Roy Hoshi Hamilton - Faculty Biosketch

Roy Hoshi Hamilton, MD, MS, FAAN, FANA

Professor of Neurology

Director, Laboratory for Cognition and Neural Stimulation, University of Pennsylvania

Director, Brain Stimulation, Translation, Innovation, and Modulation (brainSTIM) Center, University of Pennsylvania

Faculty, Brain Science Center, University of Pennsylvania

Advisory Board Member, Clinical Neurosciences Training Program (CNST), Perelman School of Medicine, University of Pennsylvania

Chair Elect, Faculty Senate, University of Pennsylvania

Special Advisor to the Dean, Perelman School of Medicine

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Department: Neurology

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46 Contact information
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Goddard Laboratories, Room 518
22 University of Pennsylvania
35 3710 Hamilton Walk
Philadelphia, PA 19104

2e Office: 215-573-7065
32 Fax: 215-898-1982
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1f Graduate Group Affiliations 8

Neuroscience

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Links
a3 Penn Brain Science, Translation, Innovation, and Modulation(brainSTIM) Center
78 Laboratory for Cognition and Neural Stimulation
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13 Education:
21 9 B.A. 28 (Psychology, magna cum laude) c
2b Harvard University, 1995.
21 9 M.D. 20 (Medicine, cum laude) c
2f Harvard Medical School, 2001.
21 9 M.S. 2b (Health Sciences and Technology) c
3f Massachusetts Institute of Technology , 2001.
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1f Post-Graduate Training
24 73 Intern in Internal Medicine, University of California School of Medicine, Los Angeles, 2001-2002.
24 4f Resident in Neurology, University of Pennsylvania, 2002-2005.
24 57 Fellow in Cognitive Neurology, University of Pennsylvania, 2005-2007.
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17 Certifications
28 43 American Board of Psychiatry and Neurology, 2006.
28 67 American Board of Psychiatry and Neurology, Maintenance of Certification (MOC), 2016.
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3 90 Permanent link
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b6 > Perelman School of Medicine > Faculty > Details a

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Description of Research Expertise

25f My research focus is on the characteristics and limits of functional neuroplasticity in the adult human brain. I investigate how the brain reorganizes itself in response to injury, and whether or not it is possible to enhance the brain’s potential for reorganization in order to speed rehabilitation using noninvasive electrical or magnetic brain stimulation. A second area of interest for me is on the use of noninvasive brain stimulation to elucidate and enhance mechanisms of cognition in healthy individuals, and the biological, social, and ethical implications of neural enhancement.
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Description of Clinical Expertise

a9 I principally treat patients suffering from dementia. I also have expertise in evaluating and treating patients with cognitive deficits following stroke.
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Description of Other Expertise

146 I am is deeply involved in issues related to diversity in medicine, inclusion, and health equity. I am one of the Assistant Deans for Diversity and Inclusion at the Perelman School of Medicine and I am the Vice Chair for Diversity and Inclusion in the Department of Neurology at the University of Pennsylvania.
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Selected Publications

185 Stites, S.D., Lee, B.N., Kuz, C., Adams, M., Harkins, K., Xie, S., Walke, L., Pansak, P., Hamilton, R.: An online vignette study of diagnostic testing: Racial and ethnic differences in Alzheimer’s Disease diagnosis confidence and stigma. Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring Oct 2025.

1e7 Masson-Trottier, M., Tippett, D.C., Rapp, B., Vnenchak, L., Harvey, D.Y., Roncero, C., Chertkow, H., Hamilton, R.H., Hillis, A., Tsapkini, K. : Protocol for a multisite study on the efficacy of transcranial direct current stimulation as an adjuvant to naming and spelling therapy in the treatment of oral and written naming in individuals with primary progressive aphasia. Frontiers in Human Neuroscience Sep 2025.

177 Chen, B.B., Haeusermann, T., Dada, A., Hamilton, R.H., James, J.E., Fong, K.C., Dohan, D., Chiong, W.: Race-ethnicity, rurality, and age in prospective preferences and concerns regarding closed-loop implanted neural devices. Journal of Neuropsychiatry and Clinical Neurosciences 37(1): 79-87, Aug 2025.

149 Parchure, S., Xu, Z., Shah-Basak, P., Erickson, B., Harvey, D., Wurzman, R., McAfee, D., Sacchetti, D., Faseyitan, O., Hamilton, R.H.: Predicting neuroplasticity effects of continuous theta burst stimulation with biomarkers from the motor evoked potential TMS input-output curve 3b Clinical Neurophysiology Jul 2025.

181 Hinkle, S.N., Okeh, C.C., Ulloa-Pérez, E., Mani, A., Higginbotham, E.J., Thomas, R., Kearney, M.D., Fahl, C., Schisterman, E.F., Verma, S.S., Hamilton, R., Mumford, S.L.: Perceptions of institutional engagement and inclusion by sexual orientation and gender identity. JAMA Network Open 8(6): e2513772, Jun 2025.

12a Stoll, H., Kelkar, A., Turkeltaub, P.E., Hamilton, R.H., Coslett, B., Medaglia, J.D.: Lesion-induced changes to the network controllability of the right pars triangularis in aphasia. Neurobiology of Language 1(17), Jun 2025.

167 D'Alonzo, B.A., Schneider, A.L.C., Erz, A., Master, C.L., Barnett, I.J., Hamilton, R.H., Wiebe, D.J., Szymczak, J.E.: A qualitative study of collegiate student-athlete experiences of recovery after concussion. Journal of Head Trauma Rehabilitation Page: Online ahead of print. May 2025.

15e D'Alonzo, B.A., Schneider, A.Lc., Barnett, I.J., Master, C.L., Hamilton, R.H., Weibe, D.J.: Concurrent symptom domains and associations with recovery timelines among collegiate athletes with sport-related concussion. British Journal of Sports Medicine 59(7): 461-469, Mar 2025.

187 Dresang, H.C., Harvey, D.Y., Vnenchak, L., Parchure, S., Cason, S., Twigg, P., Faseyitan, O., Maher, L.M., Hamilton, R.H., Coslett, H.B.: Semantic and phonological abilities inform efficacy of transcranial magnetic stimulation on sustained aphasia treatment outcomes. Neurobiology of Language 6: nol_a_00160, Mar 2025.

112 Fernandez, K.A., Erickson, B.A., Kable, J.W., Hamilton, R.H., Medaglia, J.D.: Evaluating risk and benefit sensitivity for cognitive treatments. Journal of Cognitive Enhancement 9(2): 214-229, Mar 2025.

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26 Last updated: 02/12/2026
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