We aim to further our understanding of the genome by integrating large-scale genomic datasets. We develop computational methods to exploit multi-dimensional genomic/epigenomic landscapes to understand cell-type specific or spatio-temporal gene regulation. Using computational integrative approaches, we also study transcriptional mechanisms controlling cell differentiation and cell identify. Our area of research include studying gene regulations in adipocyte, liver, cancer cells and stem cell differentiation.

University of Pennsylvania
12-111 Translational Research Center
3400 Civic Center Blvd 
Philadelphia, PA, 19104-6160

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