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Hanako Reyes, Dr. Jill Whelan, Alejandra Fausto, Dr. Nikki Tanneti & Courtney Comar - The Weiss Lab
Katherine Beattie - MD/PhD student, The Luo Lab
Rotonya Carr, MD - The Carr Lab
Julia Eberhard & Eric Rodríguez-López - Immunology Graduate Group
Ronan Lordan, PhD - The FitzGerald Lab
The Juardo Lab poses with a portrait of Dr. Helen O Dickens, the 1st Black woman admitted to the American College of Surgeons & 1st woman to serve in PSOM's OB/GYN faculty.
© Jim Shorter, MA, PhD - Dept. of Biochemistry & Biophysics

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Researchers Uncover Link Between Racial, Ethnic and Socioeconomic Factors and Likelihood of Getting Effective Treatment for Atrial Fibrillation February 26, 2021 Even though the use of rhythm control strategies for treating Paroxysmal Atrial Fibrillation (AF), a common abnormal heart rhythm, have increased overall in the United States, patients from racial and ethnic minority groups and those with lower income were less likely to receive rhythm control treatment - often the preferred treatment - according to new research from the Perelman School of Medicine at the University of Pennsylvania.
Overlooked Cilium Could Be Genetic Key to Common Diseases February 25, 2021 “One of the most exciting implications of our study is that the cilium may represent a common therapeutic target since it appears to be involved in a number of complex diseases,” said the study’s lead author, Theodore Drivas, MD, PhD, a postdoctoral fellow and clinical associate in Internal Medicine.
Patients on a Low-Calorie Diet along with Intensive Behavioral Therapy Lost Nearly Three Times as Much Weight When Taking New Anti-Obesity Medication, Semaglutide, than When Taking Placebo February 24, 2021 A second study of the injectable anti-obesity medication, semaglutide, has confirmed the large weight losses reported in a study earlier this month, establishing the reliability and robustness of this new drug. With obesity affecting more than 40 percent of American adults, the findings could have a major impact on weight management in primary care and other settings.
People with Psoriatic Disease Taking Methotrexate Are More Likely to Develop Liver Disease Compared to Those with Rheumatoid Arthritis on Methotrexate February 23, 2021 Using the immunosuppressant medication methotrexate to treat psoriasis and psoriatic arthritis is more likely to lead to serious liver complications than using the same medication to treat rheumatoid arthritis, according to research from the Perelman School of Medicine at the University of Pennsylvania.
Five Years Later: Penn-developed CAR T Therapy Shows Long-lasting Remissions in Non-Hodgkin Lymphomas February 18, 2021 A significant number of non-Hodgkin lymphoma (NHL) patients in a Penn Medicine-initiated clinical trial continue to be in remission five years after receiving the chimeric antigen receptor (CAR) T cell therapy Kymriah™, researchers in Penn’s Abramson Cancer Center reported today in the New England Journal of Medicine.

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BACH2 enforces the transcriptional and epigenetic programs of stem-like CD8<sup>+</sup> T cells.
Yao C, Lou G, Sun HW, Zhu Z, Sun Y, Chen Z, Chauss D, ... Nature immunology. 2021 Mar;22(3):370-380 Epub 2021 Feb 11
SARS-CoV-2 transmission via speech-generated respiratory droplets.
Bax A, Bax CE, Stadnytskyi V, Anfinrud P The Lancet. Infectious diseases. 2021 Mar;21(3):318 Epub 2020 Sep 11
Lessons learned from a progressive supranuclear palsy trial.
Grossman M The Lancet. Neurology. 2021 Mar;20(3):162-163
Outcomes by Clinical and Molecular Features in Children With Medulloblastoma Treated With Risk-Adapted Therapy: Results of an International Phase III Trial (SJMB03).
Gajjar A, Robinson GW, Smith KS, Lin T, Merchant TE, Chintagumpala M, Mahajan A, ... Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2021 Mar 1;39(7):822-835 Epub 2021 Jan 6
In vivo CD8<sup>+</sup> T cell CRISPR screening reveals control by Fli1 in infection and cancer.
Chen Z, Arai E, Khan O, Zhang Z, Ngiow SF, He Y, Huang H, ... Cell. 2021 Feb 25

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