Welcome to the Penn Epigenetics Program
The mission of the UPenn Epigenetics Program is to advance epigenetics research at the Perelmen School of Medicine by bringing together diverse programs performing epigenetics research or that wish to perform epigenetic research so that synergies, new insights, and therapeutic approaches can emerge towards the ultimate goal of improving human health.
Shelley L. Berger, Ph.D., Director
Kenneth S. Zaret, Ph.D., Co-Director
New and Upcoming Events
Epigenetics Program Meeting
Thursday, June 13, 2013
4:00pm, room 9-100 Smilow
Emily Bernstein, Ph.D., Mount Sinai Hospital
"Histone variants in development and disease"
Niraj Lodhi, Ph.D., Fox Chase Cancer Center
"PARP1 marks mitotic chromatin and regulates post-mitotic transcription"
A chromatin link to caste identity in the carpenter ant Camponotus floridanus
Simola DF, Ye C, Mutti NS, Dolezal K, Bonasio R, Liebig J, Reinberg D, Berger SL
Nucleosome positioning paper
Kaestner lab at UPenn
Facilitators and impediments of the pluripotency reprogramming factors' initial engagement with the genome.
Soufi A, Donahue G, Zaret KS.
Cell. 2012 Nov 21;151(5):994-1004
Low-hanging fruit: targeting Brdt in the testes.
Bryant JM, Berger SL.
EMBO J. 2012 Oct 3;31(19):3788-9
Tissue-specific mitotic bookmarking by hematopoietic transcription factor GATA1.
Kadauke S, Udugama MI, Pawlicki JM, Achtman JC, Jain DP, Cheng Y, Hardison RC, Blobel GA. Cell. 2012 Aug 17;150(4):725-37
Controlling long-range genomic interactions at a native locus by targeted tethering of a looping factor.
Deng W, Lee J, Wang H, Miller J, Reik A, Gregory PD, Dean A, Blobel GA.
Cell. 2012 2012 Jun 8;149(6):1233-44
Foxa1 and Foxa2 are essential for sexual dimorphism in liver cancer.
Li Z, Tuteja G, Schug J, Kaestner KH.
Cell. 2012 Jan 20;148(1-2):72-83
Research regarding mouse ENCODE project has recently been release. For a short write-up and related info, click here.
Information regarding the new NIH U54 "Epigenetics and Human Reproduction Center"
will be announced soon!
EPIGENETICS ROADMAP PROJECT
The Roadmap Project, sponsored by NIH, provides convergence of epigenomic data on this website: More info can be found in our research section.