Jason D. Christie - Faculty Biosketch

Jason D. Christie, MD, MSCE

Paul F. Harron, Jr. Family Professor

Member, Biomedical Graduate Group, Perelman School of Medicine at the University of Pennsylvania, Department of Biostatistics and Epidemiology

Senior Scholar, Center for Clinical Epidemiology and Biostatistics, Perelman School of Medicine at the University of Pennsylvania

Adjunct Investigator, Institute for Environmental Medicine, Perelman School of Medicine at the University of Pennsylvania

Chief, Pulmonary, Allergy, and Critical Care Division, Perelman School of Medicine at the University of Pennsylvania

Executive Committee, Penn Institute for Immunology, Perelman School of Medicine at the University of Pennsylvania

3 5f

Department: Medicine

4 1 b

46 Contact information
5e

Division of Pulmonary and Critical Care Medicine
32 Hospital of the University of Pennsylvania
3a Center for Clinical Epidemiology and Biostatistics
35 University of Pennsylvania School of Medicine
1a 423 Guardian Drive
34 221 Blockley Hall
Philadelphia, PA 19104

30 Office: (215) 573-3209
34 Fax: (215) 573-0198
24

Email:
jchristi@upenn.edu

4 3 23

1f Graduate Group Affiliations 8

Graduate Group in Epidemiology and Biostatistics

3 1d

18 Publications
23

8a 6f

26 Search PubMed for articles c

3 2 4 b 1f

13 Education:
21 a Sc.B. 16 (Chemistry) c
29 Brown University, 1989.
21 9 M.D. 15 (Medicine) c
2c Columbia University, 1993.
21 d M.S.C.E. 22 (Clinical Epidemiology) c
33 University of Pennsylvania, 2002.
c

3 27

Links
d6 Search PubMed for articles
42 Center for Clinical Epidemiology and Biostatistics faculty webpage
9f Institute for Translational Medicine and Therapeutics
c

5 21

1f Post-Graduate Training
24 5e Resident in Medicine, Hospital of the University of Pennsylvania, 1993-1996.
24 60 Chief Medical Resident, Hospital of the University of Pennsylvania, 1996-1997.
24 83 Fellow, Division of Pulmonary and Critical Care Medicine, Hospital of the University of Pennsylvania , 1997-2000.
24 74 Fellow, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania, 1998-2000.
c

3 25

17 Certifications
28 2a Internal Medicine, 1996.
28 2b Pulmonary Medicine, 2000.
28 2f Critical Care Medicine, 2001.
28 25 Epidemiology, 2003.
28 2a Internal Medicine, 2006.
28 2a Pulmonary Disease, 2009.
28 2f Critical Care Medicine, 2010.
c

3 8b Permanent link
2 29

b6 > Perelman School of Medicine > Faculty > Details a

1e 1d

Description of Research Expertise

206 Dr. Christie's career is focused on translational research studies of the risks, pathogenesis, treatment, and outcomes of acute lung injury in the transplant and non-transplant human populations. His research integrates new knowledge generated from bench studies with epidemiology approaches in well-phenotyped, large human populations to generate new definitions of human syndromes, improved diagnostics and prognostics, and targeted therapy approaches in advanced lung diseases and critical illness.
8
2c9 Dr. Christie is the founder of the lung transplant outcomes group (LTOG), which is a multicentered cohort study the etiology and pathogenesis of acute lung injury following lung transplantation (termed primary graft dysfunction). Active LTOG research themes focus on the mechanisms of clinical factors that elevate PGD risk, including donor smoke exposure, recipient obesity and body composition, pulmonary hypertension, alterations in lung microbiome, and autoimmunity to lung collagens. His multidisciplinary lung transplant research focuses on genetics, innate immunity, regulatory T-cells, innate lymphoid cell (ILC) populations in the lung, ischemia reperfusion injury, inflammation, and autoimmunity.
26 29

Selected Publications

1a0 Patrick W Mellors , Ana N Lange , Bruno Casino Remondo , Maksim Shestov , Joseph D Planer , Andrew R Peterson, Yun Ying , Su Zhou , Jason D Christie , Joshua M Diamond , Edward Cantu , Maria C Basil , Saar Gill : Shared roles of immune and stromal cells in the pathogenesis of human bronchiolitis obliterans syndrome. JCI Insite April 2025.

19e Claire E Fishman 1, Ciara Walshe 2, Tamara Claridge 2, Stephanie Witek 2, Krishna Pandya 3, Jason D Christie 3, Joshua M Diamond 3, Michaela R Anderson 4: Tolerability and Effectiveness of Glucagon-Like Peptide-1 Receptor Agonists in Lung Transplant Recipients: A Single Center Report. Transplantation Proceedings Page: 342-347, March 2025.

1a2 Brittany Koons, James D Mendez, Michaela R Anderson, Edward Cantu, Matthew Hartwig, Christian Merlo, Krishna Pandya, Emily Vail, Jonathan P Singer, Jason D Christie : Clinical and System-Level Factors Driving Donor Lung Utilization Decisions: A Qualitative Study. Annals of the American Thoracic Society March 2025 Notes: Online ahead of print.

1d6 Felicia Y Ho, Xingmei Wang, Douglas E Schaubel, Mauer Biscotti 3rd, Marisa Cevasco, Aditya G Parikh, Meeta P Kerlin, Jason D Christie, Peter P Reese, Emily A Vail : Heart donation and transplant recipient survival outcomes from deceased organ donors managed in hospital-based vs independent donor care units. The Journal of Heart and Lung Transplantation March 2025 Notes: Online ahead of print.

190 Patrick K Gleeson 1, Knashawn H Morales 2, Meeta Prasad Kerlin 3, Olajumoke O Fadugba 4, Andrea J Apter 4, Jason D Christie 5, Blanca E Himes 2: Racial differences in odds of asthma exacerbations among Aspergillus fumigatus-sensitized adults with asthma. Annals of Allergy, Asthma and Immunology 134(2: 190-197, February 2025.

1ca Tatsuki Koyama, Zhiguo Zhao, John R Balmes, Carolyn S Calfee , Michael A Matthay, John P Reilly, Mary K Porteous, Joshua M Diamond, Jason D Christie, Edward Cantu, Lorraine B Ware; Lung Transplant Outcomes Group: Long-term air pollution exposure and the risk of primary graft dysfunction after lung transplantation. The Journal of Heart and Lung Transplant 44(1): 64-74. January 2025.

176 Patrick K Gleeson, Knashawn H Morales, Timothy M Buckey, Olajumoke O Fadugba, Andrea J Apter , Jason D Christie, Blanca E Himes : Associations of aeroallergen testing with reduced oral corticosteroid bursts among adults with asthma. The Journal of Allergy and Clinical Immunology 17;4, October 2024.

1a6 Patrick K Gleeson, Knashawn H Morales, Meeta Prasad Kerlin, Olajumoke O Fadugba, Andrea J Apter, Jason D Christie, Blanca E Himes: Racial differences in odds of asthma exacerbations among Aspergillus fumigatus-sensitized adults with asthma. Annals Of Allergy, Asthma & Immunology Page: 1206(24)01504-7, September 2024 Notes: Online ahead of print.

1c6 Adora N Moneme, Mallory Hunt, Jacqueline Friskey, Madeline McCurry, Dun Jin, Joshua M Diamond, Michaela R Anderson, Emily S Clausen, Aya Saleh, Allie Raevsky, Jason D Christie, Douglas Schaubel, Jesse Hsu, A Russell Localio, Robert Gallop, Edward Cantu : Evaluating US Multiple Listing Practices in Lung Transplantation: Unveiling Hidden Disparities. Chest August 2024 Notes: Online ahead of print. 14

202 Tatsuki Koyama, Zhiguo Zhao, John R Balmes, Carolyn S Calfee, Michael A Matthay, John P Reilly, Mary K Porteous, Joshua M Diamond, Jason D Christie, Edward Cantu, Lorraine B Ware; Lung Transplant Outcomes Group: Long-term air pollution exposure and the risk of primary graft dysfunction after lung transplantation. J Heart Lung Transplant. The Journal of Heart and Lung Transplantation 24: 1053-2498, July 2024 Notes: Online ahead of print.

2c

7 1d

2c back to top
26 Last updated: 10/01/2025
34 The Trustees of the University of Pennsylvania c