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Devraj Basu, M.D., Ph.D., F.A.C.S.Assistant Professor of Otorhinolaryngology: Head and Neck Surgery at the Hospital of the University of Pennsylvania and the Veteran's Administration Medical Center
Full Member, Abramson Cancer Center
Department: Otorhinolaryngology: Head and Neck Surgery
Contact information
5 Ravdin/Silverstein
Hospital of the University of Pennsylvania 3400 Spruce Street Philadelphia, PA 19104
Education:
Sc.B (Biology) Brown University, 1994. Ph.D. (Immunology) Washington University School of Medicine, 2001. M.D. (Medicine) Washington University School of Medicine, 2001.
Post-Graduate Training
Intern, Surgery, Barnes-Jewish Hospital, 2001-2002. Resident, Otolaryngology, Barnes-Jewish Hospital, 2002-2005. Chief Resident, Otolaryngology, Barnes-Jewish Hospital, 2005-2006. Fellow, Head and Neck Surgery and Microvascular Reconstruction, Hospital of the University of Pennsylvania, 2006-2007.
Certifications
Permanent linkAmerican Board of Otolaryngology, 2007. Description of Research ExpertiseSquamous cell carcinoma biology3-dimensional in vitro cancer models Tumor heterogeneity Epithelial to mesenchymal transition Tumor cell quiescence Description of Clinical ExpertiseSurgical treatment of disorders of the head and neckBenign and malignant tumors of the head and neck Oral Cancer Laryngeal Cancer Salivary Cancer Sinonasal Cancer Skin Cancer Thyroid and parathyroid surgery Transoral laser surgery Head and neck trauma Endoscopic sinus surgery Selected PublicationsFacompre N, Nakagawa H, Herlyn M, Basu D: Stem-like cells and therapy resistance in squamous cell carcinomas. Adv. Pharmacol. 65: 235-265, October 2012.Basu D, Ngyen TK, Montone KT, Zhang BS, Wang L, Diehl JA, Rustgi AK, Lee JT, Weinstein GS, Herlyn M: Evidence for mesenchymal-like subpopulations within squamous cell carcinomas possessing chemoresistance and phenotypic plasticity. Oncogene 29(29): 4170-4182, July 2010. Roesch A,Fukunaga-Kalabis M, Schmidt EC, Zabierowski SE, Brafford PA, Vultur A, Basu D, Gimotty P, Vogt T,4 Herlyn M: A Temporarily Distinct Subpopulation of Slow-Cycling Melanoma Cells Is Required for Continuous Tumor Growth. Cell 141(4): 583-594, May 2010. Basu D, Montone KT, Wang LP, Gimotty PA, Hammond R, Diehl JA, Rustgi AK, Lee JT, Rasanen K, Weinstein GS, Herlyn M. : Detecting and targeting mesenchymal-like subpopulations within squamous cell carcinomas. Cell Cycle 10(12): 2008-2016, June 2011. Ohashi S, Natsuizaka M, Naganuma S, Kagawa S, Kimura S, Itoh H, Kalman RA, Nakagawa M, Darling DS, Basu D, Gimotty PA, Klein-Szanto AJ, Diehl JA, Herlyn M, Nakagawa H.: A NOTCH3-mediated squamous cell differentiation program limits expansion of EMT competent cells that express the ZEB transcription factors. Cancer Research 71(21): 6836-47, November 2011. Leibowitz JM, Montone KT, Basu D: Warthin tumor presenting as a fungal abscess in an immunocompetent host: case report and review of the literature. Head Neck 31(1): 133-6, Jan 2009. Basu D, Siegel BA, McDonald DJ, Nussenbaum B: Detection of occult bone metastasis from head and neck squamous cell carcinoma: impact of PET/CT imaging. Arch Otolaryngol Head Neck Surg 133(8): 801 - 805, August 2007. Basu D, Herlyn M: Commentary: defining microenvironments within mouse models that enhance tumor aggressiveness. Cancer Biol Ther 8(4): 380-1, February 2009. Basu D, Haughey BH, Hartman JM: Determinants of Success in Endoscopic CSF Leak Repair. Otolaryngol Head Neck Surg 135(5): 769 - 773, November 2006. Haddad C, Basu D: Differential Diagnosis of Salivary Gland Disturbance and Halitosis Differential Diagnosis in Otolaryngology: Head and Neck Surgery. W. Stewart (eds.). Thieme, November 2010.
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