Anupma Nayak
Associate Professor of Pathology and Laboratory Medicine at the Hospital of the University of Pennsylvania
Attending Pathologist, Hospital of the University of Pennsylvania
Director, Breast Pathology Fellowship Program, Department of Pathology and Laboratory Medicine,Perelman School of Medicine and Hospital of the University of Pennsylvania
Director, Tumor Tissue and Biobank (TTAB), Department of Pathology and Laboratory Medicine, Hospital of the University of Pennsylvania
Department: Pathology and Laboratory Medicine
Contact information
Associate Professor
Dept. of Pathology and Laboratory Medicine
Hospital of the University of Pennsylvania
Perelman School of Medicine
3400 Spruce St.
6 Founders
Philadelphia, PA 19104
Dept. of Pathology and Laboratory Medicine
Hospital of the University of Pennsylvania
Perelman School of Medicine
3400 Spruce St.
6 Founders
Philadelphia, PA 19104
Office: 2156624899
Publications
Education:
MBBS (Medicine)
King George Medical College, Lucknow, India, 1997.
MBBS (Medicine)
King George Medical College, Lucknow, India, 1997.
Post-Graduate Training
Intern, Dr. Shyama Prasad Mukherjee Hospital (Civil Hospital), Lucknow, India , 1997-1998.
Pathology, All India Institute of Medical Sciences, New Delhi, India, 1999-2001.
Senior Resident, Pathology, All India Institute of Medical Sciences, New Delhi, India, 2002-2005.
Resident, Pathology, NSLIJHS-Albert Einstein College of Medicine at Long Island Jewish Medical Center, NY, USA , 2007-2010.
Chief Resident, Department of Pathology and Lab Medicine, NSLIJHS-Albert Einstein College of Medicine at Long Island Jewish Medical Center, NY , 2009-2010.
Fellow, Selective Breast Pathology, University of Texas- MD Anderson Cancer Center, Houston, Texas, USA, 2010-2011.
Permanent linkIntern, Dr. Shyama Prasad Mukherjee Hospital (Civil Hospital), Lucknow, India , 1997-1998.
Pathology, All India Institute of Medical Sciences, New Delhi, India, 1999-2001.
Senior Resident, Pathology, All India Institute of Medical Sciences, New Delhi, India, 2002-2005.
Resident, Pathology, NSLIJHS-Albert Einstein College of Medicine at Long Island Jewish Medical Center, NY, USA , 2007-2010.
Chief Resident, Department of Pathology and Lab Medicine, NSLIJHS-Albert Einstein College of Medicine at Long Island Jewish Medical Center, NY , 2009-2010.
Fellow, Selective Breast Pathology, University of Texas- MD Anderson Cancer Center, Houston, Texas, USA, 2010-2011.
Description of Itmat Expertise
Breast CancerGenitourinary Cancers
Description of Research Expertise
Breast CancerSelected Publications
Thacker G, Henry S, Nandi A, Debnath R, Singh S, Nayak A, Susnik B, Boone MM, Zhang Q, Kesmodel SB, Gumber S, Das GM, Kambayashi T, Dos Santos CO, Chakrabarti R.: Immature natural killer cells promote progression of triple-negative breast cancer. Sci Transl Med 15(686), Mar 2023 Notes: Epub.Adam A Kraya, Kara N Maxwell, Monika A Eiva, Bradley Wubbenhorst, John Pluta, Michael Feldman, Anupma Nayak, Daniel J Powell Jr, Susan M Domchek, Robert H Vonderheide, Katherine L Nathanson : PTEN Loss and BRCA1 Promoter Hypermethylation Negatively Predict for Immunogenicity in BRCA-Deficient Ovarian Cancer. JCO Precis Oncol Feb 2023.
Khoury T, Rosa M, Nayak A, Karabakhtsian R, Fadare O, Li Z, Turner B, Fang Y, Kumarapeli A, Li X, Numbere N, Villatoro T, Wang JG, Sadeghi S, Attwood K, George A, Bhargava R.: Clinicopathologic Predictors of Clinical Outcomes in Mammary Adenoid Cystic Carcinoma: A Multi-institutional Study. Modern Pathology 36(2), Feb 2023.
Kara Maxwell, et al.: Biallelic BRCA loss and homologous recombination deficiency in non-breast/ovarian tumors in germline BRCA1/2 carriers. JCO Precision Oncology 2023.
Shah JB, Pueschl D, Wubbenhorst B, Fan M, Pluta J, D'Andrea K, Hubert AP, Shilan JS, Zhou W, Kraya AA, Llop Guevara A, Ruan C, Serra V, Balmaña J, Feldman M, Morin PJ, Nayak A, Maxwell KN, Domchek SM, Nathanson KL.: Analysis of matched primary and recurrent BRCA1/2 mutation-associated tumors identifies recurrence-specific drivers. Nat Commun. 13(1), Nov 2022.
Ajeya Nandi, Rahul Debnath, Anupma Nayak, Tsun Ki Jerrick To, Gatha Thacker, Megan Reilly, Sanjeev Gumber, Ilias Karagounis, Ning Li, Christopher J Lengner, Malay Haldar, Alana L Welm, Andres M Blanco, Christoforos Thomas, Rumela Chakrabarti : Dll1-Mediated Notch Signaling Drives Tumor Cell Cross-talk with Cancer-Associated Fibroblasts to Promote Radioresistance in Breast Cancer. Cancer Res 82(20): 3718-3733, October 2022.
Anna Budina, Sahar J Farahani, Priti Lal, Anupma Nayak: Subcategorization of T1 Bladder Cancer on Biopsy and Transurethral Resection Specimens for Predicting Progression. Arch Pathol Lab Medicine 146(9): 1131-1139, Sept 2022 Notes: Corresponding author.
Emily A Verbus, Alexander J Rossi, Amy S Clark, Neil K Taunk, Anupma Nayak, Jonathan M Hernandez, Julia C Tchou: Preoperative Use of a Radiation Boost to Enhance Effectiveness of Immune Checkpoint Blockade Therapy in Operable Breast Cancer. Ann Surg Oncol 29(3): 1530-1532, Mar 2022 Notes: Co-author.
Adeseye Adekeye, Divyansh Agarwal, Anupma Nayak, Julia Tchou: PTGES3 is a Putative Prognostic Marker in Breast Cancer. J Surg Res 271: 154-162, March 2022.
Sarkis Hamalian, Robert Güth, Farhana Runa, Francesca Sanchez, Eric Vickers, Megan Agajanian, Justin Molnar, Tuan Nguyen, Joshua Gamez, Jonathan D Humphries, Anupma Nayak, Martin J Humphries, Julia Tchou, Ioannis K Zervantonakis, Jonathan A Kelber: A SNAI2-PEAK1-INHBA stromal axis drives progression and lapatinib resistance in HER2-positive breast cancer by supporting subpopulations of tumor cells positive for antiapoptotic and stress signaling markers. Oncogene Aug 2021 Notes: Co-author.