Jason D. Christie, MD, MSCE
Hospital of the University of Pennsylvania
Center for Clinical Epidemiology and Biostatistics
University of Pennsylvania School of Medicine
423 Guardian Drive
717 Blockley Hall
Philadelphia, PA 19104
Fax: (215) 573-0198
Brown University, 1989.
Columbia University, 1993.
M.S.C.E. (Clinical Epidemiology)
University of Pennsylvania, 2002.
Resident in Medicine, Hospital of the University of Pennsylvania, 1993-1996.
Chief Medical Resident, Hospital of the University of Pennsylvania, 1996-1997.
Fellow, Division of Pulmonary and Critical Care Medicine, Hospital of the University of Pennsylvania , 1997-2000.
Fellow, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania, 1998-2000.
Internal Medicine, 1996.
Pulmonary Medicine, 2000.
Critical Care Medicine, 2001.
Internal Medicine, 2006.
Pulmonary Disease, 2009.
Critical Care Medicine, 2010.
Description of Research ExpertiseDr. Christie's translational research studies involve the role of oxidative stress, coagulation/fibrinolysis and inflammatory pathways in acute lung injury following lung transplantation (termed primary graft dysfunction); somatic genetic variation; gene expression; and protein biomarkers in the etiology and pathogenesis of acute lung injury in the transplant, sepsis, and trauma populations.
Selected PublicationsMeyer Nuala J, Ferguson Jane F, Feng Rui, Wang Fan, Patel Parth N, Li Mingyao, Xue Chenyi, Qu Liming, Liu Yichuan, Boyd John H, Russell James A, Christie Jason D, Walley Keith R, Reilly Muredach P: A Functional Synonymous Coding Variant in the IL1RN Gene Associates with Survival in Septic Shock. American journal of respiratory and critical care medicine Aug 2014.
Whittaker Stacey-Ann, Fuchs Barry D, Gaieski David F, Christie Jason D, Goyal Munish, Meyer Nuala J, Kean Craig, Small Dylan S, Bellamy Scarlett L, Mikkelsen Mark E: Epidemiology and outcomes in patients with severe sepsis admitted to the hospital wards. Journal of critical care Jul 2014.
Shashaty MGS, Kalkan E, Bellamy SL, Reilly JP, Holena DN, Cummins K, Lanken PN, Feldman HI, Reilly MP, Udupa JK, Christie JD: Computed tomography-defined abdominal adiposity is associated with acute kidney injury in critically ill trauma patients. Critical Care Medicine 42(7): 1619-28, July 2014.
Todd Jamie L, Christie Jason D, Palmer Scott M: Update in lung transplantation 2013. American journal of respiratory and critical care medicine 190(1): 19-24, Jul 2014.
Reilly John P, Bellamy Scarlett, Shashaty Michael G S, Gallop Robert, Meyer Nuala J, Lanken Paul N, Kaplan Sandra, Holena Daniel N, May Addison K, Ware Lorraine B, Christie Jason D: Heterogeneous phenotypes of acute respiratory distress syndrome after major trauma. Annals of the American Thoracic Society 11(5): 728-36, Jun 2014.
Shah, R.J.* Emtiazjoo, A.M.* Diamond, J.M. Smith, P.A. Roe, D.W. Wille, K.M. Orens, J.B. Ware, L.B. Weinacker, A. Lama, V.N. Bhorade, S. Palmer, S.M. Crespo, M. Lederer, D.J. Cantu, E. Eckert, G.J. Christie, J.D.* Wilkes, D.S.* (*contriubted equally).: Plasma Complement Levels are Associated with Primary Graft Dysfunction and Mortality after Lung Transplantation. American Journal of Respiratory and Critical Care Medicine 189(12): 1564-7, Jun 2014.
Cohen David G, Christie Jason D, Anderson Brian J, Diamond Joshua M, Judy Ryan P, Shah Rupal J, Cantu Edward, Bellamy Scarlett L, Blumenthal Nancy P, Demissie Ejigayehu, Hopkins Ramona O, Mikkelsen Mark E: Cognitive function, mental health, and health-related quality of life after lung transplantation. Annals of the American Thoracic Society 11(4): 522-30, May 2014.
Wong HR, Lindsell CJ, Pettilä V, Meyer NJ, Thair SA, Karlsson S, Russell JA, Fjell CD, Boyd JH, Ruokonen E, Shashaty MG, Christie JD, Hart KW, Lahni P, Walley KR: A Multibiomarker-Based Outcome Risk Stratification Model for Adult Septic Shock. Critical Care Medicine 42(4): 781-9, April 2014.
Wong Hector R, Lindsell Christopher J, Pettilä Ville, Meyer Nuala J, Thair Simone A, Karlsson Sari, Russell James A, Fjell Christopher D, Boyd John H, Ruokonen Esko, Shashaty Michael G S, Christie Jason D, Hart Kimberly W, Lahni Patrick, Walley Keith R: A multibiomarker-based outcome risk stratification model for adult septic shock*. Critical care medicine 42(4): 781-9, Apr 2014.
Reilly John P, Meyer Nuala J, Shashaty Michael G S, Feng Rui, Lanken Paul N, Gallop Robert, Kaplan Sandra, Herlim Maximilian, Oz Nathaniel L, Hiciano Isabel, Campbell Ana, Holena Daniel N, Reilly Muredach P, Christie Jason D: ABO blood type A is associated with increased risk of ARDS in whites following both major trauma and severe sepsis. Chest 145(4): 753-61, Apr 2014.
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