of Age on Inflammatory Markers and Histological Features in the Murine Intervertebral Disc Injury Model. Am J Phys Med Rehabil 10(1), May 2025 Notes: published online ahead of final publication.
122 Tian Z, Chen K, Shofer FS, Ciesielski B, Wang H, O'Brien WT, Qin L, Zhang Y.: Gene Expression Changes Precede Elevated Mechanical Sensitivity in the Mouse Intervertebral Disc Injury Model. JOR Spine 8(1), Feb 23 2025.
109 Chen K, Tian Z, Wang H, Enomoto-Iwamoto M, Zhang Y: ADAM8 Inactivation Modulates Cellular Component Assembly Gene Expression in the Mouse Intervertebral Disc. Genes & Diseases 12(3), Nov 2024.
157 Jiawei Lu, Zuozhen Tian, Frances S Shofer, Ling Qin, Honghong Sun, Yejia Zhang: Tnfaip8 and Tipe2 Gene Deletion Ameliorates Immediate Proteoglycan Loss and Inflammatory Responses in the Injured Mouse Intervertebral Disc. Am J Phys Med Rehabil 103(10): 918-924, Oct 2024.
164 Li J, Gui T, Yao L, Guo H, Lin YL, Lu J, Duffy M, Zgonis M, Mauck R, Dyment N, Zhang Y, Scanzello C, Seale P, Qin L.: Synovium and infrapatellar fat pad share common mesenchymal progenitors and undergo coordinated changes in osteoarthritis. J Bone Miner Res 39(1): 161-176, Mar 2024.
ff Chen K, Tian Z, Wang H, Qin L, Enomoto-Iwamoto M, Zhang Y.: Gene Expression Profiles Perturbed by Injury to the Mouse Intervertebral Disc. Am J Phys Med Rehabil 104: 45-50, Jan 2024.
128 Lu J, Tian Z, Shofer FS, Yao L, Sandroni AZ, Sun H, Qin L, Zhang Y.: Tnfa , Il6 , Cxcl1 , and Adam8 Genes Are the Early Markers After Mouse Tail Intervertebral Disc Injury. Am J Phys Med Rehabil 102(1): 1063-1069, Dec 2023.
10e Tian Z, Shofer FS, Fan M, Sandroni AZ, Yao L, Han L, Qin L, Enomoto-Iwamoto M, Zhang Y.: ADAM8 inactivation retards intervertebral disc degeneration in mice. Genes Diseases 11(1): 101059, Aug 2023.
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