Endoderm Symposium: Development, Disease and Regeneration Perelman School of Medicine The Penn Center for Pulmonary Biology Penn Institute for Diabetes, Obesity and Metabolism The Joing Penn-CHOP- Center for Digestive, Liver, and Pancreatic Medicine The CHOP Research Affinity Group in ES/iPS Cells

Agenda

April 24

Developing a career in biomedical research:
Learn from the experts

3:30 - 4:00 PM Brigid Hogan, PhD, FRS
George Barth Geller Professor
Chair, Department of Cell Biology
Duke University
Topic: How to have a career in biomedical research

4:00 - 4:15 PM

Raymond Soccio, MD, PhD
Assistant Professor of Medicine
Division of Endocrinology, Diabetes, and Metabolism
Perelman School of Medicine
University of Pennsylvania
Topic: Wait until you're ready... but there's almost no such thing as ready

4:15 - 4:30 PM Christina Twyman-Saint Victor, MD
Assistant Professor of Medicine
Division of Gastroenterology University
Perelman School of Medicine
University of Pennsylvania
Topic: Sometimes it is better to be lucky than good

4:30 - 5:00 PM Roundtable Discussion
Moderator: Brigid Hogan, Ph.D. FRS
Raymond Soccio, MD, PhD
Christina Twyman-Saint Victor, MD
Rajan Jain, MD, Ph.D.
Andrew Vaughan, Ph.D.
5:00 - 6:00 PM Reception

April 25

 
9:00 AM Welcome Jonathan A. Epstein, MD
Executive Vice Dean and Chief Scientific Officer
Perelman School of Medicine
9:15 AM Keynote Address
Hans Clevers MD, PhD
Professor in Immunology
Professor of Molecular Genetics
Hubrecht Institute in Utrecht
Utrecht, Netherlands
Topic: Stem cell-grown organoids as models for human disease
10:00 AM Kenneth S. Zaret, PhD
Joseph Leidy Professor
Director, Institute for Regenerative Medicine
Department of Cell and Developmental Biology
Perelman School of Medicine
University of Pennsylvania
Topic: Chromatin control of endoderm development
10:30 AM Break
10:45 AM Ben Z. Stanger, MD, PhD
Associate Professor of Medicine
Abramson Family Cancer Research Institute
Division of Gastgroenterology
Perelman School of Medicine
University of Pennsylvania
Topic: Endoderm in motion: Distinct EMT programs driving metastasis
11:15 AM Short Talk – Leonardo Cardenas, PhD
Post Doctoral Fellow – Dr. Paul Gadue Lab
Topic: Modeling MODY3 with human pluripotent stem cells
11:30 AM Andrew Vaughan, PhD
Assistant Professor of Medicine
School of Veterinary Medicine
University of Pennsylvania
Topic: Local lung hypoxia determines epithelial fate decisions during alveolar regeneration 
12:00 PM Short Talk – Veronique Giroux, PhD
Post Doctoral Fellow – Dr. Anil Rustgi Lab
Topic: Identification and characterization of a novel long-lived progenitor cell in the mouse squamous esophagus
12:15 - 2:00 PM Lunch and Poster Session

2:00 PM Brigid Hogan, PhD, FRS
George Barth Geller Professor
Chair, Department of Cell Biology
Duke University
Topic: Towards defining the Alveolar Type2 stem cell niche
2:30 PM Christopher Lengner, PhD
Assistant Professor,
Department of Biomedical Sciences
Director, Center for Animal Transgenesis
School of Veterinary Medicine
University of Pennsylvania
Topic: Organotypic models of human telomere disorders
3:00 PM Break
3:15 PM Jayaraj Rajagopal, MD
Center for Regenerative Medicine
Massachusetts General Hospital
Associate Professor
Harvard Medical School
Harvard Stem Cell Institute
Topic: Tissue logic in the airway epithelium
3:45 PM Christopher V. Wright, D. Phil.
Professor of Cell and Developmental Biology
Louise B. McGavock Chair
Director, Program in Developmental Biology
Vanderbilt University School of Medicine
Topic: New ideas on endocrine-cell formation in the pancreas - an organ built from a rapidly expanding plexus-type epithelium
4:15 PM Edward E. Morrisey, PhD
Closing statements and Poster Award Announcements
4:30 - 6:00 PM Reception and Poster Session